Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 4305590..4306115 Replicon chromosome
Accession NZ_CP050854
Organism Brenneria izadpanahii strain Iran 50

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag HC231_RS19215 Protein ID WP_208228307.1
Coordinates 4305831..4306115 (+) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag HC231_RS19210 Protein ID WP_208228306.1
Coordinates 4305590..4305841 (+) Length 84 a.a.

Genomic Context

HC231_RS19180HC231_RS19185HC231_RS19190HC231_RS19195HC231_RS19200HC231_RS19205HC231_RS19210HC231_RS19215HC231_RS19220HC231_RS19230HC231_RS19170HC231_RS19175HC231_RS19225
Location: 4302339..4303019 (681 bp)
Type: Others
Protein ID: WP_208228302.1
Location: 4303100..4303483 (384 bp)
Type: Others
Protein ID: WP_208228303.1
Location: 4303719..4304267 (549 bp)
Type: Others
Protein ID: WP_208228304.1
Location: 4304270..4304725 (456 bp)
Type: Others
Protein ID: WP_208228305.1
Location: 4304889..4305105 (217 bp)
Type: Others
Protein ID: Protein_3779
Location: 4305100..4305329 (230 bp)
Type: Others
Protein ID: Protein_3780
Location: 4305590..4305841 (252 bp)
Type: Antitoxin
Protein ID: WP_208228306.1
Location: 4305831..4306115 (285 bp)
Type: Toxin
Protein ID: WP_208228307.1
Location: 4306556..4306726 (171 bp)
Type: Others
Protein ID: Protein_3783
Location: 4308436..4310391 (1956 bp)
Type: Others
Protein ID: WP_208228310.1
Location: 4300937..4301416 (480 bp)
Type: Others
Protein ID: WP_208228300.1
Location: 4301407..4301679 (273 bp)
Type: Others
Protein ID: WP_208228301.1
Location: 4306760..4308025 (1266 bp)
Type: Others
Protein ID: WP_208228309.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
HC231_RS19170 (HC231_19175)4300937..4301416-480WP_208228300.1GNAT family N-acetyltransferase-
HC231_RS19175 (HC231_19180)4301407..4301679-273WP_208228301.1DUF1778 domain-containing protein-
HC231_RS19180 (HC231_19185)4302339..4303019+681WP_208228302.1hypothetical protein-
HC231_RS19185 (HC231_19190)4303100..4303483+384WP_208228303.1hypothetical protein-
HC231_RS19190 (HC231_19195)4303719..4304267+549WP_208228304.1hypothetical protein-
HC231_RS19195 (HC231_19200)4304270..4304725+456WP_208228305.1hypothetical protein-
HC231_RS19200 (HC231_19205)4304889..4305105+217Protein_3779nuclease-
HC231_RS19205 (HC231_19210)4305100..4305329+230Protein_3780winged helix-turn-helix domain-containing protein-
HC231_RS19210 (HC231_19215)4305590..4305841+252WP_208228306.1type II toxin-antitoxin system Phd/YefM family antitoxinAntitoxin
HC231_RS19215 (HC231_19220)4305831..4306115+285WP_208228307.1type II toxin-antitoxin system RelE/ParE family toxinToxin
HC231_RS19220 (HC231_19225)4306556..4306726+171Protein_3783integrase-
HC231_RS19225 (HC231_19230)4306760..4308025-1266WP_208228309.1alpha-hydroxy-acid oxidizing protein-
HC231_RS19230 (HC231_19235)4308436..4310391+1956WP_208228310.1transporter substrate-binding domain-containing protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-83)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 11010.96 Da        Isoelectric Point: 10.1716

>T153344 WP_208228307.1 NZ_CP050854:4305831-4306115 [Brenneria izadpanahii]
MSYKLEFEEHALKEFKKLGTPVREQFTKKLKEVLQNPHVPANRLHGMADCYKIKLRSAGYRLVYQVIEHEIVVLVLAVGK
RERSEVYKAAKDRL

Download         Length: 285 bp

>T153344 NZ_CP066851:c4564666-4564355 [Salmonella enterica subsp. enterica serovar Heidelberg]
ATGCAATTTATAGAAACGGAACTCTTTACTGAAGATGTTAAAAAACTGCTCGATGAGGATGAATACCATAAGCTTCAGGT
TTTTATGGCTCAGCATCCAGATTGTGGTGATGTCATTCAGGAAACGGGCGGCCTGAGAAAAATGCGCTGGGGAGCGCGAG
GCAAAGGAAAGCGTAGTGGCGTGCGAATTATCTATTTTCACCGTAGTCAACGGTATGAGATTCGCTTGCTTCTGATTTAT
CAAAAAGGCATTAAAGATGATCTCACGCCGCAGGAAAAAGCGGTGCTTCGTATGCTGAATGAGAGGTGGTAG

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9107.41 Da        Isoelectric Point: 5.0807

>AT153344 WP_208228306.1 NZ_CP050854:4305590-4305841 [Brenneria izadpanahii]
MSVQPILANAVVSISDFKKSPNAALKEANGEPVAVLTNGRISGYYVSPETWEALADYQEDIELAKIARSRMKGKRVKVDL
DEL

Download         Length: 252 bp

>AT153344 NZ_CP066851:c4564354-4564064 [Salmonella enterica subsp. enterica serovar Heidelberg]
ATGGATAAAGTGTTATTTGAGCGATTAACTCAAAGTATGTCTCAAATGAATGAAATCATTGAAGGGACCCGTGAGCCTTC
TCGTACCTTTCATATTGATGCAATGAAGATTAAAGAAATACGGCAGGCATCTGGGTTGTCGCAATCTAAGTTTGCAGAAC
TGATTTCGGTCAACGTGGATACGCTGCGCAACTGGGAGCAAGGAAGACGTTCACCGACAGGGCCAGCCAAAGCGTTACTT
CGCGCCATTGCCAACGACCCGAGAAACGTTATACAAGCATTGCGTTATTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References