Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | hicAB/HicA-HicB |
| Location | 2586955..2587530 | Replicon | chromosome |
| Accession | NZ_CP051195 | ||
| Organism | Treponema sp. OMZ 803 strain BF2M | ||
Toxin (Protein)
| Gene name | hicA | Uniprot ID | - |
| Locus tag | ABH09_RS11810 | Protein ID | WP_162664517.1 |
| Coordinates | 2586955..2587143 (+) | Length | 63 a.a. |
Antitoxin (Protein)
| Gene name | hicB | Uniprot ID | - |
| Locus tag | ABH09_RS11815 | Protein ID | WP_162664518.1 |
| Coordinates | 2587147..2587530 (+) | Length | 128 a.a. |
Genomic Context
Location: 2583649..2585358 (1710 bp)
Type: Others
Protein ID: WP_253714559.1
Type: Others
Protein ID: WP_253714559.1
Location: 2586326..2586556 (231 bp)
Type: Others
Protein ID: WP_253714560.1
Type: Others
Protein ID: WP_253714560.1
Location: 2586955..2587143 (189 bp)
Type: Toxin
Protein ID: WP_162664517.1
Type: Toxin
Protein ID: WP_162664517.1
Location: 2587147..2587530 (384 bp)
Type: Antitoxin
Protein ID: WP_162664518.1
Type: Antitoxin
Protein ID: WP_162664518.1
Location: 2588050..2590035 (1986 bp)
Type: Others
Protein ID: WP_253714563.1
Type: Others
Protein ID: WP_253714563.1
Location: 2590083..2590580 (498 bp)
Type: Others
Protein ID: WP_162664523.1
Type: Others
Protein ID: WP_162664523.1
Location: 2590591..2591418 (828 bp)
Type: Others
Protein ID: WP_253714564.1
Type: Others
Protein ID: WP_253714564.1
Location: 2591507..2592439 (933 bp)
Type: Others
Protein ID: WP_253714565.1
Type: Others
Protein ID: WP_253714565.1
Location: 2585435..2585659 (225 bp)
Type: Others
Protein ID: WP_162664516.1
Type: Others
Protein ID: WP_162664516.1
Location: 2586651..2586827 (177 bp)
Type: Others
Protein ID: WP_253714561.1
Type: Others
Protein ID: WP_253714561.1
Location: 2587549..2587923 (375 bp)
Type: Others
Protein ID: WP_253714562.1
Type: Others
Protein ID: WP_253714562.1
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| ABH09_RS11790 (ABH09_11795) | 2583649..2585358 | + | 1710 | WP_253714559.1 | methyl-accepting chemotaxis protein | - |
| ABH09_RS11795 (ABH09_11800) | 2585435..2585659 | - | 225 | WP_162664516.1 | YdbC family protein | - |
| ABH09_RS11800 (ABH09_11805) | 2586326..2586556 | + | 231 | WP_253714560.1 | hypothetical protein | - |
| ABH09_RS11805 (ABH09_11810) | 2586651..2586827 | - | 177 | WP_253714561.1 | hypothetical protein | - |
| ABH09_RS11810 (ABH09_11815) | 2586955..2587143 | + | 189 | WP_162664517.1 | type II toxin-antitoxin system HicA family toxin | Toxin |
| ABH09_RS11815 (ABH09_11820) | 2587147..2587530 | + | 384 | WP_162664518.1 | type II toxin-antitoxin system HicB family antitoxin | Antitoxin |
| ABH09_RS11820 (ABH09_11825) | 2587549..2587923 | - | 375 | WP_253714562.1 | hypothetical protein | - |
