Detailed information of TA system TA153451

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): cptAB/-
• Location: 458885..459526
• Replicon: chromosome
• Accession: NZ_CP050916
• Organism: Acinetobacter baumannii strain DT-Ab003

Toxin (Protein)

• Gene name: cptA
• Uniprot ID: -
• Locus tag: HFD83_RS02250
• Protein ID: WP_000607077.1
• Coordinates: 459137..459526 (+)
• Length: 130 a.a.

Antitoxin (Protein)

• Gene name: cptB
• Uniprot ID: -
• Locus tag: HFD83_RS02245
• Protein ID: WP_011860336.1
• Coordinates: 458885..459130 (+)
• Length: 82 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
HFD83_RS02225	454389..455396	+	1008	WP_000198631.1	DNA-directed RNA polymerase subunit alpha	-
HFD83_RS02230	455415..455792	+	378	WP_001216380.1	50S ribosomal protein L17	-
HFD83_RS02235	455974..457464	+	1491	WP_000415125.1	NAD(P)/FAD-dependent oxidoreductase	-
HFD83_RS02240	457513..458685	-	1173	WP_001190542.1	acyl-CoA dehydrogenase family protein	-
HFD83_RS02245	458885..459130	+	246	WP_011860336.1	succinate dehydrogenase assembly factor 2	Antitoxin
HFD83_RS02250	459137..459526	+	390	WP_000607077.1	membrane protein	Toxin
HFD83_RS02255	460296..461381	+	1086	WP_000049106.1	hypothetical protein	-
HFD83_RS02260	461459..462025	+	567	WP_000651538.1	rhombosortase	-
HFD83_RS02265	462213..464408	+	2196	WP_038350236.1	TRAP transporter large permease subunit	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

• Flavinator of succinate dehydrogenase (6-78)

Sequences

Toxin

Protein

• Length: 130 a.a.
• Molecular weight: 15552.88 Da
• Isoelectric Point: 10.4313

>T153451 WP_000607077.1 NZ_CP050916:459137-459526 [Acinetobacter baumannii]
MINHLNFKLKYSRFSIIFQFFIGLSLAVLFYQLMPLLWWLVVISLLFISFIFFLKRPQLAQIAYLDKKLWSLAYKSQNTV
SRVKILKIIDCQIFIVIYFEGHKTLTSIIWFDQMSLAEWKKLKTLEKLY

Nucleotide

• Length: 390 bp

>T153451 NZ_CP066911:271084-271371 [Klebsiella pneumoniae]
ATGGCGTATTTTCTGGATTTTGACGAGCGGGCACTAAAGGAATGGCGAAAGCTGGGCTCGACGGTACGTGAACAGTTGAA
AAAGAAGCTGGTTGAAGTACTTGAGTCACCCCGGATTGAAGCAAACAAGCTCCGTGGTATGCCTGATTGTTACAAGATTA
AGCTCCGGTCTTCAGGCTATCGCCTTGTATACCAGGTTATAGACGAGAAAGTTGTCGTTTTCGTGATTTCTGTTGGGAAA
AGAGAACGCTCGGAAGTATATAGCGAGGCGGTCAAACGCATTCTCTGA

Antitoxin

Protein

• Length: 82 a.a.
• Molecular weight: 9842.27 Da
• Isoelectric Point: 4.9001

>AT153451 WP_011860336.1 NZ_CP050916:458885-459130 [Acinetobacter baumannii]
MTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIYKLKHYVH
G

Nucleotide

• Length: 246 bp

>AT153451 NZ_CP066911:270845-271084 [Klebsiella pneumoniae]
ATGGGTAGCATTAACCTACGTATTGACGATGAACTTAAAGCGCGTTCTTACGCCGCGCTTGAAAAAATGGGCGTAACTCC
TTCTGAAGCGCTTCGTCTCATGCTCGAGTATATCGCTGACAATGAACGCTTGCCGTTCAAACAGACACTCCTGAGTGATG
AAGATGCTGAACTTGTGGAGATAGTGAAAGAACGACTTCGTAATCCTAAGCCAGTACGTGTGACGCTGGATGAACTCTGA