Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 4822121..4822648 Replicon chromosome
Accession NZ_CP050854
Organism Brenneria izadpanahii strain Iran 50

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag HC231_RS21560 Protein ID WP_208228710.1
Coordinates 4822373..4822648 (+) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag HC231_RS21555 Protein ID WP_208228709.1
Coordinates 4822121..4822369 (+) Length 83 a.a.

Genomic Context

HC231_RS21520HC231_RS21525HC231_RS21530HC231_RS21535HC231_RS21540HC231_RS21545HC231_RS21550HC231_RS21555HC231_RS21560HC231_RS21565HC231_RS24075HC231_RS21570HC231_RS21575HC231_RS21580
Location: 4817805..4818170 (366 bp)
Type: Others
Protein ID: WP_208228704.1
Location: 4818213..4818620 (408 bp)
Type: Others
Protein ID: WP_116162565.1
Location: 4818948..4819769 (822 bp)
Type: Others
Protein ID: WP_208228705.1
Location: 4819822..4820295 (474 bp)
Type: Others
Protein ID: WP_208228706.1
Location: 4820335..4820670 (336 bp)
Type: Others
Protein ID: WP_208228707.1
Location: 4820740..4821060 (321 bp)
Type: Others
Protein ID: WP_130640181.1
Location: 4821178..4822011 (834 bp)
Type: Others
Protein ID: WP_208228708.1
Location: 4822121..4822369 (249 bp)
Type: Antitoxin
Protein ID: WP_208228709.1
Location: 4822373..4822648 (276 bp)
Type: Toxin
Protein ID: WP_208228710.1
Location: 4822776..4823693 (918 bp)
Type: Others
Protein ID: WP_208228711.1
Location: 4823926..4824084 (159 bp)
Type: Others
Protein ID: WP_246494612.1
Location: 4824077..4824721 (645 bp)
Type: Others
Protein ID: WP_246494614.1
Location: 4825330..4825710 (381 bp)
Type: Others
Protein ID: WP_208231466.1
Location: 4825895..4826268 (374 bp)
Type: Others
Protein ID: Protein_4250
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
HC231_RS21520 (HC231_21530)4817805..4818170+366WP_208228704.1hypothetical protein-
HC231_RS21525 (HC231_21535)4818213..4818620+408WP_116162565.1hypothetical protein-
HC231_RS21530 (HC231_21540)4818948..4819769+822WP_208228705.1DUF932 domain-containing protein-
HC231_RS21535 (HC231_21545)4819822..4820295+474WP_208228706.1DNA repair protein RadC-
HC231_RS21540 (HC231_21550)4820335..4820670+336WP_208228707.1type IV toxin-antitoxin system YeeU family antitoxin-
HC231_RS21545 (HC231_21555)4820740..4821060+321WP_130640181.1TA system toxin CbtA family protein-
HC231_RS21550 (HC231_21560)4821178..4822011+834WP_208228708.1DUF4942 domain-containing protein-
HC231_RS21555 (HC231_21565)4822121..4822369+249WP_208228709.1ribbon-helix-helix domain-containing proteinAntitoxin
HC231_RS21560 (HC231_21570)4822373..4822648+276WP_208228710.1type II toxin-antitoxin system RelE/ParE family toxinToxin
HC231_RS21565 (HC231_21575)4822776..4823693+918WP_208228711.1hypothetical protein-
HC231_RS240754823926..4824084+159WP_246494612.1helix-turn-helix domain-containing protein-
HC231_RS21570 (HC231_21580)4824077..4824721+645WP_246494614.1transcriptional regulator-
HC231_RS21575 (HC231_21585)4825330..4825710-381WP_208231466.1DUF1493 family protein-
HC231_RS21580 (HC231_21590)4825895..4826268-374Protein_4250transposase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideGenomic island--4812703..483826125558
-flankIS/Tn--4826029..4826268239


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-90)

Antitoxin

Ribbon-helix-helix protein, CopG

(9-43)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10989.22 Da        Isoelectric Point: 5.1487

>T153348 WP_208228710.1 NZ_CP050854:4822373-4822648 [Brenneria izadpanahii]
MEIRWTQKAQDDLERIYGFASQYSRQHADEVLDRLIIGTTGLADHPRIGVSQARYEPREVRKILFDDYEVHYEIQHDTIY
IVDLWHTREDR

Download         Length: 276 bp

>T153348 NZ_CP066853:c2638383-2637814 [Rhodococcus biphenylivorans]
ATGAGGCGTCTGGATCTGATCGTCGGTCCCAACGGTTCCGGCAAGTCGACGTTCGTCGAGTTGTCCCTCGCTCCCCTGCT
GCCGCGCAGCGTGTTCGTCAATGCGGATGTGATCGCGCGGCAGCGCTGGCCCGACCGGGCGGAGGAGATGTCGTACGAGG
CGGCGCAGCTCGCCGCGGCGGCGCGGGACCGGTTGCTGCGGCAGGGCCGGTCGTTCATTGCGGAGACGGTGTTCTCGCAT
CCGTCGAAGCTGGAGTTGATCGACCGCGCGCACGAGGTGGGGTTCACGGTGGTGCTGCACGTGATGCTGGTGCCCGAGGC
GATGTCGGTGCTGCGTGTACAGCACCGGGTGGCCTCCGGTGGGCATGCGGTGCCCGAGGACAAGATCCGGGCGCGTTATC
GGCGGTTGTGGCCGCTGGTGACCGAAGCGATCGGCCGCGCCGATCAGGCGTCGGTGTACGACACGGCGTCCGGGACCCCG
GTGGTGGTGGCGCGGTTCGCCGGCGGGGTGCCGGTGGGTGCGGTGCGCTGGCCGGGATGGGCGCCGGCGGCGCTCACCGG
GCTCGGCTGA

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 8983.32 Da        Isoelectric Point: 7.2045

>AT153348 WP_208228709.1 NZ_CP050854:4822121-4822369 [Brenneria izadpanahii]
MGQSAKQTISAQIPAELAAAVESLAIELDRSKSWVIKEALTAMIEERERRHQQILKGLADVDAGRVVSHADVIDFANKLK
KS

Download         Length: 249 bp

>AT153348 NZ_CP066853:c2638766-2638380 [Rhodococcus biphenylivorans]
ATGACGTCATCCACCGACAAGGTCACCCGCTTCGACGCCGAACTCGTCGACAGCGCCATCGCCGAGGGTGGCCGCCAGAA
CCGCACCGGACGCCAGCAACTCGAGTACTGGGCCCGCATCGGCCGCGCGATGACCGCCCACGAGACCGCCTCCCTGCACC
GGGTGCACGAGGCGCTGGCCGGGACACGGGAGCTGAGCGAGCTCACCGCCGCCGAGGGACGGCTGTTCGACGCGGAGATC
GATGCGCTCCTGGCGGACGGGCTGGCCCGCACCGACTACGCCGAGGTTCTCGCCGCGCGTGGGGTCAGCACGGTGGTGCT
CGACGACGAAGGCCGGCTGGTCGAGCAGCGTCCCGACGGTAGTCGCCGGGTGCTCGACGACGCATGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
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Antitoxin

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Source
ID
Structure
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References