Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2679463..2679608 Replicon chromosome
Accession NZ_CP050858
Organism Klebsiella pneumoniae strain SCH6109

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2679499..2679601 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2679463..2679608 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HC233_RS13070 2674592..2676652 + 2061 WP_004151449.1 oligopeptidase B -
HC233_RS13075 2676656..2677315 - 660 WP_002911407.1 exodeoxyribonuclease X -
HC233_RS13080 2677394..2677624 - 231 WP_002911406.1 DNA polymerase III subunit theta -
HC233_RS13085 2677737..2678111 + 375 WP_004151448.1 CopC domain-containing protein YobA -
HC233_RS13090 2678115..2678985 + 871 Protein_2486 copper homeostasis membrane protein CopD -
HC233_RS13095 2679002..2679340 + 339 WP_002911404.1 YebY family protein -
- 2679463..2679608 - 146 - - Antitoxin
- 2679499..2679601 + 103 - - Toxin
HC233_RS13100 2679976..2680119 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
HC233_RS13105 2680224..2681192 - 969 WP_004151446.1 VirK/YbjX family protein -
HC233_RS13110 2681349..2682002 + 654 WP_020802220.1 protein-serine/threonine phosphatase -
HC233_RS13115 2681999..2682190 - 192 WP_002911395.1 YebW family protein -
HC233_RS13120 2682288..2682527 - 240 WP_002911393.1 YebV family protein -
HC233_RS13125 2682643..2684076 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T153370 NZ_CP050858:2679499-2679601 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT153370 NZ_CP050858:c2679608-2679463 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References