153577

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) BrnTA/BrnT-BrnA
Location 1269757..1270318 Replicon chromosome
Accession NZ_CP051148
Organism Treponema vincentii strain OMZ 861

Toxin (Protein)


Gene name brnT Uniprot ID -
Locus tag E4N72_RS05895 Protein ID WP_253806802.1
Coordinates 1269757..1270059 (+) Length 101 a.a.

Antitoxin (Protein)


Gene name brnA Uniprot ID -
Locus tag E4N72_RS05900 Protein ID WP_253814264.1
Coordinates 1270064..1270318 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
E4N72_RS05870 (E4N72_05920) 1264843..1266495 - 1653 WP_253814257.1 hypothetical protein -
E4N72_RS05875 (E4N72_05925) 1266816..1268549 - 1734 WP_253814259.1 ParB/RepB/Spo0J family partition protein -
E4N72_RS05880 (E4N72_05930) 1268528..1268800 - 273 WP_253814261.1 hypothetical protein -
E4N72_RS05885 (E4N72_05935) 1269030..1269227 - 198 WP_253673727.1 hypothetical protein -
E4N72_RS05890 (E4N72_05940) 1269257..1269484 - 228 WP_253814262.1 hypothetical protein -
E4N72_RS05895 (E4N72_05945) 1269757..1270059 + 303 WP_253806802.1 BrnT family toxin Toxin
E4N72_RS05900 (E4N72_05950) 1270064..1270318 + 255 WP_253814264.1 BrnA antitoxin family protein Antitoxin
E4N72_RS05905 (E4N72_05955) 1270735..1271127 + 393 WP_253806800.1 hypothetical protein -
E4N72_RS05910 (E4N72_05960) 1271152..1271415 + 264 WP_253806799.1 hypothetical protein -
E4N72_RS05915 (E4N72_05965) 1271466..1271876 - 411 WP_253814266.1 GNAT family N-acetyltransferase -
E4N72_RS05920 (E4N72_05970) 1272041..1273885 + 1845 WP_253814268.1 hypothetical protein -
E4N72_RS05925 (E4N72_05980) 1273960..1275003 - 1044 WP_253814270.1 GNAT family N-acetyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease toxin, BrnT, of type II toxin-antitoxin system

(8-86)

Antitoxin

BrnA antitoxin of type II toxin-antitoxin system

(23-73)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11663.10 Da        Isoelectric Point: 4.8945

>T153577 WP_253806802.1 NZ_CP051148:1269757-1270059 [Treponema vincentii]
MNNELFEWDNEKNTINKQKHRIGFEEAILVFDDPFHIELYDTTHSDKEDRFVAIGTVLNILIVVVVYTERNGKVRIISAR
PATNKEKELYYDAVNNTFGS

Download         Length: 303 bp

>T153577 NZ_CP066975:c4607948-4607796 [Xanthomonas campestris pv. campestris]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTCTCGGCCGGCATGATGACTGGCTGTAACACCATGGCTGGTGC
CGGAAAGGACATGCAGGGTGCGGGTGACAAGGTCGAGAAGACCGCCGACAAATGCAGCGACGGTAAGTGCTAA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9690.26 Da        Isoelectric Point: 10.1756

>AT153577 WP_253814264.1 NZ_CP051148:1270064-1270318 [Treponema vincentii]
MLTQERIKQLKTLAVQPVDTSDIPELTQEDFLKMYRPIKQPLSIRLDSDIIVWLKSYGKGYQSRINTILRNAMAAEKQAA
QQRG

Download         Length: 255 bp

>AT153577 NZ_CP066975:c4607719-4607585 [Xanthomonas campestris pv. campestris]
ATGAAGCGTGCAATTGCATTGTTGGTGCTGTCGATGTTGTCGGTTGGAATGCTGGCGGGTTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGCAGGGCGCTGGCGAGAAGGTGGAAGACGCCGCGCGCAAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References