Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ataRT/DUF1778(antitoxin)
Location 822269..823021 Replicon chromosome
Accession NZ_CP051189
Organism Xanthomonas sp. GW

Toxin (Protein)


Gene name ataT Uniprot ID -
Locus tag HEP73_RS03560 Protein ID WP_185815196.1
Coordinates 822545..823021 (+) Length 159 a.a.

Antitoxin (Protein)


Gene name ataR Uniprot ID -
Locus tag HEP73_RS03555 Protein ID WP_184412216.1
Coordinates 822269..822541 (+) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HEP73_RS03535 817977..819245 + 1269 WP_185822144.1 MFS transporter -
HEP73_RS03540 819279..820265 - 987 WP_185822145.1 siroheme synthase -
HEP73_RS03545 820358..820930 + 573 WP_100225477.1 ANTAR domain-containing protein -
HEP73_RS03550 820938..822053 + 1116 WP_185822146.1 ABC transporter substrate-binding protein -
HEP73_RS03555 822269..822541 + 273 WP_184412216.1 DUF1778 domain-containing protein Antitoxin
HEP73_RS03560 822545..823021 + 477 WP_185815196.1 GNAT family N-acetyltransferase Toxin
HEP73_RS03565 823135..823350 + 216 WP_185822147.1 hypothetical protein -
HEP73_RS03570 823402..823677 + 276 WP_185822148.1 hypothetical protein -
HEP73_RS03575 823750..824535 + 786 WP_185822149.1 hypothetical protein -
HEP73_RS03580 825636..826805 + 1170 WP_185823278.1 NarK/NasA family nitrate transporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(43-144)

Antitoxin

Vibrio phage ICP1, Orf50

(5-89)


Sequences

Toxin        


Download         Length: 159 a.a.        Molecular weight: 17228.00 Da        Isoelectric Point: 8.3739

>T153727 WP_185815196.1 NZ_CP051189:822545-823021 [Xanthomonas sp. GW]
MSLTAPGPLTDGHRLDDFQCSAPELTRWLLERAHQNQLSGASRCFVVCDGQRRVVGYYALAAGVVAHEDAPGRIRRNMPN
PVPVIVLGRLAVHVDWAGQGIGKGLLKDAVQRTLQVCEQVGARALLCHAIDEAAKAFYLKHGFIASPIHDMTVMLPLR

Download         Length: 477 bp

>T153727 NZ_CP067060:c2743052-2741730 [Klebsiella pneumoniae]
ATGGCGACGCTTACCACCTGGATGAACAATGTGCGCGTGGGAACCTTAACCCGCCAGGCTAACGGGGCGCACAGTTTTCG
CTATGAGGAAGAGTGGCTGCGCAGCCCGCGCGCCAGACCGCTCTCTCTCTCACTGCCGCTGCAGTATGGCAATATCACGG
CCGACGCGGTGTATCACTATTTTGATAACCTGCTGCCCGACAGCCCGCAGGTCCGCGACCGGATCGTCAGGCGCTATCAA
GCGCGCTCGAAGCAGCCGTTCGATCTGCTGGCCGAAGTCGGGCGGGATAGCGTAGGGGCGGTTACCCTCCTGCCGCCGGG
GGAAGAGGCGCACCTGGAAGGATTACGCTGGCAGACGCTGGACGAGGCGCAGCTCACCGCTTTGCTGACCGCTTACCAGT
CGGATATCCCCCTCGGGATGATTACCGGCCAGGACGATTTCCGTATCTCGGTGGCCGGCGCCCAGGAGAAAACGGCGCTG
CTGCGGATGGGCGAGCAGTGGTGTATTCCGCAGGGCGCCACGCCGACCACGCATATCATTAAGCTGCCCATCGGCGAGAT
CAAGCAGCCCAATGCGACGCTGGATCTGCGTGAAAGCGTGGATAATGAGTTTCTGTGCCTGGCGCTGGCCAGAGAACTGG
GCCTGGCGGTGCCGGAAGCGGAGATCATCACCACCCCGCGGATCCGCGCCCTGGCGGTAACCCGCTTCGACCGGCGCTGG
GCGCAGGAGGGACGGGTGCTGCTGCGTCTGCCGCAGGAGGATCTGTGTCAGGCTTTTGGTCTTCCTTCAGCGATGAAATA
TGAGTCTGACGGCGGGCCGGGTATCGCCGCGATCATGACCTTTCTGCTGGGCTCGAGTGAAGCGCTGAAAGATCGCTATG
ACTTTATGAAGTTCATGGTCTTCCAGTGGCTGACGGGGGCGACGGACGGTCACGCAAAAAACTTCTCAATTTACCTGTTG
CCCGGCGGCAGCTACCGCTTAACACCGTTCTACGACATTATTTCGGCGTTTCCGGTGCTGGGCGGCACGGGACTGCATCT
GCGCGATCTGAAGCTGTCGATGGGGCTCAATGCCACAAAAGGGCGTAAAACAGAGATTAACGCCATCTATCCGCGTCATT
TTCTGGCGACGGCCAAAGCGGTGAACTTTCCCCGGGAGCAGATGCTGGCGATCCTCCAGGAGTTTGCCGGGCATGTGCCG
CAGGCAATCGAAAGCGCTCGCCGGACGCTGCCGGCGGACTTTTCCAGCCACGTCTGGCAGGCCATTACAGAGAACATGCT
GAAGCTGCACGCCCGCCTGCAGCAAGGGCTGCAGGCGCTATAG

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 9988.44 Da        Isoelectric Point: 8.0583

>AT153727 WP_184412216.1 NZ_CP051189:822269-822541 [Xanthomonas sp. GW]
MSTAASKVINFRAPAAKQALIDHAVEVSGMNRTEFILDAVCEKAREVLADQTRFALSRQQLQRFNALLDAPLESNAAIRR
LLSTPAPWEH

Download         Length: 273 bp

>AT153727 NZ_CP067060:c2743318-2743052 [Klebsiella pneumoniae]
ATGAATTCCCCGCAGATATACAGTCCCGTGCAGCTGGCCAATTACCTGAAGCTGCTGCGCCAGCAGAACCACTGGACCCA
GGATGCGCTGGCCAGGCGGATCGGCATTAAGCAGGCCACGCTGTCCAATTTTGAAAATCACCCCGACAAAACCACCTTAA
CCACGCTGTTTAAGATCCTCCAGTCGCTGGGGGTGGTGATGACGCTGAACGCCAAAGCTGCTGAGACGGCGCCGGCTCCC
GATAACAACACGGACCTTGACTGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References