Detailed information of TA system TA153566

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): /RES-TIGR02293
• Location: 3818292..3819205
• Replicon: chromosome
• Accession: NZ_CP051132
• Organism: Enterobacter hormaechei strain AMS-38

Toxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: HDB52_RS18275
• Protein ID: WP_032647883.1
• Coordinates: 3818292..3818765 (-)
• Length: 158 a.a.

Antitoxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: HDB52_RS18280
• Protein ID: WP_023296216.1
• Coordinates: 3818762..3819205 (-)
• Length: 148 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
HDB52_RS18255	3814451..3815761	+	1311	WP_032647879.1	type I-F CRISPR-associated protein Csy1	-
HDB52_RS18260	3815758..3816693	+	936	WP_032647880.1	type I-F CRISPR-associated protein Csy2	-
HDB52_RS18265	3816707..3817705	+	999	WP_032647881.1	type I-F CRISPR-associated protein Csy3	-
HDB52_RS18270	3817715..3818269	+	555	WP_032647882.1	type I-F CRISPR-associated endoribonuclease Cas6/Csy4	-
HDB52_RS18275	3818292..3818765	-	474	WP_032647883.1	RES domain-containing protein	Toxin
HDB52_RS18280	3818762..3819205	-	444	WP_023296216.1	DUF2384 domain-containing protein	Antitoxin
HDB52_RS18285	3820303..3820521	-	219	WP_002211347.1	translation initiation factor IF-1	-
HDB52_RS18290	3820806..3821510	-	705	WP_032647884.1	leucyl/phenylalanyl-tRNA--protein transferase	-
HDB52_RS18295	3821556..3823277	-	1722	WP_032647885.1	cysteine/glutathione ABC transporter ATP-binding protein/permease CydC	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• RES domain (3-147)

Antitoxin

• Antitoxin Xre (15-147)

Sequences

Toxin

Protein

• Length: 158 a.a.
• Molecular weight: 17569.96 Da
• Isoelectric Point: 5.5555

>T153566 WP_032647883.1 NZ_CP051132:c3818765-3818292 [Enterobacter hormaechei]
MIFYRLVTGRFASEAWSGSGANQYGGRWNHKGHPAVYVSTSISLASLEILVHVRKDTVLNQYQLFSINIPDDQIDYLDKA
WLPEDWQENPAPVSTMDLGTGWLQANSALALILPSCIIPYENNAILNPLHPAFRKALNSVELLPFNFDTRLAEKTAP

Nucleotide

• Length: 474 bp

>T153566 NZ_CP066969:431601-431735 [Xanthomonas campestris]
ATGAAGCGTGCAATTGCATTGTTGGTGCTGTCGATGTTGTCGGTTGGAATGCTGGCGGGTTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGCAGGGCGCTGGCGAGAAGGTGGAAGACGCCGCGCGCAAGTGA

Antitoxin

Protein

• Length: 148 a.a.
• Molecular weight: 16512.81 Da
• Isoelectric Point: 6.4819

>AT153566 WP_023296216.1 NZ_CP051132:c3819205-3818762 [Enterobacter hormaechei]
MRTWVPAQRPADNTLWRYAGLPASRGMRLIEYLNQGLPVSVLDNIHEWTDMSKAEILRVTGINERNVARRKSTGRTLTPD
ESERVARFVRVLDAAVDYFGSKEEAWNWLQLPVRGLGNVAPVDLIATETGALEVTDLIGRLEHGVFA

Nucleotide

• Length: 444 bp

>AT153566 NZ_CP066969:431372-431524 [Xanthomonas campestris]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTCTCGGCCGGCATGATGACTGGCTGTAACACCATGGCTGGTGC
CGGAAAGGACATGCAGGGTGCGGGTGACAAGGTCGAGAAGACCGCCGACAAATGCAGCGACGGTAAGTGCTGA