Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1994943..1995088 Replicon chromosome
Accession NZ_CP051160
Organism Klebsiella pneumoniae strain KP20191015

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1994979..1995081 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1994943..1995088 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HF573_RS09890 1990073..1992133 + 2061 WP_004151449.1 oligopeptidase B -
HF573_RS09895 1992137..1992796 - 660 WP_032425085.1 exodeoxyribonuclease X -
HF573_RS09900 1992875..1993105 - 231 WP_002911406.1 DNA polymerase III subunit theta -
HF573_RS09905 1993218..1993592 + 375 WP_004151448.1 CopC domain-containing protein YobA -
HF573_RS09910 1993596..1994465 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
HF573_RS09915 1994482..1994820 + 339 WP_016529031.1 YebY family protein -
- 1994943..1995088 - 146 - - Antitoxin
- 1994979..1995081 + 103 - - Toxin
HF573_RS09920 1995456..1995599 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
HF573_RS09925 1995704..1996672 - 969 WP_004151446.1 VirK/YbjX family protein -
HF573_RS09930 1996829..1997482 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
HF573_RS09935 1997479..1997670 - 192 WP_002911395.1 YebW family protein -
HF573_RS09940 1997768..1998007 - 240 WP_002911393.1 YebV family protein -
HF573_RS09945 1998123..1999556 - 1434 WP_032411854.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T153638 NZ_CP051160:1994979-1995081 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT153638 NZ_CP051160:c1995088-1994943 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References