Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/COG3657-dnstrm_HI1420
Location 999523..1000133 Replicon plasmid pUW773mp
Accession NZ_CP051172
Organism Ralstonia solanacearum strain RUN2279

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag HF908_RS22275 Protein ID WP_193029203.1
Coordinates 999523..999831 (+) Length 103 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag HF908_RS22280 Protein ID WP_016722339.1
Coordinates 999828..1000133 (+) Length 102 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HF908_RS22255 995851..996444 - 594 WP_193029195.1 GNAT family N-acetyltransferase -
HF908_RS22260 996577..997128 + 552 WP_193029197.1 helix-turn-helix transcriptional regulator -
HF908_RS22265 997306..998121 + 816 WP_193029199.1 GntR family transcriptional regulator -
HF908_RS22270 998248..999447 + 1200 WP_193029201.1 MFS transporter -
HF908_RS22275 999523..999831 + 309 WP_193029203.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
HF908_RS22280 999828..1000133 + 306 WP_016722339.1 putative addiction module antidote protein Antitoxin
HF908_RS22285 1000346..1001659 + 1314 WP_193029205.1 metabolite/H+ symporter -
HF908_RS22290 1001855..1002016 - 162 WP_193029856.1 hypothetical protein -
HF908_RS22300 1003075..1003932 - 858 Protein_817 IS5 family transposase -
HF908_RS22305 1004065..1004733 - 669 WP_193029797.1 hypothetical protein -
HF908_RS22310 1004899..1005067 - 169 Protein_819 IS5/IS1182 family transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - acrB / fliI / fliM / flgG / flgC / cyaB / motA / cheW / cheB / cheY / adeG 1..1911272 1911272


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(3-94)

Antitoxin

Cro/C1-type helix-turn-helix domain

(52-96)


Sequences

Toxin        


Download         Length: 103 a.a.        Molecular weight: 11783.57 Da        Isoelectric Point: 7.1355

>T153714 WP_193029203.1 NZ_CP051172:999523-999831 [Ralstonia solanacearum]
MLTIRTTEIFDDWFCSLRDKAAQRRIQVRIDRLQMGNPGDMKAVRDGIRELRIDHGPGYRLYVVQHGVVLIVLLCGGDKS
TQEADIRRAIDLSRRLDVDDME

Download         Length: 309 bp

>T153714 NZ_CP067057:2370387-2370590 [Rahnella aceris]
ATGAACAAAATCGACTATTTGATGCGTTTACGAAAATGCACCACTATCGATACACTTGAACGTGTTATTGAAAAAAATAA
GTACGAACTTTCCGACGACGAGCTGGAATTGTTTTACTCGGCAGCTGACCATCGTTTAGCGGAGCTAACGATGAACAAGT
TGTACGATAAAATCCCGGTATCAGTCTGGAAATTTGTACGCTGA

Antitoxin


Download         Length: 102 a.a.        Molecular weight: 10967.57 Da        Isoelectric Point: 7.2780

>AT153714 WP_016722339.1 NZ_CP051172:999828-1000133 [Ralstonia solanacearum]
MTMAQRTIKTRPWDSAEHLRTEADIAAYLDACLEEAGDDPAFITHALGVVARSRGMTQLARETGMTREGLYKALSEGGNP
SFATVLKVIRALGIRLHAVPT

Download         Length: 306 bp

>AT153714 NZ_CP067057:2369973-2370341 [Rahnella aceris]
ATGGATGAGTACTCGCCTAAGCGGCACGATATCGCTCAGTTACGCTACCTGAATGAAATGCTGTATGATGAAGGGATTGC
GACACTGGGTGACAGTCATCATGGTTGGGTTAACGATCCGACTTCGGCTGTTAACTTGCAGCTCAATGAACTGATTGAGC
ACATTGCATCCTTTGTGATGAGTTTTAAAATTAAGTATCCAGACGATAACCATTTAAGTGATCTGGTTGAAGAGTATCTG
GATGATACCTACACGCTGTTCAGTAATTATGGAATTAACGATTCTGATTTACGCCAATGGCAAAAGACCAAGAAGCGGTT
ATTCAGAATGTTCTCAGGGGACTACATCTGTACCCTAATGAAGACTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References