Detailed information of TA system TA153735

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): EcnAB/-
• Location: 4758399..4758784
• Replicon: chromosome
• Accession: NZ_CP051190
• Organism: Xanthomonas sp. SS

Toxin (Protein)

• Gene name: EcnB
• Uniprot ID: A0A0K2ZHE5
• Locus tag: HEP74_RS20150
• Protein ID: WP_003469322.1
• Coordinates: 4758399..4758533 (-)
• Length: 45 a.a.

Antitoxin (Protein)

• Gene name: EcnA
• Uniprot ID: -
• Locus tag: HEP74_RS20155
• Protein ID: WP_185814371.1
• Coordinates: 4758632..4758784 (-)
• Length: 51 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
HEP74_RS20130	4754467..4755390	-	924	WP_185814368.1	MBL fold metallo-hydrolase	-
HEP74_RS20135	4755668..4756960	-	1293	WP_185814369.1	tryptophan--tRNA ligase	-
HEP74_RS20140	4757071..4757910	+	840	WP_185814370.1	hypothetical protein	-
HEP74_RS20145	4757983..4758198	-	216	WP_145703764.1	CsbD family protein	-
HEP74_RS20150	4758399..4758533	-	135	WP_003469322.1	entericidin A/B family lipoprotein	Toxin
HEP74_RS20155	4758632..4758784	-	153	WP_185814371.1	entericidin A/B family lipoprotein	Antitoxin
HEP74_RS20160	4758928..4759851	-	924	WP_185814372.1	arginase	-
HEP74_RS20170	4760265..4761113	-	849	WP_185814373.1	SPOR domain-containing protein	-
HEP74_RS20175	4761123..4761863	-	741	WP_185814374.1	type III pantothenate kinase	-
HEP74_RS20180	4761860..4762855	-	996	WP_185814375.1	bifunctional biotin--[acetyl-CoA-carboxylase] ligase/biotin operon repressor BirA	-
HEP74_RS20185	4762993..4763265	+	273	WP_185814376.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Entericidin A/B (23-42)

Antitoxin

• Entericidin A/B (23-39)

Sequences

Toxin

Protein

• Length: 45 a.a.
• Molecular weight: 4604.40 Da
• Isoelectric Point: 9.2977

>T153735 WP_003469322.1 NZ_CP051190:c4758533-4758399 [Xanthomonas sp. SS]
MKRTFAWMLLAMFSVGLLSGCNTVAGAGKDVKSAGEKVEDAAKN

Nucleotide

• Length: 135 bp

>T153735 NZ_CP067066:c1061014-1060673 [Raoultella sp. XY-1]
ATGTGGGACATAGAAACGACGGACGCTTTCGATGAGTGGTTTGCGGCACAGACGGGTACGCTGCAGGAAGACATGCTGGC
CGCTATGGTGATTTTATCTGAGTATGGCCCACAGTTAGGCAGGCCGTTTGCAGATACCGTGAATGATTCTGCTTTTCCGA
ACATGAAAGAATTGCGCGTACAGCATCAAGGCAACCCAATCCGAGCCTTCTTTGCGTTTGATCCTTCCCGCCATGGCATC
GTGCTATACGCCGGAGACAAAACGGGGTTGAACGAAAAGAAATTTTACAGAGACATGCTCAGGCTTGCCGATAATGAATA
CCGTAAGCAACTGAATAAATGA

Antitoxin

Protein

• Length: 51 a.a.
• Molecular weight: 5305.33 Da
• Isoelectric Point: 7.5953

>AT153735 WP_185814371.1 NZ_CP051190:c4758784-4758632 [Xanthomonas sp. SS]
MKRLLTLMMLTLFCAGMLTGCNTMAGAGKDMQKAGDKVETKADDCSDGKC

Nucleotide

• Length: 153 bp

>AT153735 NZ_CP067066:c1060663-1060364 [Raoultella sp. XY-1]
ATGGCTACCCTTAAAGAACTGATGGCTAAGCAAAGTCCAGAAAGCCGGGAGCGTATTGCCGAAAAAGTGGAAGAACTTCG
CCAGACGATCGCTTTAAACATGCTTAGGGAAGAGCTGAATATTTCTCAAACGGAGCTGGCGGCGGCGATGGGCGTTAAGC
AGCCAACGGTCGCAAAAATGGAGCAGGCAGATAACGATCCCCGCCTGTCGACCCTGAAACGTTACGTCACCGCTCTGGGC
GGCGAACTCAGTATTGACGTGAAGCTCCCAACGGGCAAAAGGGTCGCATTTCACCTCTGA

Structures

Toxin

• AlphaFold DB: A0A0K2ZHE5