Detailed information of TA system TA153548

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): /SpoIISA(toxin)
• Location: 2806890..2807868
• Replicon: chromosome
• Accession: NZ_CP051013
• Organism: Bacillus tropicus strain LM1212-DB

Toxin (Protein)

• Gene name: spoIISA
• Uniprot ID: -
• Locus tag: HCM98_RS14535
• Protein ID: WP_029438355.1
• Coordinates: 2807131..2807868 (-)
• Length: 246 a.a.

Antitoxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: HCM98_RS14530
• Protein ID: WP_029438356.1
• Coordinates: 2806890..2807018 (-)
• Length: 43 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
HCM98_RS14510 (HCM98_14535)	2802849..2803508	-	660	WP_029438360.1	CatB-related O-acetyltransferase	-
HCM98_RS14515 (HCM98_14540)	2803962..2804432	+	471	WP_029438359.1	DUF5065 family protein	-
HCM98_RS14520 (HCM98_14545)	2805028..2806497	-	1470	WP_029438358.1	beta-Ala-His dipeptidase	-
HCM98_RS14525 (HCM98_14550)	2806641..2806817	-	177	WP_029438357.1	stage II sporulation protein SB	-
HCM98_RS14530 (HCM98_14555)	2806890..2807018	-	129	WP_029438356.1	hypothetical protein	Antitoxin
HCM98_RS14535 (HCM98_14560)	2807131..2807868	-	738	WP_029438355.1	type II toxin-antitoxin system SpoIISA family toxin	Toxin
HCM98_RS14540 (HCM98_14565)	2808057..2808794	-	738	WP_029438354.1	2,3-diphosphoglycerate-dependent phosphoglycerate mutase	-
HCM98_RS14545 (HCM98_14570)	2808961..2809443	-	483	WP_029438353.1	MarR family winged helix-turn-helix transcriptional regulator	-
HCM98_RS14550 (HCM98_14575)	2809550..2811235	+	1686	WP_033694540.1	alpha-keto acid decarboxylase family protein	-
HCM98_RS14555 (HCM98_14580)	2811283..2811690	-	408	WP_029438351.1	VOC family protein	-
HCM98_RS14560 (HCM98_14585)	2811810..2812520	-	711	WP_029438350.1	class I SAM-dependent methyltransferase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin SpoIISA, type II toxin-antitoxin system (9-243)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 246 a.a.
• Molecular weight: 28389.17 Da
• Isoelectric Point: 8.2638

>T153548 WP_029438355.1 NZ_CP051013:c2807868-2807131 [Bacillus tropicus]
VISNIRIGLFILVIVFLVLVFFYWKNEELYEEKKQRIRKTWYGLFIISVTVYFMIKGIDLTLWKNLLMFTAMVIFVDIAF
ILTPNISEIWGAKFSDIGKTVQSIKRSLIASKARGEIYTTIIQNVNPAVFGTMEWHTEEEYTKSLNAFLDSYGEKIGAKI
VVFEAAKELNTNFRGIRSQFSIMIPLEYIEQLNEQKAVQVENVGIIPAKIVSDVFIVIDGKKNNLQDRDFENVYNLTIHH
SYFSK

Nucleotide

• Length: 738 bp

>T153548 NZ_CP066958:3854088-3854579 [Xanthomonas campestris]
ATGACGGTATCGGCGCCGGAACCGCTGACAGCGCATCACCGGGTCGAACCGTTCGCATCGGGCGTGGAGAGCCTGGATCA
CTGGCTCAAGCGCCGCGCCCTGAAAAATCAGGCAACCGGTGCGTCACGGACCTTCGTTGCCTGCGAGGATGACCGCGTGG
TGGCCTATTACGCCCTGGCGTCGAGTGCGGTCGCCGTGGACGCGACGCCCGGCCGCTTCCGTCGCAACATGCCGGACCCG
ATCCCCGTGGTGGTGCTTGGCAGGCTTGCTGTTGACCAATCCCTGCATGGCAGAGGTTTTGGCCGCGCCCTGGTGCAGGA
TGCTGGCAAGCGCATCCTGCATGCGGCCGACACCATCGGCATTCGCGGGCTGCTCGTGCATGCGCTCTCGTCGGACGCCA
AGGCGTTTTACGAGCGCATCGGCTTCGAACCTTCCCCGCTGGATCCCATGGTGCTGGTCGTCACGCTGGAAGACCTGAAA
GCCAGTCTGTGA

Antitoxin

Protein

• Length: 43 a.a.
• Molecular weight: 5025.42 Da
• Isoelectric Point: 3.9150

>AT153548 WP_029438356.1 NZ_CP051013:c2807018-2806890 [Bacillus tropicus]
VIKDYDNDFFKEDNEDTTDFSLIKGDTLQQVEELEEELKRKS

Nucleotide

• Length: 129 bp

>AT153548 NZ_CP066958:3853801-3854091 [Xanthomonas campestris]
ATGTCCACACCCAACACTACGCCCGGCAAGCGCGAAACCTTGAATCTCCGCATCAAGCCGGAGGAGCGCAGCCTGATCGA
CCGGGCCGCCAAGGCGCGCGGGAAGAACCGCACCGATTTCATGCTGGACGCAGCGCGCTCGGCGGCCGAGGAAGCCTTGC
TGGACCAGACCCTCATCACGGCCAGCCCGGACGCCTACGCCGCCTTTTTGGCACGGCTGGACATGCCGCCGCAGCCGAAC
GCGCGCCTGCGCAAGACGATGCAGACGCCCGCTCCTTGGGAGAAGGCATGA