Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 171981..172468 Replicon chromosome
Accession NZ_CP051196
Organism Treponema sp. OMZ 906

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag E4N69_RS00735 Protein ID WP_162662026.1
Coordinates 171981..172247 (-) Length 89 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag E4N69_RS00740 Protein ID WP_162662027.1
Coordinates 172247..172468 (-) Length 74 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
E4N69_RS00705 (E4N69_00705) 166995..167318 - 324 WP_253824162.1 hypothetical protein -
E4N69_RS00710 (E4N69_00710) 167315..169411 - 2097 WP_253824163.1 heavy metal translocating P-type ATPase -
E4N69_RS00715 (E4N69_00715) 169433..169651 - 219 WP_162662024.1 hypothetical protein -
E4N69_RS00730 (E4N69_00730) 170162..171919 + 1758 WP_253824164.1 phosphoenolpyruvate--protein phosphotransferase -
E4N69_RS00735 (E4N69_00735) 171981..172247 - 267 WP_162662026.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
E4N69_RS00740 (E4N69_00740) 172247..172468 - 222 WP_162662027.1 DUF6290 family protein Antitoxin
E4N69_RS00745 (E4N69_00745) 172660..174141 + 1482 WP_253824165.1 ribosome biogenesis GTPase Der -
E4N69_RS00750 (E4N69_00750) 174117..174482 + 366 WP_230977822.1 MerR family transcriptional regulator -
E4N69_RS00755 (E4N69_00755) 174553..175209 + 657 WP_253824166.1 hypothetical protein -
E4N69_RS00760 (E4N69_00760) 175230..176018 + 789 WP_162662030.1 RNA polymerase sigma factor WhiG -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-86)

Antitoxin

Protein of unknown function DUF6290

(1-71)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10389.87 Da        Isoelectric Point: 9.9931

>T153762 WP_162662026.1 NZ_CP051196:c172247-171981 [Treponema sp. OMZ 906]
MYRVETTARFDKEFKKLDKYTQRMIAAWIDKNLEGSENPRVHGKGLTANRSGQWRYRIGDYRLICAIQDNELVILALTVG
HRRTVYDQ

Download         Length: 267 bp

>T153762 NZ_CP067087:c2220056-2219730 [Croceicoccus sp. YJ47]
TTGAAAAAAGCGGCTGCGAGCAAGCGTGCCGCGCTTCCCCGGACGATTGGCTATGCGAAGTCCTTCCTGAAGGACTTCGA
GCGGCTGTCGCGTTCCGGCCGATACGATATGAAAAAGCTCAAGCAGGTTATGCTGCTGCTCATCGCCAATGACGCGCCGC
TCGGCCCCGAATGGAAAGACCACACTCTCAAGGGGGAATGGCAGGGTCACCGCGAATGCCATGTTGGTGGCGATTTCCTG
CTGATCTATCGCGTGGATGACATTCCGGCACCCGGCGGCGGCATTTTCTTCACCCGCGCCGGAACACACAGTGAGCTTTT
CAAATGA

Antitoxin


Download         Length: 74 a.a.        Molecular weight: 8205.29 Da        Isoelectric Point: 5.1069

>AT153762 WP_162662027.1 NZ_CP051196:c172468-172247 [Treponema sp. OMZ 906]
MAFSIRLTEAERAIANSYAKLHSVSLGEAFKNALFEKIEDEYDITVAAEAYQEYVSTGKKSRPFSELKKELGL

Download         Length: 222 bp

>AT153762 NZ_CP067087:c2220346-2220053 [Croceicoccus sp. YJ47]
ATGATTCATGTCCGGATGGACAATGATCTGAAAGACCGCGCGACTGAGGCGCTGGCGGCGATGGGTCTGTCGACCGCCGA
TGCCGTGCGCCTGCTGTTCCATCGCATCGCCACCGACCAGGCCTTTCCGCTGGAGCTCAAGGTTCCCAACGCGGAAACCC
GCGCGGCGATGGAAGAGGCGGATGAGTTCTTTAAGAACGGTGGCGCGCCCCGCTTCGATAATGCTGACGAAATGTTCGCC
GAGCTCGAGGAAGAGAGCAAAGCCCTGCGCGAGGCCGGAAAAGCAAAGTCTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References