Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 4728949..4729180 | Replicon | chromosome |
| Accession | NZ_CP050865 | ||
| Organism | Escherichia coli strain 8-3-Ti3 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 4729076..4729179 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 4728949..4729180 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| HFC66_RS23855 | 4725502..4726164 | - | 663 | WP_000944256.1 | exodeoxyribonuclease X | - |
| HFC66_RS23860 | 4726188..4726844 | - | 657 | WP_032359391.1 | carbon-nitrogen hydrolase family protein | - |
| HFC66_RS23865 | 4726946..4727176 | - | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
| HFC66_RS23870 | 4727315..4727689 | + | 375 | WP_066018956.1 | CopC domain-containing protein YobA | - |
| HFC66_RS23875 | 4727693..4728565 | + | 873 | WP_000879298.1 | copper homeostasis membrane protein CopD | - |
| HFC66_RS23880 | 4728578..4728919 | + | 342 | WP_073849646.1 | YebY family protein | - |
| - | 4728949..4729180 | - | 232 | - | - | Antitoxin |
| - | 4729076..4729179 | + | 104 | - | - | Toxin |
| HFC66_RS23885 | 4729301..4730377 | - | 1077 | WP_052993702.1 | phage integrase Arm DNA-binding domain-containing protein | - |
| HFC66_RS23890 | 4730343..4730624 | - | 282 | WP_005127484.1 | excisionase | - |
| HFC66_RS23895 | 4730731..4730919 | - | 189 | WP_000276808.1 | DUF1187 family protein | - |
| - | 4730735..4730913 | + | 179 | NuclAT_2 | - | - |
| - | 4730735..4730913 | + | 179 | NuclAT_2 | - | - |
| - | 4730735..4730913 | + | 179 | NuclAT_2 | - | - |
| - | 4730735..4730913 | + | 179 | NuclAT_2 | - | - |
| HFC66_RS23900 | 4730970..4731575 | - | 606 | Protein_4647 | hypothetical protein | - |
| HFC66_RS23905 | 4731593..4732290 | - | 698 | Protein_4648 | IS1 family transposase | - |
| HFC66_RS23910 | 4732333..4732539 | + | 207 | Protein_4649 | hypothetical protein | - |
| HFC66_RS23920 | 4733134..4733346 | + | 213 | WP_000935258.1 | type I toxin-antitoxin system Hok family toxin | - |
| HFC66_RS23925 | 4733514..4733792 | + | 279 | WP_000929754.1 | hypothetical protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | flank | IS/Tn | - | - | 4731593..4732096 | 503 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T153420 NZ_CP050865:4729076-4729179 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
Antitoxin
Download Length: 232 bp
>AT153420 NZ_CP050865:c4729180-4728949 [Escherichia coli]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTT
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTT
