Detailed information of TA system TA153732

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): ataRT/DUF1778(antitoxin)
• Location: 792225..792977
• Replicon: chromosome
• Accession: NZ_CP051190
• Organism: Xanthomonas sp. SS

Toxin (Protein)

• Gene name: ataT
• Uniprot ID: -
• Locus tag: HEP74_RS03435
• Protein ID: WP_185815196.1
• Coordinates: 792501..792977 (+)
• Length: 159 a.a.

Antitoxin (Protein)

• Gene name: ataR
• Uniprot ID: -
• Locus tag: HEP74_RS03430
• Protein ID: WP_184412216.1
• Coordinates: 792225..792497 (+)
• Length: 91 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
HEP74_RS03410	787939..789207	+	1269	WP_185815193.1	MFS transporter	-
HEP74_RS03415	789235..790221	-	987	WP_185815194.1	siroheme synthase	-
HEP74_RS03420	790314..790886	+	573	WP_185816480.1	ANTAR domain-containing protein	-
HEP74_RS03425	790894..792009	+	1116	WP_185815195.1	ABC transporter substrate-binding protein	-
HEP74_RS03430	792225..792497	+	273	WP_184412216.1	DUF1778 domain-containing protein	Antitoxin
HEP74_RS03435	792501..792977	+	477	WP_185815196.1	GNAT family N-acetyltransferase	Toxin
HEP74_RS03440	793092..793625	+	534	WP_185815197.1	hypothetical protein	-
HEP74_RS03445	793887..794594	+	708	WP_185815198.1	hypothetical protein	-
HEP74_RS03450	794591..795346	+	756	WP_185815199.1	hypothetical protein	-
HEP74_RS03455	796456..797625	+	1170	WP_185816481.1	NarK/NasA family nitrate transporter	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• GNAT domain (43-144)

Antitoxin

• Vibrio phage ICP1, Orf50 (5-89)

Sequences

Toxin

Protein

• Length: 159 a.a.
• Molecular weight: 17228.00 Da
• Isoelectric Point: 8.3739

>T153732 WP_185815196.1 NZ_CP051190:792501-792977 [Xanthomonas sp. SS]
MSLTAPGPLTDGHRLDDFQCSAPELTRWLLERAHQNQLSGASRCFVVCDGQRRVVGYYALAAGVVAHEDAPGRIRRNMPN
PVPVIVLGRLAVHVDWAGQGIGKGLLKDAVQRTLQVCEQVGARALLCHAIDEAAKAFYLKHGFIASPIHDMTVMLPLR

Nucleotide

• Length: 477 bp

>T153732 NZ_CP067061:c57641-57330 [Klebsiella pneumoniae]
ATGCACGTAATTTCAAAAGAGCCTTTTGAGGAAGCGGCAAAGCGATATCCCAACGATTCGTTAGCCATTCGGGCGTTGTA
CCGCTTAGTGCGCGAGACGGACTTCTCTTCTCCAGCTGAGATGCTAACTCTGATACCGAGCCTGGATAATTTTAAGTACA
GGAATAAGTGGTGGGTTTTGGATGTAGGGGGCAACAACTTAAGGGTTATCGCCTATATCAATTTCGTAAATAAGCGCTTC
TACGTGAAGCACATCGCAACCCACGCTGATTACGACAAGTTGACCCGCTATTACAGGGAGAACAAAGAATGA

Antitoxin

Protein

• Length: 91 a.a.
• Molecular weight: 9988.44 Da
• Isoelectric Point: 8.0583

>AT153732 WP_184412216.1 NZ_CP051190:792225-792497 [Xanthomonas sp. SS]
MSTAASKVINFRAPAAKQALIDHAVEVSGMNRTEFILDAVCEKAREVLADQTRFALSRQQLQRFNALLDAPLESNAAIRR
LLSTPAPWEH

Nucleotide

• Length: 273 bp

>AT153732 NZ_CP067061:c57333-56914 [Klebsiella pneumoniae]
ATGATTACCGACACTGCAAAAGCCATTGAAGCAACCAAACAACTCGTAGCTGCCGTCCCCTTCCTAGGGGGCAGTTCTTC
CGAGAGCGATTACCGCGAAGCGATGGAGCTGGTGGATTATCTGATCGAGAACGACGACGAGAACCCACTTATTGACTTCC
TGGCGAGTAAGATTGCCGACTATGAAGATAACAGCCCTCGTTTCGCTGAGTTCAACAAAGCTATTGCTGAAATACCAGTC
GGCGTTGCACTTCTGCGAACCCTGATTGACCAGCACAAGCTGTCTTATTCAGACCTTAAGGATGAGATCGGATCTAAATC
ATTGGTCAGCCAAATCCTGTCAGGGCAGCGCTCTTTGACCATCACTCACATAAAAGCTCTTTCCGCGCGCTTCGGTGTAA
AACCTGAGTGGTTCCTATAA