Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ataRT/DUF1778(antitoxin)
Location 792225..792977 Replicon chromosome
Accession NZ_CP051190
Organism Xanthomonas sp. SS

Toxin (Protein)


Gene name ataT Uniprot ID -
Locus tag HEP74_RS03435 Protein ID WP_185815196.1
Coordinates 792501..792977 (+) Length 159 a.a.

Antitoxin (Protein)


Gene name ataR Uniprot ID -
Locus tag HEP74_RS03430 Protein ID WP_184412216.1
Coordinates 792225..792497 (+) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HEP74_RS03410 787939..789207 + 1269 WP_185815193.1 MFS transporter -
HEP74_RS03415 789235..790221 - 987 WP_185815194.1 siroheme synthase -
HEP74_RS03420 790314..790886 + 573 WP_185816480.1 ANTAR domain-containing protein -
HEP74_RS03425 790894..792009 + 1116 WP_185815195.1 ABC transporter substrate-binding protein -
HEP74_RS03430 792225..792497 + 273 WP_184412216.1 DUF1778 domain-containing protein Antitoxin
HEP74_RS03435 792501..792977 + 477 WP_185815196.1 GNAT family N-acetyltransferase Toxin
HEP74_RS03440 793092..793625 + 534 WP_185815197.1 hypothetical protein -
HEP74_RS03445 793887..794594 + 708 WP_185815198.1 hypothetical protein -
HEP74_RS03450 794591..795346 + 756 WP_185815199.1 hypothetical protein -
HEP74_RS03455 796456..797625 + 1170 WP_185816481.1 NarK/NasA family nitrate transporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(43-144)

Antitoxin

Vibrio phage ICP1, Orf50

(5-89)


Sequences

Toxin        


Download         Length: 159 a.a.        Molecular weight: 17228.00 Da        Isoelectric Point: 8.3739

>T153732 WP_185815196.1 NZ_CP051190:792501-792977 [Xanthomonas sp. SS]
MSLTAPGPLTDGHRLDDFQCSAPELTRWLLERAHQNQLSGASRCFVVCDGQRRVVGYYALAAGVVAHEDAPGRIRRNMPN
PVPVIVLGRLAVHVDWAGQGIGKGLLKDAVQRTLQVCEQVGARALLCHAIDEAAKAFYLKHGFIASPIHDMTVMLPLR

Download         Length: 477 bp

>T153732 NZ_CP067061:c57641-57330 [Klebsiella pneumoniae]
ATGCACGTAATTTCAAAAGAGCCTTTTGAGGAAGCGGCAAAGCGATATCCCAACGATTCGTTAGCCATTCGGGCGTTGTA
CCGCTTAGTGCGCGAGACGGACTTCTCTTCTCCAGCTGAGATGCTAACTCTGATACCGAGCCTGGATAATTTTAAGTACA
GGAATAAGTGGTGGGTTTTGGATGTAGGGGGCAACAACTTAAGGGTTATCGCCTATATCAATTTCGTAAATAAGCGCTTC
TACGTGAAGCACATCGCAACCCACGCTGATTACGACAAGTTGACCCGCTATTACAGGGAGAACAAAGAATGA

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 9988.44 Da        Isoelectric Point: 8.0583

>AT153732 WP_184412216.1 NZ_CP051190:792225-792497 [Xanthomonas sp. SS]
MSTAASKVINFRAPAAKQALIDHAVEVSGMNRTEFILDAVCEKAREVLADQTRFALSRQQLQRFNALLDAPLESNAAIRR
LLSTPAPWEH

Download         Length: 273 bp

>AT153732 NZ_CP067061:c57333-56914 [Klebsiella pneumoniae]
ATGATTACCGACACTGCAAAAGCCATTGAAGCAACCAAACAACTCGTAGCTGCCGTCCCCTTCCTAGGGGGCAGTTCTTC
CGAGAGCGATTACCGCGAAGCGATGGAGCTGGTGGATTATCTGATCGAGAACGACGACGAGAACCCACTTATTGACTTCC
TGGCGAGTAAGATTGCCGACTATGAAGATAACAGCCCTCGTTTCGCTGAGTTCAACAAAGCTATTGCTGAAATACCAGTC
GGCGTTGCACTTCTGCGAACCCTGATTGACCAGCACAAGCTGTCTTATTCAGACCTTAAGGATGAGATCGGATCTAAATC
ATTGGTCAGCCAAATCCTGTCAGGGCAGCGCTCTTTGACCATCACTCACATAAAAGCTCTTTCCGCGCGCTTCGGTGTAA
AACCTGAGTGGTTCCTATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References