Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC(toxin)
Location 256358..256824 Replicon chromosome
Accession NZ_CP051167
Organism Oxynema sp. AP17

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag HCG48_RS01115 Protein ID WP_168571679.1
Coordinates 256585..256824 (+) Length 80 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag HCG48_RS01110 Protein ID WP_210437141.1
Coordinates 256358..256585 (+) Length 76 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HCG48_RS01075 252272..252853 - 582 WP_168571678.1 sulfotransferase domain-containing protein -
HCG48_RS01080 253208..253747 + 540 WP_168567509.1 Uma2 family endonuclease -
HCG48_RS01085 253916..254095 - 180 Protein_212 hypothetical protein -
HCG48_RS01090 254177..254497 - 321 WP_210437139.1 hypothetical protein -
HCG48_RS01095 254681..254989 - 309 WP_210437140.1 hypothetical protein -
HCG48_RS01100 255173..255562 - 390 Protein_215 glycosyl transferase family 4 -
HCG48_RS01110 256358..256585 + 228 WP_210437141.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
HCG48_RS01115 256585..256824 + 240 WP_168571679.1 type II toxin-antitoxin system VapC family toxin Toxin
HCG48_RS01120 256800..257321 - 522 WP_168567511.1 hypothetical protein -
HCG48_RS01125 257402..257848 - 447 WP_168567512.1 DUF29 domain-containing protein -
HCG48_RS01130 258018..259145 - 1128 WP_168567513.1 aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme -
HCG48_RS01135 259152..259784 - 633 WP_168567514.1 acetyltransferase -
HCG48_RS01140 259797..260438 - 642 WP_168567515.1 sugar transferase -
HCG48_RS01145 260449..261660 - 1212 WP_168567516.1 glycosyltransferase family 4 protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Antitoxin VapB-like

(1-74)


Sequences

Toxin        


Download         Length: 80 a.a.        Molecular weight: 8531.71 Da        Isoelectric Point: 4.5898

>T153690 WP_168571679.1 NZ_CP051167:256585-256824 [Oxynema sp. AP17]
MVIDTSAIAAILFDEPERADFISKNQVDFAALAWRNYGKGRHPAGLNCGDCFAYALAKATGEPLLFKGADFSQTDIAMC

Download         Length: 240 bp

>T153690 NZ_CP067037:c606929-606594 [Agrobacterium fabrum]
GTGACGAATAAGAAAGATCACGGAAAAGACGCGGCATTGAAGCGAGCCACCCTGCCGCGCAGGTCGGATTTCACCAAGCA
ATTTATCAAAGACTGGCAACGGCTGAACAATTCCGGGCGTTACGACATGGTGAGACTGAAGGAGATCATGCTCCTTCTTA
TCGCCAACGGCGCGCCGTTACCGACGCAGTTTCGTGACCATGAACTGACCGGAGACTGGCGCGATCACCGGGAATGCCAT
GTCGGCGGGGATTTTCTGTTGATCTACACAGTCGATGAGAAGCAGAACCTTCTCATCTTCACCCGCGCGGGAACGCACGC
CGAGCTTTTCAGGTAA

Antitoxin


Download         Length: 76 a.a.        Molecular weight: 8313.53 Da        Isoelectric Point: 6.9791

>AT153690 WP_210437141.1 NZ_CP051167:256358-256585 [Oxynema sp. AP17]
MTKELANLTGLSLTAAVKMAVERALIQARAEHQRPKSRSIERNLTEISLRCAALPDGDRRSMDEILGYDEFGLPS

Download         Length: 228 bp

>AT153690 NZ_CP067037:c607201-606926 [Agrobacterium fabrum]
ATGACCGCAAATGCTTATGTAAGAGCGCGCATCGATCAGACACTCAAGGACGACGCGACGGCCGTGCTGGACCGCCTGGG
ACTGACTGTTTCAGATGTCATGCGAATGATGCTGACGCGCATTGCCCGAGAAAAAGCTCTGCCGATAGAACTGACACAAC
CAAACGCTGAAACCCTTGCCGCGATTGAAGAAGCGCGCGCCATCGCGGCGGCCGGGCGCAATCGTTTCGGCACGTCTGAA
GCCTTGTTTGAGGCGCTGGACGCTGGCAAACGGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References