Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 2261662..2262199 Replicon chromosome
Accession NZ_CP051175
Organism Ralstonia solanacearum strain Rs5

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag HF906_RS10480 Protein ID WP_043891999.1
Coordinates 2261662..2261922 (+) Length 87 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag HF906_RS10485 Protein ID WP_003268459.1
Coordinates 2261915..2262199 (+) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HF906_RS10460 2257795..2258712 - 918 WP_003268451.1 sugar ABC transporter substrate-binding protein -
HF906_RS10465 2258931..2259983 - 1053 WP_141515298.1 LacI family DNA-binding transcriptional regulator -
HF906_RS10470 2260118..2261275 + 1158 WP_003268454.1 fatty acid desaturase family protein -
HF906_RS10475 2261241..2261552 + 312 WP_003268456.1 Rieske 2Fe-2S domain-containing protein -
HF906_RS10480 2261662..2261922 + 261 WP_043891999.1 addiction module antitoxin RelB Toxin
HF906_RS10485 2261915..2262199 + 285 WP_003268459.1 putative addiction module antidote protein Antitoxin
HF906_RS10490 2262219..2263064 - 846 WP_003268460.1 TIM barrel protein -
HF906_RS10495 2263061..2264098 - 1038 WP_193010113.1 xylose isomerase -
HF906_RS10500 2264095..2265384 - 1290 WP_003268463.1 FAD-dependent oxidoreductase -
HF906_RS10505 2265552..2266469 + 918 WP_013206304.1 MurR/RpiR family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(1-81)

Antitoxin

Uncharacterized protein HI1420

(6-91)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 9378.78 Da        Isoelectric Point: 10.5111

>T153720 WP_043891999.1 NZ_CP051175:2261662-2261922 [Ralstonia solanacearum]
MRDKRAKARIVARLVSASFGNFGDCKPVGEGVSEMRIDVGAGYRVYYTRQGTVVYILLTGGSKATQAQDIKQAIRMARGL
KESGHD

Download         Length: 261 bp

>T153720 NZ_CP067058:c65303-64824 [Rahnella aceris]
ATGAGTTTACAATTGTCTGCTCCTGAGCCACTTACAACTGCACATATCCTTGACGCTTTCGGTTGTGGGGAAACAACGTT
AGATGAATGGTTAAAACGGCGCGCTCTGACAAACCACTTAAACGGTGCAAGTCGTACTTTTGTTGTCACGGCTCACGATA
AAAGTGTTGTTGGTTATTATGCACTCGCAGCCGGTGCTGTGTCGCACAGGGAAGCGGCAGGATCTGTTCGGCGTAATATG
CCTGATCCTATTCCGGTCATAGTATTGGGAAGACTGGCGGTCGACCTTCGCACTCAAGGAGTAAAGTTAGGTTCATCATT
GCTACAGGATGCCGTTCTTCGAGTTCGCTCAATTGTTGAAAACACAGGGGTCAGAGCATTGCTCGTACATGCACTTCATG
AACCGGCTAAACAATTTTATGAACACTACGGTTTTACATCATCGCCAATTAATCCGATGACATTAATGCTACGCCTTTAG

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 9919.31 Da        Isoelectric Point: 5.0492

>AT153720 WP_003268459.1 NZ_CP051175:2261915-2262199 [Ralstonia solanacearum]
MTEAYAPFDTAAYLDSEETIAEFLAAAMDDPNPDVFLAALGAVARARGIAKVAADAGLGRESLYKAISPGAHPRYETVRK
IVRALGVRLNVTPA

Download         Length: 285 bp

>AT153720 NZ_CP067058:c65560-65300 [Rahnella aceris]
ATGCGTGACGCTGCGATTAATTTGCGTGCTTTGCCGGAACAACGTGATCTCATAGATCAAGCCGCCAGCCTATTAGGTAA
AAACCGATCTGATTTTATGTTGGAAGTAGCGTGTGAGCGCGCACAAGCTATTCTGCTCGACCAAGTTTTTTTCCAGTTAG
ATACTGAGAAATTTCATGAATTCACAGCGATGCTTGACGCACCTCACAATGCAAATCAAGGTCTGGAACGTCTGATGGCA
GTTAAAGCGCCTTGGGCATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References