153696

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) TacT2-ataR/GNAT-DUF1778
Location 305215..306026 Replicon chromosome
Accession NZ_CP051168
Organism [Phormidium] sp. ETS-05

Toxin (Protein)


Gene name TacT2 Uniprot ID -
Locus tag HEQ85_RS01495 Protein ID WP_199248008.1
Coordinates 305502..306026 (+) Length 175 a.a.

Antitoxin (Protein)


Gene name ataR Uniprot ID -
Locus tag HEQ85_RS01490 Protein ID WP_199248007.1
Coordinates 305215..305511 (+) Length 99 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HEQ85_RS01470 300727..302070 - 1344 WP_199250120.1 MATE family efflux transporter -
HEQ85_RS01475 302536..302853 + 318 WP_199248005.1 hypothetical protein -
HEQ85_RS01480 302956..303630 + 675 WP_199248006.1 hypothetical protein -
HEQ85_RS01485 303900..304960 - 1061 Protein_293 photosystem II q(b) protein -
HEQ85_RS01490 305215..305511 + 297 WP_199248007.1 DUF1778 domain-containing protein Antitoxin
HEQ85_RS01495 305502..306026 + 525 WP_199248008.1 GNAT family N-acetyltransferase Toxin
HEQ85_RS01500 306186..307028 + 843 WP_199248009.1 Uma2 family endonuclease -
HEQ85_RS01505 307327..307635 + 309 WP_199248010.1 nucleotidyltransferase domain-containing protein -
HEQ85_RS01510 307688..307888 + 201 WP_199250121.1 HEPN domain-containing protein -
HEQ85_RS01515 308129..310288 - 2160 WP_199248011.1 M23 family metallopeptidase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(74-150)

Antitoxin

Vibrio phage ICP1, Orf50

(17-92)


Sequences

Toxin        


Download         Length: 175 a.a.        Molecular weight: 19056.99 Da        Isoelectric Point: 8.6959

>T153696 WP_199248008.1 NZ_CP051168:305502-306026 [[Phormidium] sp. ETS-05]
VGLESDKQQLLPPEKLNSSHQIDNFDSGNSQLNDWLKRRALKNESGGASRTYVVCVGQVVIAYYCLANGAVAQTIATGKV
RRNMPNPIPVMVIGRLAVDRHWQSQGIGRALLRDAILRTLQAAEIAGIRAILVHAISEEAKQFYEKCGFTASPIEPMTLM
VTVDEARYALGLLP

Download         Length: 525 bp

>T153696 NZ_CP067043:c647306-646956 [Bacillus velezensis]
TTGATTGTAAAGCGCGGCGATGTTTATTTTGCTGATTTATCTCCTGTTGTTGGCTCAGAGCAAGGCGGCGTACGCCCGGT
TTTAGTGATCCAGAATGATATCGGAAATCGCTTTAGCCCGACTGCTATTGTTGCAGCCATAACAGCCCAAATACAGAAAG
CGAAATTACCAACCCACGTCGAAATTGATGCAAAACGCTACGGTTTTGAAAGAGATTCCGTTATTTTGCTGGAGCAAATT
CGGACGATTGACAAGCAAAGATTAACGGATAAAATAACTCATCTGGATGATGAAATGATGGATAAGGTTGATGAAGCCCT
GCAAATCAGTTTGGCACTCATTGATTTTTAG

Antitoxin


Download         Length: 99 a.a.        Molecular weight: 11181.52 Da        Isoelectric Point: 4.6437

>AT153696 WP_199248007.1 NZ_CP051168:305215-305511 [[Phormidium] sp. ETS-05]
MSDSDLEASTNQTRDVKINIRAKQGQRDLIDTAAQLQGKSRSEFMLESAYQRAQEVILDQTFFGLDEAKFQQFIELLDAP
PAQNEKLHALIRTKAPWD

Download         Length: 297 bp

>AT153696 NZ_CP067043:c647593-647312 [Bacillus velezensis]
TTGTCTGAATCCAGCGCAAGAACCGAAATGAAAATCAGCTTGCCCGAAAACTTAGTAGCTGAATTGGATGGTGTAGCGAT
GCGGGAGAAACGAAGCAGAAACGAACTGATATCACAAGCAGTGAGAGCGTATGTCAGCGAACGGACAACTCGCCATAACC
GTGATTTGATGAGACGCGGGTATATGGAAATGGCGAAAATCAACTTGAATATCTCTTCTGAGGCTCACTATGCTGAGTGC
GAAGCAGAAACGACCGTTGAGCGCTTAGTCAGCGGAGGATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References