Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1057592..1057737 Replicon chromosome
Accession NZ_CP051159
Organism Klebsiella pneumoniae strain 19PDR22

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1057599..1057701 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1057592..1057737 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HF574_RS05420 1053124..1054557 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
HF574_RS05425 1054673..1054912 + 240 WP_002911393.1 YebV family protein -
HF574_RS05430 1055010..1055201 + 192 WP_002911395.1 YebW family protein -
HF574_RS05435 1055198..1055851 - 654 WP_004180432.1 protein-serine/threonine phosphatase -
HF574_RS05440 1056008..1056976 + 969 WP_004151446.1 VirK/YbjX family protein -
HF574_RS05445 1057081..1057224 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 1057592..1057737 + 146 - - Antitoxin
- 1057599..1057701 - 103 - - Toxin
HF574_RS05450 1057860..1058198 - 339 WP_002911404.1 YebY family protein -
HF574_RS05455 1058215..1059084 - 870 WP_062955019.1 copper homeostasis membrane protein CopD -
HF574_RS05460 1059088..1059462 - 375 WP_004151448.1 CopC domain-containing protein YobA -
HF574_RS05465 1059575..1059805 + 231 WP_002911406.1 DNA polymerase III subunit theta -
HF574_RS05470 1059884..1060543 + 660 WP_002911407.1 exodeoxyribonuclease X -
HF574_RS05475 1060547..1062607 - 2061 WP_004151449.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T153613 NZ_CP051159:c1057701-1057599 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT153613 NZ_CP051159:1057592-1057737 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References