Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | vapBC/VapC-VagC |
Location | 2273559..2274190 | Replicon | chromosome |
Accession | NZ_CP051195 | ||
Organism | Treponema sp. OMZ 803 strain BF2M |
Toxin (Protein)
Gene name | vapC | Uniprot ID | - |
Locus tag | ABH09_RS10320 | Protein ID | WP_253714321.1 |
Coordinates | 2273559..2273960 (-) | Length | 134 a.a. |
Antitoxin (Protein)
Gene name | vapB | Uniprot ID | - |
Locus tag | ABH09_RS10325 | Protein ID | WP_253714322.1 |
Coordinates | 2273960..2274190 (-) | Length | 77 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
ABH09_RS10305 (ABH09_10305) | 2269391..2271157 | - | 1767 | WP_253714318.1 | ABC transporter ATP-binding protein | - |
ABH09_RS10310 (ABH09_10310) | 2271154..2272932 | - | 1779 | WP_253714319.1 | ABC transporter ATP-binding protein | - |
ABH09_RS10315 (ABH09_10315) | 2273040..2273486 | - | 447 | WP_253714320.1 | hypothetical protein | - |
ABH09_RS10320 (ABH09_10320) | 2273559..2273960 | - | 402 | WP_253714321.1 | type II toxin-antitoxin system VapC family toxin | Toxin |
ABH09_RS10325 (ABH09_10325) | 2273960..2274190 | - | 231 | WP_253714322.1 | type II toxin-antitoxin system VapB family antitoxin | Antitoxin |
ABH09_RS10330 (ABH09_10330) | 2274333..2274947 | - | 615 | WP_162664234.1 | TetR/AcrR family transcriptional regulator | - |
ABH09_RS10335 (ABH09_10335) | 2275123..2276490 | - | 1368 | WP_162664235.1 | HD domain-containing protein | - |
ABH09_RS10340 (ABH09_10340) | 2276518..2277753 | - | 1236 | WP_253672900.1 | cation:dicarboxylase symporter family transporter | - |
ABH09_RS10345 (ABH09_10345) | 2278011..2278595 | - | 585 | WP_162664237.1 | flavin reductase family protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 134 a.a. Molecular weight: 15357.65 Da Isoelectric Point: 4.7187
>T153760 WP_253714321.1 NZ_CP051195:c2273960-2273559 [Treponema sp. OMZ 803]
MYLLDTNICIFLIKNTFPVLTKRIFSTSGNDLFLSSISIAEMEYGASKSQNREKNRKALLDFCVDFNILDFTAEDTETYG
MIRAYLEKEGSVIGPYDMQIAAQAMTRNLIVITNNYDEFARIPWIKVEDWTKK
MYLLDTNICIFLIKNTFPVLTKRIFSTSGNDLFLSSISIAEMEYGASKSQNREKNRKALLDFCVDFNILDFTAEDTETYG
MIRAYLEKEGSVIGPYDMQIAAQAMTRNLIVITNNYDEFARIPWIKVEDWTKK
Download Length: 402 bp
>T153760 NZ_CP067074:c356466-355984 [Rhizobium sp. AB2/73]
ATGCTTTCCGCTCCGGCGCTTCTTGAGGAGGCGCATGACCTTGACCTGTTCCAGAGCGGAAACGATACGCTCGATGAATG
GCTGCGCCGCCGCGCGCGACCCAATCAGGTCAGCGGTGCGTCCCGGACCTATGTCGTCGCCGAGGGGCAGCGCGTCGTCG
GCTATTATTGCCTTGCGTCTGGCGCGCTCGATCTGGCCGATGCGCCGGGATCGGTTCGGCGAAACATGCCAGATCCAATT
CCCATGGCGGTTCTTGGTCGGCTTGCCATCGATCGCGGTTGGCAGGGCAGGGGATTGGGCGCGGCGCTTTTGCAGGATGC
CGTCCTTCGCACATCGCAGGCGGCGTCCATCATGGGCATTCGCGGCCTTCTTGTGCATGCGATTTCCGAAGACGCCAAAG
CCTTTTACGAGCACTATGGTTTCCTATGCTCTCCCAATCAACCCATGACGCTGGTGCTCTCGCTTAAGATCAGGACCGGA
TAG
ATGCTTTCCGCTCCGGCGCTTCTTGAGGAGGCGCATGACCTTGACCTGTTCCAGAGCGGAAACGATACGCTCGATGAATG
GCTGCGCCGCCGCGCGCGACCCAATCAGGTCAGCGGTGCGTCCCGGACCTATGTCGTCGCCGAGGGGCAGCGCGTCGTCG
GCTATTATTGCCTTGCGTCTGGCGCGCTCGATCTGGCCGATGCGCCGGGATCGGTTCGGCGAAACATGCCAGATCCAATT
CCCATGGCGGTTCTTGGTCGGCTTGCCATCGATCGCGGTTGGCAGGGCAGGGGATTGGGCGCGGCGCTTTTGCAGGATGC
CGTCCTTCGCACATCGCAGGCGGCGTCCATCATGGGCATTCGCGGCCTTCTTGTGCATGCGATTTCCGAAGACGCCAAAG
CCTTTTACGAGCACTATGGTTTCCTATGCTCTCCCAATCAACCCATGACGCTGGTGCTCTCGCTTAAGATCAGGACCGGA
TAG
Antitoxin
Download Length: 77 a.a. Molecular weight: 8840.16 Da Isoelectric Point: 6.9785
>AT153760 WP_253714322.1 NZ_CP051195:c2274190-2273960 [Treponema sp. OMZ 803]
MVCAKVFMSGNSQAVRIPKEFHIDDTELFIKKIGTTIILYPQNRPWENLKKSLSEFSDDFMAEGRKQPSLTERETF
MVCAKVFMSGNSQAVRIPKEFHIDDTELFIKKIGTTIILYPQNRPWENLKKSLSEFSDDFMAEGRKQPSLTERETF
Download Length: 231 bp
>AT153760 NZ_CP067074:c356750-356466 [Rhizobium sp. AB2/73]
ATGGCCACAAAATCGTTGACGGACTCACATGCCAAGCCGGTCCACCTGCGTATCCGCGAGGACGTGCGCAAGGTGATCGA
TCGCGCCGCCAGCATTCGCGGCAAGAGCCGCACGGATTTCATGATCGATGCGGCTTACCGCGCTGCGGAAGACGCCTTGC
TCGACCAAACTCTTGTGCGGGTTGATGAGGACAGCTATCGCCACTTCCTCTCCGTCCTCGATCAGCCGCCGAATGGGGAA
GGTTTCGAGCGGTTGATGAACGCGCCCAAGCCTTGGCAGTCCTGA
ATGGCCACAAAATCGTTGACGGACTCACATGCCAAGCCGGTCCACCTGCGTATCCGCGAGGACGTGCGCAAGGTGATCGA
TCGCGCCGCCAGCATTCGCGGCAAGAGCCGCACGGATTTCATGATCGATGCGGCTTACCGCGCTGCGGAAGACGCCTTGC
TCGACCAAACTCTTGTGCGGGTTGATGAGGACAGCTATCGCCACTTCCTCTCCGTCCTCGATCAGCCGCCGAATGGGGAA
GGTTTCGAGCGGTTGATGAACGCGCCCAAGCCTTGGCAGTCCTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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