| ABH09_RS11825 (ABH09_11830) | 2588050..2590035 | + | 1986 | WP_253714563.1 | exodeoxyribonuclease V subunit gamma | - |
| ABH09_RS11830 (ABH09_11835) | 2590083..2590580 | + | 498 | WP_162664523.1 | hypothetical protein | - |
| ABH09_RS11835 (ABH09_11840) | 2590591..2591418 | + | 828 | WP_253714564.1 | purine-nucleoside phosphorylase | - |
| ABH09_RS11840 (ABH09_11845) | 2591507..2592439 | + | 933 | WP_253714565.1 | RluA family pseudouridine synthase | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| No matching records found | |||||||
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 63 a.a. Molecular weight: 7192.35 Da Isoelectric Point: 10.1294
>T153761 WP_162664517.1 NZ_CP051195:2586955-2587143 [Treponema sp. OMZ 803]
MTFKEIEKLIKKDGWYLQSTIGSHYHYVHDSKKGKVTIPFHGNKELSKYVVNSILKQAGLKE
MTFKEIEKLIKKDGWYLQSTIGSHYHYVHDSKKGKVTIPFHGNKELSKYVVNSILKQAGLKE
Download Length: 189 bp
>T153761 NZ_CP067074:469756-470049 [Rhizobium sp. AB2/73]
GTGAAACTTACTTGGTCTGCGTTCGCGTTATCGGATCGCGACGCCATCTTCACATACATTGAGGCAGATAATCCTGCGGC
CGCCGTTCTGGTCGACGAACGGATAGTCGCAGCCTCACGTCGCTTGCTCGATTTTCCCGCCAGCGGCCGTGTTGGTAGAA
TTGCCGGTACACGCGAACTCGTCATCAACGGCACGCCCTACGTAGCTGTTTATGCCGTTACCGACACGACAGTTCGAATT
CTTCGTGTATTGCATGGCGCGCAGGAATGGCCAGAGTCTGTGCCGATAAGCTAA
GTGAAACTTACTTGGTCTGCGTTCGCGTTATCGGATCGCGACGCCATCTTCACATACATTGAGGCAGATAATCCTGCGGC
CGCCGTTCTGGTCGACGAACGGATAGTCGCAGCCTCACGTCGCTTGCTCGATTTTCCCGCCAGCGGCCGTGTTGGTAGAA
TTGCCGGTACACGCGAACTCGTCATCAACGGCACGCCCTACGTAGCTGTTTATGCCGTTACCGACACGACAGTTCGAATT
CTTCGTGTATTGCATGGCGCGCAGGAATGGCCAGAGTCTGTGCCGATAAGCTAA
Antitoxin
Download Length: 128 a.a. Molecular weight: 14207.24 Da Isoelectric Point: 4.4076
>AT153761 WP_162664518.1 NZ_CP051195:2587147-2587530 [Treponema sp. OMZ 803]
MYIYPAFFYKDNDGYSVVFKDLELATGGSTLQEALLMAEEALTGRVYLMLQDGETLPAATEIGNITKPQDADFVTLIKTD
KKYLIQDKSVRKNVTLPAWLAEAAENANLNFSQELQNALKQRLQIAL
MYIYPAFFYKDNDGYSVVFKDLELATGGSTLQEALLMAEEALTGRVYLMLQDGETLPAATEIGNITKPQDADFVTLIKTD
KKYLIQDKSVRKNVTLPAWLAEAAENANLNFSQELQNALKQRLQIAL
Download Length: 384 bp
>AT153761 NZ_CP067074:469451-469759 [Rhizobium sp. AB2/73]
ATGGCCGCAAACGCACTTGTCCAAACACGTATTGATGCCGAGGTTCGGGATCGTGCCTCTGCCGTTCTTGAGAGCATGGG
CCTTACGGTATCCGATGCGGTCCGTATATTGCTTACACGGACTGCCAACGAAGGGGCGCTCCCCCTTGAGCTCCTTTCGG
GGAGTGAGGCTCATGACGTTTGGTTTCGCAACAAGGTGCTCGAAGCGCTAAACGATACTCGCCCGGACGTATCCGACGAC
GAGGTTGAGGCGCATTTTGCCGAACGTCGAGCGGCTGCCCGTCTTAAAGCTGGTGCGCTCAAATCGTGA
ATGGCCGCAAACGCACTTGTCCAAACACGTATTGATGCCGAGGTTCGGGATCGTGCCTCTGCCGTTCTTGAGAGCATGGG
CCTTACGGTATCCGATGCGGTCCGTATATTGCTTACACGGACTGCCAACGAAGGGGCGCTCCCCCTTGAGCTCCTTTCGG
GGAGTGAGGCTCATGACGTTTGGTTTCGCAACAAGGTGCTCGAAGCGCTAAACGATACTCGCCCGGACGTATCCGACGAC
GAGGTTGAGGCGCATTTTGCCGAACGTCGAGCGGCTGCCCGTCTTAAAGCTGGTGCGCTCAAATCGTGA