Detailed information of TA system TA153694

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/RelE(toxin)
• Location: 101515..102124
• Replicon: chromosome
• Accession: NZ_CP051168
• Organism: [Phormidium] sp. ETS-05

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: HEQ85_RS00570
• Protein ID: WP_199247856.1
• Coordinates: 101515..101880 (-)
• Length: 122 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: HEQ85_RS00575
• Protein ID: WP_199247857.1
• Coordinates: 101870..102124 (-)
• Length: 85 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
HEQ85_RS00545	97480..98106	+	627	WP_199247852.1	hypothetical protein	-
HEQ85_RS00550	98292..98543	+	252	WP_199247853.1	hypothetical protein	-
HEQ85_RS00555	98556..99590	-	1035	WP_199250100.1	CHAT domain-containing protein	-
HEQ85_RS00560	99530..100921	-	1392	WP_199247854.1	tetratricopeptide repeat protein	-
HEQ85_RS00565	101046..101240	-	195	WP_199247855.1	DUF433 domain-containing protein	-
HEQ85_RS00570	101515..101880	-	366	WP_199247856.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
HEQ85_RS00575	101870..102124	-	255	WP_199247857.1	hypothetical protein	Antitoxin
HEQ85_RS00580	102295..102504	-	210	WP_199250101.1	hypothetical protein	-
HEQ85_RS00585	102573..103196	-	624	WP_199247858.1	hypothetical protein	-
HEQ85_RS00590	103472..104329	+	858	WP_199247859.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin HigB-2 (59-111)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 122 a.a.
• Molecular weight: 13873.95 Da
• Isoelectric Point: 9.2054

>T153694 WP_199247856.1 NZ_CP051168:c101880-101515 [[Phormidium] sp. ETS-05]
MLNDKPLVQIDLTPQYKRNLRDLSKKYRRIRLDTQPIIEELQRGNFTGDRLAGMGEDYLIFKVRVKNTDIQKGKSGGYRM
IYQVESPTSVLLLTIYAKSDVADISPNEISSILAEFYGESL

Nucleotide

• Length: 366 bp

>T153694 NZ_CP067042:c474870-474583 [Lacticaseibacillus rhamnosus]
ATGATGTTGACGATTAATCGCACGCGCACTTTCAAACGACAATTTAAACATCTTCTTAGGCAAGGTAAAGATATGACGAA
ACTTGCAACTGCAATTGATACTTTGCAGCGTCAAGATCGTGTAAAATTAGCTTCTTTACACGACCATGCTTTAAAGGGTG
CTCACAGCGGCGAACGAGCATTGCGTGTTGCTCCTGATTGGCTTCTCGTTTATAAAGTCGATGCTGAAGCGTTAATTTTA
ATGCTTCTTGCAACAGGCACACACCGCGATACATTGAACATTGAGTAA

Antitoxin

Protein

• Length: 85 a.a.
• Molecular weight: 9320.63 Da
• Isoelectric Point: 4.1532

>AT153694 WP_199247857.1 NZ_CP051168:c102124-101870 [[Phormidium] sp. ETS-05]
MKAVEVTGTLDEKGQLSLDQAIENCAPSRVRVIVLFPEVMEGEEIDPDDTPVEEIKASLRRALQEAKAGKRIPLSQMWEG
LDVE

Nucleotide

• Length: 255 bp

>AT153694 NZ_CP067042:c475126-474854 [Lacticaseibacillus rhamnosus]
ATGGAAACAAAATCCCGTATCAGCGTGCGAATTGATACCAAAACCAAAGAACGGGCTCTCCATGTCCTCAATAGCATGGG
ACTAGATATGTCCTCAGCTATTAACATGTATTTGAAACGCATTGGTGACACTGGTGAGTTGCCATTTACACCTGAAATGT
CGTTCGCCGATCAGCTTCAAGCTGCAGAAGCTGATGTTAAAGCGGGACGAACTAAGAGCTTCAAGACCGTTGATGCCCTG
ATGAAGGATTTATACAATGATGTTGACGATTAA