Detailed information of TA system TA153710

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/RHH(antitoxin)
• Location: 1191770..1192314
• Replicon: chromosome
• Accession: NZ_CP051171
• Organism: Ralstonia solanacearum strain RUN2279

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: HF908_RS05690
• Protein ID: WP_193027890.1
• Coordinates: 1191770..1192045 (-)
• Length: 92 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: HF908_RS05695
• Protein ID: WP_193027891.1
• Coordinates: 1192045..1192314 (-)
• Length: 90 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
HF908_RS05660	1187173..1187589	+	417	WP_193027885.1	hypothetical protein	-
HF908_RS05665	1187660..1189009	+	1350	WP_193027886.1	replication-associated recombination protein A	-
HF908_RS05670	1189076..1190392	+	1317	WP_193027887.1	serine--tRNA ligase	-
HF908_RS05680	1190616..1191179	+	564	WP_193027888.1	recombinase family protein	-
HF908_RS05685	1191157..1191717	-	561	WP_193027889.1	DUF2726 domain-containing protein	-
HF908_RS05690	1191770..1192045	-	276	WP_193027890.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
HF908_RS05695	1192045..1192314	-	270	WP_193027891.1	ribbon-helix-helix domain-containing protein	Antitoxin
HF908_RS05700	1192361..1192663	-	303	WP_193028451.1	hypothetical protein	-
HF908_RS05705	1192849..1193067	-	219	Protein_1119	NAD(P)H-dependent oxidoreductase	-
HF908_RS05710	1193258..1194037	-	780	WP_193027892.1	alpha/beta hydrolase	-
HF908_RS05715	1194169..1194492	+	324	Protein_1121	LysR family transcriptional regulator	-
HF908_RS05720	1194572..1195588	+	1017	WP_193027114.1	IS21 family transposase	-
HF908_RS05725	1195585..1196373	+	789	WP_193027111.1	IS21-like element ISRso19 family helper ATPase IstB	-
HF908_RS05730	1196449..1197030	+	582	Protein_1124	LysR family transcriptional regulator	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	1181423..1215148	33725

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (3-90)

Antitoxin

• Ribbon-helix-helix protein, CopG (9-46)

Sequences

Toxin

Protein

• Length: 92 a.a.
• Molecular weight: 10630.33 Da
• Isoelectric Point: 10.1779

>T153710 WP_193027890.1 NZ_CP051171:c1192045-1191770 [Ralstonia solanacearum]
MEVKWTGKAVSDITRLYEFLSQVNKPAAIRVVQSLTGAPKSLVVNPRIGEQLDEFEPREVRRIIVGQYEMRYAIRGSVIY
VLRLWHTREDR

Nucleotide

• Length: 276 bp

>T153710 NZ_CP067057:c52009-51608 [Rahnella aceris]
ATGAAAACTTCAACGTCGGCGGCACCGTCAGCGGTGCCCGTATCATCATCTCCGTCGCCCGTGGCCGTTTGGCGGCAACT
GCTGACGTACCTGTTCGACCGCCATTACGGCCTGACGCTCAACGACACGCCATTCCACTATGAATCCGTGATAGAGGAAT
ATATTGATGCCGGTATTTCTTTGAAAGATGCGGTGAACTTTGTGGCTGAACGATATGGCCTGCTGCGCATTGACTGCAGC
AGCTTTTCTTTAACGGAGCAGCCGCAGTTCATTTCCTACGTCAACATTCTTCAGGCGCGTCGGGCCACCGGCCTGATGCA
ACAAGAAGGGTATAAAGAGATAAGCGTTCTCACTCAGGGCAAAAGGACCACCGAAGGCAGGACAAATGAAAACTCCCGTT
AA

Antitoxin

Protein

• Length: 90 a.a.
• Molecular weight: 10056.37 Da
• Isoelectric Point: 6.7268

>AT153710 WP_193027891.1 NZ_CP051171:c1192314-1192045 [Ralstonia solanacearum]
MAHLDTRVLTAHVPVQLAERVDQIAERLERSRGWIMKQALSAWIDQEEERSRLTREALADVDAGTVIDHQAVQAWADSLS
TSKPKKAPR

Nucleotide

• Length: 270 bp

>AT153710 NZ_CP067057:c52453-52085 [Rahnella aceris]
ATGACGTTGCCACTCCTCCCGGCCACTCAGCCAACTGTCGCCCCTGCCCGCCCGCAATGGGGGCTGAGGCACGATATCCC
CCCGTGCTTCGGTGCCCGCCTGGTCCAAGAAAGCAGCCGCCTGTATTTTCTGGTTGACCGGGCAGGCTTCTGTGGTGCAT
TCAGCGCCGACGACGCCCTGCGGATCGACCAGGCATTTCCACTGATACTCAAACAGCTGGAGCGGATGCTGGTGACCGGT
GAGCTCAATCCTCGCCATCAGCAACGCGTTACGCTGCATCACAATGGCTTGACCTGCGACGCCGACCCCCTCGGGTCGCA
TGGCTATGTGTACCTGTCCATTTATCCGACCCCACCTGCGGAAACATGA