Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3527251..3527522 Replicon chromosome
Accession NZ_CP051001
Organism Escherichia coli O157:H16 str. 98-3133

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3527289..3527392 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3527251..3527522 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BY40_RS17300 3524408..3525847 + 1440 WP_001352260.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
BY40_RS17305 3525965..3526201 + 237 WP_001295499.1 YebV family protein -
BY40_RS17310 3526306..3526497 + 192 WP_000457842.1 YebW family protein -
BY40_RS17315 3526498..3527154 - 657 WP_000812724.1 protein-serine/threonine phosphatase -
- 3527251..3527522 + 272 - - Antitoxin
- 3527289..3527392 - 104 - - Toxin
BY40_RS17320 3527550..3527891 - 342 WP_000976476.1 YebY family protein -
BY40_RS17325 3527904..3528776 - 873 WP_000879289.1 copper homeostasis membrane protein CopD -
BY40_RS17330 3528780..3529154 - 375 WP_000168747.1 CopC domain-containing protein YobA -
BY40_RS17335 3529293..3529523 + 231 WP_000916763.1 DNA polymerase III subunit theta -
BY40_RS17340 3529625..3530281 + 657 WP_000011658.1 carbon-nitrogen hydrolase family protein YobB -
BY40_RS17345 3530305..3530967 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T153515 NZ_CP051001:c3527392-3527289 [Escherichia coli O157:H16 str. 98-3133]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT153515 NZ_CP051001:3527251-3527522 [Escherichia coli O157:H16 str. 98-3133]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References