Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | VII | Classification (family/domain) | HepT-MntA/HepT(toxin) |
Location | 1500071..1500875 | Replicon | chromosome |
Accession | NZ_CP051162 | ||
Organism | Geobacillus subterraneus strain CPW16 |
Toxin (Protein)
Gene name | hepT | Uniprot ID | - |
Locus tag | HF500_RS07580 | Protein ID | WP_168368306.1 |
Coordinates | 1500071..1500490 (-) | Length | 140 a.a. |
Antitoxin (Protein)
Gene name | mntA | Uniprot ID | - |
Locus tag | HF500_RS07585 | Protein ID | WP_210436925.1 |
Coordinates | 1500480..1500875 (-) | Length | 132 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
HF500_RS07555 | 1495206..1496900 | + | 1695 | WP_168369010.1 | M3 family oligoendopeptidase | - |
HF500_RS07560 | 1496980..1497495 | + | 516 | WP_020959098.1 | GNAT family N-acetyltransferase | - |
HF500_RS07565 | 1497628..1498296 | + | 669 | WP_168368304.1 | ABC transporter ATP-binding protein | - |
HF500_RS07570 | 1498353..1499378 | + | 1026 | WP_020959100.1 | ABC transporter permease | - |
HF500_RS07575 | 1499390..1500043 | + | 654 | WP_168368305.1 | TetR/AcrR family transcriptional regulator | - |
HF500_RS07580 | 1500071..1500490 | - | 420 | WP_168368306.1 | DUF86 domain-containing protein | Toxin |
HF500_RS07585 | 1500480..1500875 | - | 396 | WP_210436925.1 | nucleotidyltransferase domain-containing protein | Antitoxin |
HF500_RS07590 | 1500938..1501096 | + | 159 | WP_156487387.1 | hypothetical protein | - |
HF500_RS07595 | 1501074..1501301 | + | 228 | Protein_1432 | beta-glucuronidase | - |
HF500_RS07600 | 1501325..1501630 | + | 306 | WP_174539025.1 | hypothetical protein | - |
HF500_RS07605 | 1501652..1502145 | + | 494 | Protein_1434 | SDR family oxidoreductase | - |
HF500_RS07610 | 1502173..1502976 | + | 804 | WP_168368308.1 | ATP-dependent sacrificial sulfur transferase LarE | - |
HF500_RS07615 | 1503124..1503393 | + | 270 | WP_063166490.1 | hypothetical protein | - |
HF500_RS07620 | 1503398..1504147 | + | 750 | WP_168369011.1 | nickel pincer cofactor biosynthesis protein LarB | - |
HF500_RS07625 | 1504153..1505067 | + | 915 | WP_020959114.1 | LarC family nickel insertion protein | - |
HF500_RS07630 | 1505093..1505575 | + | 483 | WP_020959115.1 | DUF111 family protein | - |
HF500_RS07635 | 1505586..1505837 | + | 252 | WP_063166488.1 | hypothetical protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 140 a.a. Molecular weight: 16015.44 Da Isoelectric Point: 7.3515
