Detailed information of TA system TA153757

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): yoeB-relB/YoeB-RelB
• Location: 797109..797619
• Replicon: chromosome
• Accession: NZ_CP051195
• Organism: Treponema sp. OMZ 803 strain BF2M

Toxin (Protein)

• Gene name: yoeB
• Uniprot ID: -
• Locus tag: ABH09_RS03675
• Protein ID: WP_253715242.1
• Coordinates: 797109..797369 (-)
• Length: 87 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: ABH09_RS03680
• Protein ID: WP_253715243.1
• Coordinates: 797362..797619 (-)
• Length: 86 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
ABH09_RS03655 (ABH09_03655)	794919..795263	+	345	WP_253715238.1	hypothetical protein	-
ABH09_RS03660 (ABH09_03660)	795463..795678	+	216	WP_253715239.1	hypothetical protein	-
ABH09_RS03665 (ABH09_03665)	795887..796687	-	801	WP_253715240.1	class I SAM-dependent methyltransferase	-
ABH09_RS03670 (ABH09_03670)	796697..797038	-	342	WP_162662790.1	PadR family transcriptional regulator	-
ABH09_RS03675 (ABH09_03675)	797109..797369	-	261	WP_253715242.1	Txe/YoeB family addiction module toxin	Toxin
ABH09_RS03680 (ABH09_03680)	797362..797619	-	258	WP_253715243.1	type II toxin-antitoxin system prevent-host-death family antitoxin	Antitoxin
ABH09_RS03685 (ABH09_03685)	797814..799586	-	1773	WP_253715245.1	ABC transporter ATP-binding protein	-
ABH09_RS03690 (ABH09_03690)	799583..800407	-	825	WP_253715246.1	ABC transporter permease	-
ABH09_RS03695 (ABH09_03695)	800404..801357	-	954	WP_253715247.1	ABC transporter permease	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin YoeB (5-84)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-70)

Sequences

Toxin

Protein

• Length: 87 a.a.
• Molecular weight: 10611.17 Da
• Isoelectric Point: 9.7986

>T153757 WP_253715242.1 NZ_CP051195:c797369-797109 [Treponema sp. OMZ 803]
MNKLFTDEAWNDYIYWFNTDKKILEKINDLIKEIERTPFTGKGKPEPLKHALSGYWSRRINQEHRIVYQVDEKQLVFISF
RYHYKK

Nucleotide

• Length: 261 bp

>T153757 NZ_CP067072:545971-546375 [Rhizobium sp. AB2/73]
TTGAGTAAGCTCTACATGCTGGATACCAACATCGTATCCGAGCTTGCCCGAAACCCACAGGGTATCGTTGCCAGGCGTAT
CGCCGATGTCGGGCCAGATGCAATTTGCGTCAGCATTATTACGGCCGCAGAATTGCGCTATGGCTGCGCTAAAAAGGGAT
CGCCGAAATTGCTGGCACAGATCGAGGCTATCCTGGGAAGCATACCGGTACTCGCGCTCGATGTTCCTGCCGATGCCGAA
TACGGAGCCATCAGGGCCGAGCTGGAAGTTGCCGGCAAACCCATCGGCCCAAACGACCTGTTGATTGCTGCCCATGCTCA
TGCGCTGGAGGCGGTCCTGGTAACAGCTAATATCGGCGAGTTTAAGCGCGTCCGCGATCTCCGTGTCGAAAACTGGCTGG
ATTGA

Antitoxin

Protein

• Length: 86 a.a.
• Molecular weight: 10163.36 Da
• Isoelectric Point: 5.4836

>AT153757 WP_253715243.1 NZ_CP051195:c797619-797362 [Treponema sp. OMZ 803]
MDVITYSDLRRNLKTYMDKVYYDYEPLMIARKNSENLVLLSVHEYNSLVETDYLLHNEANAEHLKKSIEQHRNGNLHSHE
LLENE

Nucleotide

• Length: 258 bp

>AT153757 NZ_CP067072:545705-545974 [Rhizobium sp. AB2/73]
ATGCGCCATCTCCGACATAACGAACCTAGCCCACCACGAGAAGCCAAGCTGTTTCGCAACAACAAGAGCCAGGCCGTACG
CATCCCGGCTGACTTCGAACTTCCTGGCGATCGGGTGATGATCCACCGGGAAGGAGACCGGCTTATTATCGAGCCGGTGC
GCCGCAAGAGCTTGCTTGACGTTTTGGCAAGTTTGGAGCCTCTCGGACCAGAGGATCAATTTCCCGATATAGATGATACT
CTGCTGCCAGCGAAAGAAATCGAGCTTTGA