Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ-DinJ
Location 288912..289477 Replicon chromosome
Accession NZ_CP051153
Organism Treponema vincentii strain OMZ 862

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag E4N73_RS01580 Protein ID WP_253807678.1
Coordinates 288912..289184 (-) Length 91 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag E4N73_RS01585 Protein ID WP_253807679.1
Coordinates 289181..289477 (-) Length 99 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
E4N73_RS01570 (E4N73_01575) 285551..286303 + 753 WP_006188448.1 lysophospholipid acyltransferase family protein -
E4N73_RS01575 (E4N73_01580) 286333..288318 - 1986 WP_253807677.1 exodeoxyribonuclease V subunit gamma -
E4N73_RS01580 (E4N73_01585) 288912..289184 - 273 WP_253807678.1 type II toxin-antitoxin system YafQ family toxin Toxin
E4N73_RS01585 (E4N73_01590) 289181..289477 - 297 WP_253807679.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
E4N73_RS01590 (E4N73_01595) 289651..290112 + 462 WP_253807680.1 hypothetical protein -
E4N73_RS01595 (E4N73_01600) 290223..291605 - 1383 WP_253807681.1 radical SAM protein -
E4N73_RS01600 (E4N73_01605) 292219..293058 - 840 WP_253807682.1 ISAs1 family transposase -
E4N73_RS01605 293171..293380 - 210 Protein_318 transposase family protein -
E4N73_RS01610 (E4N73_01610) 293659..293883 + 225 WP_253807683.1 hypothetical protein -
E4N73_RS01615 (E4N73_01615) 293880..294266 + 387 WP_253807684.1 PIN domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(3-90)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-90)


Sequences

Toxin        


Download         Length: 91 a.a.        Molecular weight: 10232.84 Da        Isoelectric Point: 9.5995

>T153584 WP_253807678.1 NZ_CP051153:c289184-288912 [Treponema vincentii]
MMELVTTGAFRKDYKRAKKRGLDMSLLESVINKLLAGVALEERHRDHALSGNYTGFRECHIQPDWLLIYAVNKSQLILTA
SRTGTHADLF

Download         Length: 273 bp

>T153584 NZ_CP066979:3416896-3417387 [Xanthomonas campestris pv. campestris]
ATGACGGTATCGGCGCCGGAACCGCTGACAGCGCATCACCGGGTCGAACCGTTCGCATCGGGCGTGGAGAGCCTGGATCA
CTGGCTCAAGCGCCGCGCCCTGAAAAATCAGGCAACCGGTGCGTCACGGACCTTCGTTGCCTGCGAGGATGACCGCGTGG
TGGCCTATTACGCCCTGGCGTCGAGTGCGGTCGCCGTGGACGCGACGCCCGGCCGCTTCCGTCGCAACATGCCGGACCCG
ATCCCCGTGGTGGTGCTTGGGAGGCTTGCTGTTGACCAATCCCTGCATGGCAGAGGTTTTGGCCGCGCCCTGATGCAGGA
TGCTGGCAAGCGCATCCTGCATGCGGCCGACACCATCGGCATTCGCGGGCTGCTCGTGCATGCGCTCTCGGCGGACGCTA
AGGCGTTTTACGAGCGCATCGGCTTCGAACCTTCCCCGCTGGATCCCATGGTGCTGGTCGTCACGCTGGAAGACCTGAAA
GCCAGTCTGTGA

Antitoxin


Download         Length: 99 a.a.        Molecular weight: 10699.28 Da        Isoelectric Point: 5.8598

>AT153584 WP_253807679.1 NZ_CP051153:c289477-289181 [Treponema vincentii]
MAKTANITIRIDPETKTSAEQLFSSFGITVTDAISIFLHKSIMEGGLPFEVKQPRFNAETEAAIEEARGIIAGKIPAKRY
GSARALFNELDTEITAKL

Download         Length: 297 bp

>AT153584 NZ_CP066979:3416609-3416899 [Xanthomonas campestris pv. campestris]
ATGTCCACACCCAACACTACGCCTGGCAAGCGCGAAACCTTGAATCTCCGCATCAAGCCGGAGGAGCGCAGCCTGATCGA
CCGGGCCGCCAAGGCGCGCGGGAAGAACCGCACCGATTTCATGCTGGACGCAGCGCGCTCGGCGGCCGAGGAAGCCTTGC
TGGACCAGACCCTCATCACGGCCAGCCCGGACGCCTACGCCGCCTTTTTGGCACGGCTGGACATGCCGCCGCAGCCGAAC
GCGCGCCTGCGCAAGACGATGCAGACGCCCGCTCCTTGGGAGAAGGCATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References