Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1836314..1836459 Replicon chromosome
Accession NZ_CP051161
Organism Klebsiella pneumoniae strain 16BU137

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1836350..1836452 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1836314..1836459 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HF572_RS08860 1831444..1833504 + 2061 WP_004151449.1 oligopeptidase B -
HF572_RS08865 1833508..1834167 - 660 WP_002911407.1 exodeoxyribonuclease X -
HF572_RS08870 1834246..1834476 - 231 WP_002911406.1 DNA polymerase III subunit theta -
HF572_RS08875 1834589..1834963 + 375 WP_004151448.1 CopC domain-containing protein YobA -
HF572_RS08880 1834967..1835836 + 870 WP_020956678.1 copper homeostasis membrane protein CopD -
HF572_RS08885 1835853..1836191 + 339 WP_002911404.1 YebY family protein -
- 1836314..1836459 - 146 - - Antitoxin
- 1836350..1836452 + 103 - - Toxin
HF572_RS08890 1836827..1836970 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
HF572_RS08895 1837075..1838043 - 969 WP_004151446.1 VirK/YbjX family protein -
HF572_RS08900 1838200..1838853 + 654 WP_020802220.1 protein-serine/threonine phosphatase -
HF572_RS08905 1838850..1839041 - 192 WP_002911395.1 YebW family protein -
HF572_RS08910 1839139..1839378 - 240 WP_002911393.1 YebV family protein -
HF572_RS08915 1839494..1840927 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T153656 NZ_CP051161:1836350-1836452 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT153656 NZ_CP051161:c1836459-1836314 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References