Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 1561670..1561901 | Replicon | chromosome |
| Accession | NZ_CP050862 | ||
| Organism | Escherichia coli strain 8-3-DC15 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 1561797..1561900 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 1561670..1561901 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| HFC67_RS08035 | 1558223..1558885 | - | 663 | WP_000944256.1 | exodeoxyribonuclease X | - |
| HFC67_RS08040 | 1558909..1559565 | - | 657 | WP_032359391.1 | carbon-nitrogen hydrolase family protein | - |
| HFC67_RS08045 | 1559667..1559897 | - | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
| HFC67_RS08050 | 1560036..1560410 | + | 375 | WP_066018956.1 | CopC domain-containing protein YobA | - |
| HFC67_RS08055 | 1560414..1561286 | + | 873 | WP_000879298.1 | copper homeostasis membrane protein CopD | - |
| HFC67_RS08060 | 1561299..1561640 | + | 342 | WP_073849646.1 | YebY family protein | - |
| - | 1561670..1561901 | - | 232 | - | - | Antitoxin |
| - | 1561797..1561900 | + | 104 | - | - | Toxin |
| HFC67_RS08065 | 1562022..1563098 | - | 1077 | WP_052993702.1 | phage integrase Arm DNA-binding domain-containing protein | - |
| HFC67_RS08070 | 1563064..1563345 | - | 282 | WP_005127484.1 | excisionase | - |
| HFC67_RS08075 | 1563452..1563640 | - | 189 | WP_000276806.1 | DUF1187 family protein | - |
| - | 1563456..1563634 | + | 179 | NuclAT_1 | - | - |
| - | 1563456..1563634 | + | 179 | NuclAT_1 | - | - |
| - | 1563456..1563634 | + | 179 | NuclAT_1 | - | - |
| - | 1563456..1563634 | + | 179 | NuclAT_1 | - | - |
| HFC67_RS08080 | 1563680..1564285 | - | 606 | Protein_1572 | hypothetical protein | - |
| HFC67_RS08085 | 1564303..1565000 | - | 698 | Protein_1573 | IS1 family transposase | - |
| HFC67_RS08090 | 1565043..1565249 | + | 207 | Protein_1574 | hypothetical protein | - |
| HFC67_RS08100 | 1565844..1566056 | + | 213 | WP_000935258.1 | type I toxin-antitoxin system Hok family toxin | - |
| HFC67_RS08105 | 1566224..1566502 | + | 279 | WP_000929754.1 | hypothetical protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | ipaH9.8 / ipaH9.8 | 1484914..1616724 | 131810 | |
| - | flank | IS/Tn | - | - | 1564303..1564806 | 503 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T153388 NZ_CP050862:1561797-1561900 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
Antitoxin
Download Length: 232 bp
>AT153388 NZ_CP050862:c1561901-1561670 [Escherichia coli]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTT
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTT
