Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 174807..175294 Replicon chromosome
Accession NZ_CP051195
Organism Treponema sp. OMZ 803 strain BF2M

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag ABH09_RS00735 Protein ID WP_162662026.1
Coordinates 174807..175073 (-) Length 89 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag ABH09_RS00740 Protein ID WP_162662027.1
Coordinates 175073..175294 (-) Length 74 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ABH09_RS00705 (ABH09_00715) 169822..170145 - 324 WP_253714821.1 hypothetical protein -
ABH09_RS00710 (ABH09_00720) 170142..172238 - 2097 WP_253714822.1 heavy metal translocating P-type ATPase -
ABH09_RS00715 (ABH09_00725) 172260..172478 - 219 WP_162662024.1 hypothetical protein -
ABH09_RS00730 (ABH09_00740) 172988..174745 + 1758 WP_253714823.1 phosphoenolpyruvate--protein phosphotransferase -
ABH09_RS00735 (ABH09_00745) 174807..175073 - 267 WP_162662026.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
ABH09_RS00740 (ABH09_00750) 175073..175294 - 222 WP_162662027.1 DUF6290 family protein Antitoxin
ABH09_RS00745 (ABH09_00755) 175486..176967 + 1482 WP_253714824.1 ribosome biogenesis GTPase Der -
ABH09_RS00750 (ABH09_00760) 176943..177308 + 366 WP_253714825.1 MerR family transcriptional regulator -
ABH09_RS00755 (ABH09_00765) 177379..178035 + 657 WP_162662029.1 hypothetical protein -
ABH09_RS00760 (ABH09_00770) 178056..178844 + 789 WP_253714826.1 RNA polymerase sigma factor WhiG -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-86)

Antitoxin

Protein of unknown function DUF6290

(1-71)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10389.87 Da        Isoelectric Point: 9.9931

>T153755 WP_162662026.1 NZ_CP051195:c175073-174807 [Treponema sp. OMZ 803]
MYRVETTARFDKEFKKLDKYTQRMIAAWIDKNLEGSENPRVHGKGLTANRSGQWRYRIGDYRLICAIQDNELVILALTVG
HRRTVYDQ

Download         Length: 267 bp

>T153755 NZ_CP067071:c3694341-3694045 [Rhizobium sp. AB2/73]
GTGAAACTTGCTTGGACTCCCGAAGCAAGGGCTGACCGACGCGCAATCTATACCTACATCGAGGCCGAGAATGCCACCGC
CGCACTCGCGCTGGACGAACTCTTGGCCAAACGGTCGAAACAGCTCATTACTCATCCAATGACGGGCCGACCCGGCCGCG
TGTCCGGGACACGCGAGCTCGTCGTGCACAGAAACTATCTGCTGGTTTATGATCTTGCTGATGAAATGGTGCGCATAATC
CGCATTCTGCATGCCGCACAGCAATGGCCGCCGAGCGATTTTCAGCCGATTCCCTAG

Antitoxin


Download         Length: 74 a.a.        Molecular weight: 8205.29 Da        Isoelectric Point: 5.1069

>AT153755 WP_162662027.1 NZ_CP051195:c175294-175073 [Treponema sp. OMZ 803]
MAFSIRLTEAERAIANSYAKLHSVSLGEAFKNALFEKIEDEYDITVAAEAYQEYVSTGKKSRPFSELKKELGL

Download         Length: 222 bp

>AT153755 NZ_CP067071:c3694628-3694338 [Rhizobium sp. AB2/73]
ATGACCGACGCGACATTTACCTTCCGAGTTGAAGAAGAGTTGAAGGCGGCTTTCAGCGAGGCTGCGAAAGCGCATGATCA
AACCGGTGCGCAATTGCTCCGGGCTTTCATGCGCGATTATGTGCGGCGCCAGCAAGATGCCGCCGAATATGACATTTGGT
TTCGCCAGCAGGTTCAGGCCGGTCTTACTTCCGCCAATGCCGGCAACCTCATTCCCGACGACGACGTGGACGCTGAATTT
GCCGCCTTGCGAGAAGAAACACGCCGCAAACTCAGCGGGCGTTCTTCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References