Detailed information of TA system TA153733

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): vapBC/VapC-VagC
• Location: 3703271..3703917
• Replicon: chromosome
• Accession: NZ_CP051190
• Organism: Xanthomonas sp. SS

Toxin (Protein)

• Gene name: vapC
• Uniprot ID: -
• Locus tag: HEP74_RS15330
• Protein ID: WP_185813618.1
• Coordinates: 3703271..3703684 (-)
• Length: 138 a.a.

Antitoxin (Protein)

• Gene name: vapB
• Uniprot ID: -
• Locus tag: HEP74_RS15335
• Protein ID: WP_185813619.1
• Coordinates: 3703681..3703917 (-)
• Length: 79 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
HEP74_RS15310	3698371..3699018	-	648	WP_185813614.1	HAD family phosphatase	-
HEP74_RS15315	3699041..3700222	-	1182	WP_185813615.1	MFS transporter	-
HEP74_RS15320	3700557..3701882	-	1326	WP_185813616.1	ATP-binding protein	-
HEP74_RS15325	3701869..3703260	-	1392	WP_185813617.1	sigma-54 dependent transcriptional regulator	-
HEP74_RS15330	3703271..3703684	-	414	WP_185813618.1	type II toxin-antitoxin system VapC family toxin	Toxin
HEP74_RS15335	3703681..3703917	-	237	WP_185813619.1	AbrB/MazE/SpoVT family DNA-binding domain-containing protein	Antitoxin
HEP74_RS15340	3704014..3706452	-	2439	WP_185813620.1	ABC transporter permease	-
HEP74_RS15345	3706449..3707219	-	771	WP_185813621.1	ABC transporter ATP-binding protein	-
HEP74_RS15350	3707238..3708488	-	1251	WP_185813622.1	efflux RND transporter periplasmic adaptor subunit	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (6-125)

Antitoxin

• SpoVT-AbrB domain (8-42)

Sequences

Toxin

Protein

• Length: 138 a.a.
• Molecular weight: 15061.41 Da
• Isoelectric Point: 7.9954

>T153733 WP_185813618.1 NZ_CP051190:c3703684-3703271 [Xanthomonas sp. SS]
MSQPLYLLDTNICIYIINRRPPGVLDRFAALRIGQVAISSITGAELAYGVDKSGSPRNRQALDKFLAPLDILPFDEAAMR
RYGALRSGLERKGTPIGALDQLIAAHALALDAVLVTNNVREFERVVGLRLENWVSTE

Nucleotide

• Length: 414 bp

>T153733 NZ_CP067066:c67475-67167 [Raoultella sp. XY-1]
ATACAGTATTACGTTTATAAAAATACCGGTCGAATTACTGTGTATCCTTATCTCCTTGATGTACAAAGTGACATTATTGG
AATGCGCAATACCCGGGTCGTGATCCCACTATTCCCGCTGAGAAATTACAAAGGTCCGCGCGCCGATCGTTTAACACCGG
TTGTCACCGTAGAAGGGGAAGAATACGTCGTGATGACTCACGAACTCGCCAGCATCCCACAACGCGTTCTGGGGGAAGAG
GTTTGTCATCTCAATCACCAACGTGAAGTCGTTAAAGCATCAATAGATTTTCTTTTTGACGGGATTTAA

Antitoxin

Protein

• Length: 79 a.a.
• Molecular weight: 8991.29 Da
• Isoelectric Point: 5.0976

>AT153733 WP_185813619.1 NZ_CP051190:c3703917-3703681 [Xanthomonas sp. SS]
MTTTAKLFQSGRSQAVRLPKALRFEGEEVIARRFGNGVLLLPLDAPWQLLREALEEFEPGFQLQREQPEQQVRGEWPV

Nucleotide

• Length: 237 bp

>AT153733 NZ_CP067066:c67714-67478 [Raoultella sp. XY-1]
ATGCCAGCCGTAAAACACAATAAGCAGAATGTCAGCGTGACGCTGGATCCTATACTGGTCAAACAGGCTCGTGAGATCGG
CATCAATCTTTCTCAAACGTTGACGAGCGCTCTAAAAAGCGAAATCCACAGCATCGAAATGGCACGCTGGCAAAAAGAAA
ATGCCAGGGCAATCGACTACCTCAATGATTTAACAGAGGAAAATGGACTTCTCTCTGACGAATACAGGACGTTTTAA