Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) hipBA/HipA-couple_hipB
Location 10967..12581 Replicon plasmid unnamed
Accession NZ_CP050991
Organism Chromobacterium violaceum strain FDAARGOS_635

Toxin (Protein)


Gene name hipA Uniprot ID -
Locus tag FOB43_RS00065 Protein ID WP_168226872.1
Coordinates 11232..12581 (+) Length 450 a.a.

Antitoxin (Protein)


Gene name hipB Uniprot ID -
Locus tag FOB43_RS00060 Protein ID WP_080762345.1
Coordinates 10967..11230 (+) Length 88 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FOB43_RS00030 6070..6798 - 729 WP_052262949.1 hypothetical protein -
FOB43_RS00035 6822..6986 - 165 WP_155295399.1 hypothetical protein -
FOB43_RS00040 6983..7465 - 483 WP_155295398.1 phage tail protein -
FOB43_RS00045 7519..7965 - 447 WP_043616556.1 phage tail protein -
FOB43_RS00050 7980..9395 - 1416 WP_043616553.1 phage tail sheath family protein -
FOB43_RS00055 9749..10372 + 624 WP_168226871.1 recombinase family protein -
FOB43_RS00060 10967..11230 + 264 WP_080762345.1 helix-turn-helix domain-containing protein Antitoxin
FOB43_RS00065 11232..12581 + 1350 WP_168226872.1 type II toxin-antitoxin system HipA family toxin Toxin
FOB43_RS00070 12886..14067 - 1182 WP_168226873.1 replication initiator protein A -
FOB43_RS00075 14430..15257 + 828 WP_043616644.1 AAA family ATPase -
FOB43_RS00080 15241..16146 + 906 WP_043616641.1 ParB/RepB/Spo0J family partition protein -
FOB43_RS00085 16170..17120 + 951 WP_168226874.1 replication initiator protein A -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..42965 42965
- flank IS/Tn - - 9749..10372 623


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HipA, N-terminal subdomain 1

(9-110)

Antitoxin

Cro/C1-type helix-turn-helix domain

(18-65)


Sequences

Toxin        


Download         Length: 450 a.a.        Molecular weight: 49841.96 Da        Isoelectric Point: 8.5001

>T153472 WP_168226872.1 NZ_CP050991:11232-12581 [Chromobacterium violaceum]
MGRRKQQQKLHVWMNGLPVGSWETGRAGDRLTYFDDWVAHPQGRPLSLSLPFLPGGMPHQGTAVAAFFDNLLPDSEAIRR
RLAQRHRLAETSPFQLLSALGRDCVGAIQLLPEDETPQDLRTIRGEALDEAGVARLLRQAVAAEPLGLREDEADLRLSIA
GAQEKTALLRHAGRWLLPRNSTPTTHIFKLPLGLVGGMQADMRSSVENEWLCSRLVAGFGLPVAACQIARFEEQKVLVVE
RFDRRLSADGSWILRQPQEDMCQATATPPHLKYQADGGPGIARILDILDGSQARERDRMDFFRAQLVFWLLAATDGHAKN
FSLFHLPGGQYQATPLYDILSAHPIIGNGSGRIAPQKVKLAMAVRRRSNHYLLERIRYGHWLAQARQVGLAPGQAARWID
ELVEQTDGVVQTVAKELPADFPQDVADAIFQGMRRQRDKLAAGKLAGDE

Download         Length: 1350 bp

>T153472 NZ_CP066919:708898-709389 [Xanthomonas campestris pv. campestris]
ATGACGGTATCGGCGCCGGAACCGCTGACAGCGCATCACCGGGTCGAACCGTTCGCATCGGGCGTGGAGAGCCTGGATCA
CTGGCTCAAGCGCCGCGCCCTGAAAAATCAGGCAACCGGTGCGTCACGGACCTTCGTTGCCTGCGAGGATGACCGCGTGG
TGGCCTATTACGCCCTGGCGTCGAGTGCGGTCGCCGTGGACGCGACGCCCGGCCGCTTCCGTCGCAACATGCCGGACCCG
ATCCCCGTGGTGGTGCTTGGGAGGCTTGCTGTTGACCAATCCCTGCATGGCAGAGGTTTTGGCCGCGCCCTGATGCAGGA
TGCTGGCAAGCGCATCCTGCATGCGGCCGACACCATCGGCATTCGCGGGCTGCTCGTGCATGCGCTCTCGGCGGACGCCA
AGGCGTTTTACGAGCGCATCGGCTTCGAACCTTCCCCGCTGGATCCCATGGTGCTGGTCGTCACGCTGGAAGACCTGAAA
GCCAGTCTGTGA

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 9343.64 Da        Isoelectric Point: 8.5767

>AT153472 WP_080762345.1 NZ_CP050991:10967-11230 [Chromobacterium violaceum]
MHYPVRTLEQLRPLLLGLRKAAGLTQTQLAARLGVSQQSYARLEANPAAASVERLYRALRALDAELALSSPGSPPPPSAA
DAHGEEW

Download         Length: 264 bp

>AT153472 NZ_CP066919:708611-708901 [Xanthomonas campestris pv. campestris]
ATGTCCACACCCAACACTACGCCTGGCAAGCGCGAAACCTTGAATCTCCGCATCAAGCCGGAGGAGCGCAGCCTGATCGA
CCGGGCCGCCAAGGCGCGCGGGAAGAACCGCACCGATTTCATGCTGGACGCAGCGCGCTCGGCGGCCGAGGAAGCCTTGC
TGGACCAGACCCTCATCACGGCCAGCCCGGACGCCTACGCCGCCTTTTTGGCACGGCTGGACATGCCGCCGCAGCCGAAC
GCGCGCCTGCGCAAGACGATGCAGACGCCCGCTCCTTGGGAGAAGGCATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References