Detailed information of TA system TA153734

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/YoeB-YefM
• Location: 3742368..3742873
• Replicon: chromosome
• Accession: NZ_CP051190
• Organism: Xanthomonas sp. SS

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: HEP74_RS15485
• Protein ID: WP_185813645.1
• Coordinates: 3742616..3742873 (+)
• Length: 86 a.a.

Antitoxin (Protein)

• Gene name: relE
• Uniprot ID: A0A1C3TRJ9
• Locus tag: HEP74_RS15480
• Protein ID: WP_003468816.1
• Coordinates: 3742368..3742619 (+)
• Length: 84 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
HEP74_RS15450	3738218..3738514	-	297	WP_185813640.1	hypothetical protein	-
HEP74_RS15455	3738707..3739162	+	456	WP_185813641.1	hypothetical protein	-
HEP74_RS15460	3739300..3739905	-	606	WP_185816663.1	hypothetical protein	-
HEP74_RS15465	3740158..3740607	-	450	WP_185813642.1	nuclear transport factor 2 family protein	-
HEP74_RS15470	3740731..3741453	+	723	WP_185813643.1	ArsR family transcriptional regulator	-
HEP74_RS15475	3741450..3742214	-	765	WP_185813644.1	endonuclease	-
HEP74_RS15480	3742368..3742619	+	252	WP_003468816.1	type II toxin-antitoxin system prevent-host-death family antitoxin	Antitoxin
HEP74_RS15485	3742616..3742873	+	258	WP_185813645.1	Txe/YoeB family addiction module toxin	Toxin
HEP74_RS15495	3743158..3743511	-	354	WP_003468813.1	PilZ domain-containing protein	-
HEP74_RS15500	3743508..3744485	-	978	WP_185813646.1	DNA polymerase III subunit delta'	-
HEP74_RS15505	3744482..3745150	-	669	WP_185813647.1	dTMP kinase	-
HEP74_RS15510	3745147..3746205	-	1059	WP_185813648.1	endolytic transglycosylase MltG	-
HEP74_RS15515	3746281..3747630	-	1350	WP_185813649.1	aminodeoxychorismate synthase component I	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin YoeB (5-84)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-74)

Sequences

Toxin

Protein

• Length: 86 a.a.
• Molecular weight: 10187.71 Da
• Isoelectric Point: 9.6587

>T153734 WP_185813645.1 NZ_CP051190:3742616-3742873 [Xanthomonas sp. SS]
VTLQFSDNAWEDYLYWQQTDKKMLKRVNDLIKAIQRDPFQGVGKPEPLRHALAGYWSRRINDEHRIVYKVEAGILLIAQL
RYHYV

Nucleotide

• Length: 258 bp

>T153734 NZ_CP067066:856001-856411 [Raoultella sp. XY-1]
GTGGTCCTGTGGCAATCTGATTTACGCATCTCCTGGCGCTCACAGTGGTTCTCGCTGCTGCTGCACGGCATTGTGGCGGC
TATTGTGCTGCTGATGCCCTGGCCGCTGAGCTACACGCCGCTATGGCTATTGCTGCTGTCGCTGGTGGTGTTCGACAGCG
TGCGCAGCCAGCGGCGGATCCACGCCTGCCGGGGGGAAATAAAGCTGATGACCGATTCGCGTTTGCGTTGGCAAAAAGCG
GAATGGGAGATTGTCGGCACGCCGTGGGTGATTAATAGCGGGATGTTGCTGCGTCTGCAGGATATGCAAACGCGTCGCCG
CCAGCATCTGTGGATCGCTGCAGACAGTATGGACGCCAAAGAGTGGCGAGATCTGCGCCGGTTGGTGTTACAAAAACCGG
CACAGGAGTAA

Antitoxin

Protein

• Length: 84 a.a.
• Molecular weight: 9281.56 Da
• Isoelectric Point: 5.1186

>AT153734 WP_003468816.1 NZ_CP051190:3742368-3742619 [Xanthomonas sp. SS]
MDTITYSAARAALADTMERVVNNHEPVIITRSREQSVVMLSLEDYKAMEETAYLLRSPKSAQRLLESIAQLEAGRGKARD
LAE

Nucleotide

• Length: 252 bp

>AT153734 NZ_CP067066:855754-856020 [Raoultella sp. XY-1]
ATGGACATTACGAATAAAGCCCGCATCCACTGGGCATGCCGCAGGGGTATGCGTGAACTTGATATCTCCATCATGCCGTT
TTTCGAGTATGAGTACGATACGCTCAGCGATGAAGACAAACAGCTGTTTATCCGTCTGTTAGAAAACGACGATCCGGATC
TGTTTAACTGGCTGATGAATCATGGCGAACCGGCTGATGCGCAACTGCAACGGATGGTAAAATTAATCCAGACTCGGAAT
CGGGAACGTGGTCCTGTGGCAATCTGA

Structures

Antitoxin

• AlphaFold DB: A0A1C3TRJ9