Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YoeB-RelB
Location 1184491..1184945 Replicon chromosome
Accession NZ_CP051168
Organism [Phormidium] sp. ETS-05

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag HEQ85_RS05290 Protein ID WP_199248613.1
Coordinates 1184742..1184945 (+) Length 68 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag HEQ85_RS05285 Protein ID WP_199248612.1
Coordinates 1184491..1184745 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HEQ85_RS05245 1179750..1180994 + 1245 WP_199248606.1 transposase -
HEQ85_RS05250 1181290..1181577 + 288 WP_054466246.1 type II toxin-antitoxin system RelE/ParE family toxin -
HEQ85_RS05255 1181699..1182010 + 312 WP_199248607.1 HigA family addiction module antidote protein -
HEQ85_RS05260 1182169..1182342 + 174 WP_199248608.1 hypothetical protein -
HEQ85_RS05265 1182363..1182605 - 243 WP_199248609.1 type II toxin-antitoxin system VapB family antitoxin -
HEQ85_RS05270 1182710..1183237 + 528 Protein_1033 DUF29 domain-containing protein -
HEQ85_RS05275 1183745..1184044 - 300 WP_199248610.1 hypothetical protein -
HEQ85_RS05280 1184229..1184366 - 138 WP_199248611.1 hypothetical protein -
HEQ85_RS05285 1184491..1184745 + 255 WP_199248612.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
HEQ85_RS05290 1184742..1184945 + 204 WP_199248613.1 Txe/YoeB family addiction module toxin Toxin
HEQ85_RS05295 1185553..1186005 - 453 WP_199248614.1 DUF29 domain-containing protein -
HEQ85_RS05300 1186275..1187312 + 1038 WP_199248615.1 glycosyltransferase family 4 protein -
HEQ85_RS05305 1187382..1188020 + 639 WP_199250217.1 hypothetical protein -
HEQ85_RS05310 1188041..1188505 + 465 WP_199248616.1 DUF29 domain-containing protein -
HEQ85_RS05315 1188704..1189195 + 492 Protein_1042 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(1-67)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 68 a.a.        Molecular weight: 7972.29 Da        Isoelectric Point: 10.0964

>T153698 WP_199248613.1 NZ_CP051168:1184742-1184945 [[Phormidium] sp. ETS-05]
MKISFTEASWSDYLWLQANEQKLLKRVNLLIKDIIITPFDWIGKPEPLKGNLSGYWSRRINTEHRLV

Download         Length: 204 bp

>T153698 NZ_CP067045:347818-348186 [Klebsiella pneumoniae]
ATGACGCTGCAGATTATCTCAGCGGAAGAGATAATACAGTTTCACGACAGGCTGCTCCGCGTCACGCCTGGCGTTGCCGG
TATGCCCGATCCGGGGCGTGCCGAAGCGATAATGTATAGGGTGCTAAACAAAATTGAATATGAAGGTGTGACAGACGTGT
GGCGACTCGCTGCGATGCATCTGCTGGCGATTTCTCGCGGTCATATATTTAATGATGGTAATAAGCGTACGGCACTGTTT
ATCACCCTGCTTTTTTTAAAGCGAAATGGAATTATATTGCCAGCGAATCCAGACTTCGTCGGCATGACCGTCGAGGCAGC
AGCAGGGCAACTTACCCTGGAACAGATTGTCGCGCGTTTGCGTGGATGA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9485.76 Da        Isoelectric Point: 4.3085

>AT153698 WP_199248612.1 NZ_CP051168:1184491-1184745 [[Phormidium] sp. ETS-05]
MKAITSNQAKQQLDEIIEQVILDVEPTILCSDRGQQAVLMSLDEFNSWQETIYLLSNPANAEHLLESIKQAKSGKKSVRE
LLDE

Download         Length: 255 bp

>AT153698 NZ_CP067045:347600-347821 [Klebsiella pneumoniae]
ATGAGAACGGTTAACTATAGCGAAGCCCGGCAAAATCTGGCCGATGTGCTGGAAAGCGCAGTGACAGGTGTACCTGTGAC
CATTACCCGTCGTGGGCATAAATCTGCAGTCATCATTAGTGCAGAAGAGTTTGAACGCTACCAGGCGGCCAGAATGGATG
ATGAGTTCGCGGCTATCATGGCGGTTCATGGTGATGAGATCAGGGAGCTTGCGGATAAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References