Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacT-ataR/DUF1778(antitoxin)
Location 1701527..1702287 Replicon chromosome
Accession NZ_CP051180
Organism Ferrimonas lipolytica strain S7

Toxin (Protein)


Gene name tacT Uniprot ID -
Locus tag HER31_RS07985 Protein ID WP_168660083.1
Coordinates 1701527..1702030 (-) Length 168 a.a.

Antitoxin (Protein)


Gene name ataR Uniprot ID -
Locus tag HER31_RS07990 Protein ID WP_168660084.1
Coordinates 1702021..1702287 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HER31_RS07965 1696527..1697300 + 774 WP_168660079.1 flagellar biosynthetic protein FliR -
HER31_RS07970 1697310..1698446 + 1137 WP_168660080.1 flagellar type III secretion system protein FlhB -
HER31_RS07975 1698452..1700530 + 2079 WP_168660081.1 flagellar biosynthesis protein FlhA -
HER31_RS07980 1700620..1701402 + 783 WP_168660082.1 hypothetical protein -
HER31_RS07985 1701527..1702030 - 504 WP_168660083.1 GNAT family N-acetyltransferase Toxin
HER31_RS07990 1702021..1702287 - 267 WP_168660084.1 DUF1778 domain-containing protein Antitoxin
HER31_RS07995 1702419..1703093 - 675 WP_168660085.1 cold shock domain-containing protein -
HER31_RS08000 1703384..1703803 - 420 WP_168660086.1 transcriptional regulator -
HER31_RS08005 1704005..1706881 - 2877 WP_168660087.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(44-146)

Antitoxin

Vibrio phage ICP1, Orf50

(2-88)


Sequences

Toxin        


Download         Length: 168 a.a.        Molecular weight: 18037.76 Da        Isoelectric Point: 9.4788

>T153724 WP_168660083.1 NZ_CP051180:c1702030-1701527 [Ferrimonas lipolytica]
MGINKPRIITDNDSTASFSCGVASLDVWLRQQALRSNARGTAKTYVVTDSQTEEVVGYYAIAMGSVSRSSAFSSLKRNSP
DPIPMVVLARSAVDARYQGQGVAIGLLKDCMLRSVAAMEVVGGAGILVHAVDDQARNFYTKFGFRESPIDRLVLMIRSCD
LVASLKK

Download         Length: 504 bp

>T153724 NZ_CP067060:732139-732624 [Klebsiella pneumoniae]
ATGATCTCGGCACCAGAACCGCTTCATGCCGGGCATATTCTTACCCCGTTTTGCTGCGGTATAGATTCCATGGATCACTG
GCTGAAACAGCGGGCGATGAAAAATCAGGTTACTGGCGCATCCCGCACCTTTGTCTGCTGCGACGACGCGAAGGTGATGG
CTTACTACTCACTGGCTTCCAGCGCTGTGACGACAAATACTGCGCCGGGTCGTTTTCGCCGCAATATGCCTGACCCGATC
CCGGTTGTGGTACTGGGTCGTCTGGCGGTGGATAAATCACTACATGGGAAAGGTGTCGGGCGGGCGCTGGTACGTGATGC
CGGGCTGCGTGTGATTCAGGTGGCGGAGACTATCGGCATTCGCGGGATGCTGGTTCACGCCCTGTCGGATGAAGCACGGG
ATTTTTACCTGCGGGTGGGGTTTGAGCCGTCGCCGATGGATTCGATGATGTTGATGGTGACGTTGAGGGATTTGGTTAAT
GCCTGA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 9890.24 Da        Isoelectric Point: 4.6017

>AT153724 WP_168660084.1 NZ_CP051180:c1702287-1702021 [Ferrimonas lipolytica]
MATKSAAINMRVLPSVREVIDAAASLQSMDRTVFIQQAALNEAYKVLADQKDFKLEQRAFEAFETALDEPAKVSEGVQDL
FQRKSPWE

Download         Length: 267 bp

>AT153724 NZ_CP067060:731849-732142 [Klebsiella pneumoniae]
ATGCCAGCCGCAAACAGCATGTCCATAAAACGCGAAACGTTAAATCTGCGCATTAAACCTGCCGAACGCGATCTTATTGA
TCGGGCGGCGAAAGCCAGAGGGAAAAACCGCACAGACTTTGTGCTGGAGGCCGCCCGCGCTGCCGCTGAGGAAGCGCTGA
TTGAGCAACGCATCATTATGGCCGATCCGCAGGCTTATCAGGAATTTCTCGCTCGTCTGGATCAGGCTCCTGCACCTAAT
GCCGCACTGCGTAAAACTATGCAGACCCCTGCGCCGTGGGAACAGGAAGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References