Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/-
Location 458886..459527 Replicon chromosome
Accession NZ_CP050904
Organism Acinetobacter baumannii strain DT-Ab057

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag HFD79_RS02250 Protein ID WP_000607077.1
Coordinates 459138..459527 (+) Length 130 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag HFD79_RS02245 Protein ID WP_011860336.1
Coordinates 458886..459131 (+) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HFD79_RS02225 454390..455397 + 1008 WP_000198631.1 DNA-directed RNA polymerase subunit alpha -
HFD79_RS02230 455416..455793 + 378 WP_001216380.1 50S ribosomal protein L17 -
HFD79_RS02235 455975..457465 + 1491 WP_000415125.1 NAD(P)/FAD-dependent oxidoreductase -
HFD79_RS02240 457514..458686 - 1173 WP_001190542.1 acyl-CoA dehydrogenase family protein -
HFD79_RS02245 458886..459131 + 246 WP_011860336.1 succinate dehydrogenase assembly factor 2 Antitoxin
HFD79_RS02250 459138..459527 + 390 WP_000607077.1 membrane protein Toxin
HFD79_RS02255 460297..461382 + 1086 WP_000049106.1 hypothetical protein -
HFD79_RS02260 461460..462026 + 567 WP_168161265.1 rhombosortase -
HFD79_RS02265 462214..464409 + 2196 WP_038350236.1 TRAP transporter large permease subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Flavinator of succinate dehydrogenase

(6-78)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 15552.88 Da        Isoelectric Point: 10.4313

>T153437 WP_000607077.1 NZ_CP050904:459138-459527 [Acinetobacter baumannii]
MINHLNFKLKYSRFSIIFQFFIGLSLAVLFYQLMPLLWWLVVISLLFISFIFFLKRPQLAQIAYLDKKLWSLAYKSQNTV
SRVKILKIIDCQIFIVIYFEGHKTLTSIIWFDQMSLAEWKKLKTLEKLY

Download         Length: 390 bp

>T153437 NZ_CP066910:327662-328030 [Klebsiella pneumoniae]
ATGACGCTGCAGATTATCTCAGCGGAAGAGATAATACAGTTTCACGACAGGCTGCTCCGCGTCACGCCTGGCGTTGCCGG
TATGCCCGATCCAGGGCGTGCCGAAGCGATAATGTATAGGGTGCTAAACAAAATTGAATATGAAGGTGTGACAGACGTGT
GGCGACTCGCTGCGATGCATCTGCTGGCGATTTCTCGCGGTCATATATTTAATGATGGTAATAAGCGTACGGCACTGTTT
ATCACTCTGCTTTTTTTAAAGCGAAATGGAATTATATTGCCGGCGAATCCAGACTTCGTCGGCATGACCGTCGAGGCGGC
AGCAGGGCAACTTACCCTGGAACAGATTGTCGCGCGCTTGCGCGGATGA

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 9842.27 Da        Isoelectric Point: 4.9001

>AT153437 WP_011860336.1 NZ_CP050904:458886-459131 [Acinetobacter baumannii]
MTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIYKLKHYVH
G

Download         Length: 246 bp

>AT153437 NZ_CP066910:327444-327665 [Klebsiella pneumoniae]
ATGAGAACGGTTAACTATAGCGAAGCCCGGCAAAATCTGGCCGATGTGCTGGAAAGCGCAGTGACAGGTGTACCTGTGAC
CATTACCCGTCGTGGGCATAAATCTGCAGTCATCATTAGTGCAGAAGAGTTTGAACGCTACCAGACGGCCAGAATGGATG
ATGAGTTCGCGGCTATCATGGCGGTTCATGGTGATGAGATCAGGGAGCTTGCGGATAAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References