Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /BrnT(toxin)
Location 696509..696956 Replicon plasmid unnamed
Accession NZ_CP050953
Organism Rhodococcus sp. DMU1

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag HFP48_RS31160 Protein ID WP_168581187.1
Coordinates 696509..696730 (+) Length 74 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag HFP48_RS31165 Protein ID WP_168581112.1
Coordinates 696720..696956 (+) Length 79 a.a.

Genomic Context

HFP48_RS31140HFP48_RS31145HFP48_RS31160HFP48_RS31165HFP48_RS31170HFP48_RS31195HFP48_RS31150HFP48_RS31155HFP48_RS31175HFP48_RS31180HFP48_RS31185HFP48_RS31190
Location: 693706..694950 (1245 bp)
Type: Others
Protein ID: Protein_621
Location: 695274..695417 (144 bp)
Type: Others
Protein ID: WP_168581109.1
Location: 696509..696730 (222 bp)
Type: Toxin
Protein ID: WP_168581187.1
Location: 696720..696956 (237 bp)
Type: Antitoxin
Protein ID: WP_168581112.1
Location: 697054..697342 (289 bp)
Type: Others
Protein ID: Protein_627
Location: 701036..701302 (267 bp)
Type: Others
Protein ID: WP_168581189.1
Location: 695449..695799 (351 bp)
Type: Others
Protein ID: WP_168581110.1
Location: 695802..696260 (459 bp)
Type: Others
Protein ID: WP_168581111.1
Location: 697737..699146 (1410 bp)
Type: Others
Protein ID: WP_168581188.1
Location: 699191..699372 (182 bp)
Type: Others
Protein ID: Protein_629
Location: 699819..700124 (306 bp)
Type: Others
Protein ID: WP_168580683.1
Location: 700138..700842 (705 bp)
Type: Others
Protein ID: WP_168581113.1
ToxinAntitoxinOther genes
Loading, please wait
Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
HFP48_RS31140693706..694950+1245Protein_621AAA family ATPase-
HFP48_RS31145695274..695417+144WP_168581109.1hypothetical protein-
HFP48_RS31150695449..695799-351WP_168581110.1hypothetical protein-
HFP48_RS31155695802..696260-459WP_168581111.1prevent-host-death protein-
HFP48_RS31160696509..696730+222WP_168581187.1BrnT family toxinToxin
HFP48_RS31165696720..696956+237WP_168581112.1CopG family transcriptional regulatorAntitoxin
HFP48_RS31170697054..697342+289Protein_627hypothetical protein-
HFP48_RS31175697737..699146-1410WP_168581188.1plasmid pRiA4b ORF-3 family protein-
HFP48_RS31180699191..699372-182Protein_629hypothetical protein-
HFP48_RS31185699819..700124-306WP_168580683.1alpha/beta hydrolase-
HFP48_RS31190700138..700842-705WP_168581113.1DUF899 family protein-
HFP48_RS31195701036..701302+267WP_168581189.1hypothetical protein-

Associated MGEs

Loading, please wait
MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideNon-Mobilizable plasmid--1..716018716018
-flankIS/Tn--701387..702340953


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease toxin, BrnT, of type II toxin-antitoxin system

(2-66)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 74 a.a.        Molecular weight: 8375.57 Da        Isoelectric Point: 10.2993

>T153469 WP_168581187.1 NZ_CP050953:696509-696730 [Rhodococcus sp. DMU1]
MAKHGIDFLSAQALWRDPHRLEVPAKTTDEPRWLVIGVIDGKWWSAVVTYRAGRTRIISVRRSRDGEVAPYES

Download         Length: 222 bp

>T153469 NZ_CP066916:53208-53357 [Klebsiella pneumoniae]
ATGACGAAATATGCCCTTATCGGGTTGCTCGCCGTGTGTGCCACGGTATTGTGTTTTTCACTGATATTCAGGGAACGGTT
ATGTGAACTGAATATTCACAGGGGAAATACAGTGGTGCAGGTAACTCTGGCCTACGAAGCACGGAAGTAA

Antitoxin


Download         Length: 79 a.a.        Molecular weight: 9011.04 Da        Isoelectric Point: 4.6702

>AT153469 WP_168581112.1 NZ_CP050953:696720-696956 [Rhodococcus sp. DMU1]
MRADEFDERFDAGEDVTFALDTARARRPGEEQRRVNVDFPAWMIAELDREATRLGVTRQSLIKVWIAERLERNGSTAT

Download         Length: 237 bp

>AT153469 NZ_CP066916:c53163-53104 [Klebsiella pneumoniae]
TAAGTACTTCATGCAGACCTCACGAGTTAATGGATTAACGAGTGGGGTCTTCGCATTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

Loading, please wait
Source
ID
Structure
No matching records found

Antitoxin

Loading, please wait
Source
ID
Structure
No matching records found

References