>T153672 WP_168368306.1 NZ_CP051162:c1500490-1500071 [Geobacillus subterraneus]
MKSDVIFNKISVIERCLKRIREEYNDNPKNLQNYTKQDSIVLNLQRACEACIDLAMHIVAEQKFGLPQHSRDAFALLEEH
GVISPSVSKKMKAMIGFRNIAVHDYQQLNLGIVQAIVEQHLDDFKQFAEAILRYAKENN
MKSDVIFNKISVIERCLKRIREEYNDNPKNLQNYTKQDSIVLNLQRACEACIDLAMHIVAEQKFGLPQHSRDAFALLEEH
GVISPSVSKKMKAMIGFRNIAVHDYQQLNLGIVQAIVEQHLDDFKQFAEAILRYAKENN
Download Length: 420 bp
>T153672 NZ_CP067022:c5642912-5642730 [Pseudomonas cannabina pv. alisalensis]
ATGAAGTGCAGCGAGTTTCGGCGATGGTTGCAGGCTCAAGGCGCTGAGTTCAGGGCGGCCAAGGGTAGTCATTTCAAGGT
TTACCTGAATGGTAAGGCAACCATCTTTGCAGATCATGGCAGCAAAGAAATGCACGAAGGGTTACGCAAGTCGATCATCA
AGCAGCTCGGCCTTAAGGATTGA
ATGAAGTGCAGCGAGTTTCGGCGATGGTTGCAGGCTCAAGGCGCTGAGTTCAGGGCGGCCAAGGGTAGTCATTTCAAGGT
TTACCTGAATGGTAAGGCAACCATCTTTGCAGATCATGGCAGCAAAGAAATGCACGAAGGGTTACGCAAGTCGATCATCA
AGCAGCTCGGCCTTAAGGATTGA
Antitoxin
Download Length: 132 a.a. Molecular weight: 14785.97 Da Isoelectric Point: 4.5491
>AT153672 WP_210436925.1 NZ_CP051162:c1500875-1500480 [Geobacillus subterraneus]
METVIIQTLRPVLDPFVIYLFGSAARGALRPDSDVDIAFISEGEPYDPYELFLLAGQLADKLGRDVDLVDLRRASTVFQA
QVVSTGKAIDCRDERKRAEFEMKTLKMYVKLNEERAPVLQQIAESGTIYEK
METVIIQTLRPVLDPFVIYLFGSAARGALRPDSDVDIAFISEGEPYDPYELFLLAGQLADKLGRDVDLVDLRRASTVFQA
QVVSTGKAIDCRDERKRAEFEMKTLKMYVKLNEERAPVLQQIAESGTIYEK
Download Length: 396 bp
>AT153672 NZ_CP067022:c5642698-5642273 [Pseudomonas cannabina pv. alisalensis]
ATGTATCAATATCCATTGGATCAGCATCTGGAGCCGACAGGCGTTTGGCTGTCGTGTCCAGACATTCCCGAAATGAGCGC
CTCTGGCGACACCCTTACTGAAGCATTGAGCGAAGCTCTTGACGGCATGGAATCGGCTCTATCGCTCTACGTCGAGCAGC
GTCGCAAGATTCCCCAGGCCTCAGTCGTACCCGGTCATGAACTGTTAATGCGTTTGCCTGCGCTGACTGTTGCCAAAATC
ATGCTGTGGAATAGCTTGTTGGAAGAGGGCGTTAGTCGTGCTGAGCTAGCGCGTCGCCTGGGTTGCACGCGGCAAGTGGT
GTATCGGCTTGTGGACTTTCTGCATGCCTCGAAAATCGAGCAGGTGGAGCGAGCGCTGGCTGAGCTTGGTCGGCGTATTA
CGTTGAGTATTGAGCGGGCCGCTTGA
ATGTATCAATATCCATTGGATCAGCATCTGGAGCCGACAGGCGTTTGGCTGTCGTGTCCAGACATTCCCGAAATGAGCGC
CTCTGGCGACACCCTTACTGAAGCATTGAGCGAAGCTCTTGACGGCATGGAATCGGCTCTATCGCTCTACGTCGAGCAGC
GTCGCAAGATTCCCCAGGCCTCAGTCGTACCCGGTCATGAACTGTTAATGCGTTTGCCTGCGCTGACTGTTGCCAAAATC
ATGCTGTGGAATAGCTTGTTGGAAGAGGGCGTTAGTCGTGCTGAGCTAGCGCGTCGCCTGGGTTGCACGCGGCAAGTGGT
GTATCGGCTTGTGGACTTTCTGCATGCCTCGAAAATCGAGCAGGTGGAGCGAGCGCTGGCTGAGCTTGGTCGGCGTATTA
CGTTGAGTATTGAGCGGGCCGCTTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|
Antitoxin
Source | ID | Structure |
---|