Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-MqsA
Location 948597..949311 Replicon chromosome
Accession NZ_CP050854
Organism Brenneria izadpanahii strain Iran 50

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag HC231_RS04160 Protein ID WP_208229857.1
Coordinates 948597..948992 (+) Length 132 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag HC231_RS04165 Protein ID WP_208229858.1
Coordinates 948982..949311 (+) Length 110 a.a.

Genomic Context

HC231_RS04155HC231_RS04160HC231_RS04165HC231_RS04170HC231_RS04175HC231_RS04180HC231_RS04185HC231_RS04145HC231_RS04150
Location: 947801..948493 (693 bp)
Type: Others
Protein ID: WP_208229856.1
Location: 948597..948992 (396 bp)
Type: Toxin
Protein ID: WP_208229857.1
Location: 948982..949311 (330 bp)
Type: Antitoxin
Protein ID: WP_208229858.1
Location: 949727..950554 (828 bp)
Type: Others
Protein ID: WP_208229859.1
Location: 950751..952319 (1569 bp)
Type: Others
Protein ID: WP_208229860.1
Location: 952331..952681 (351 bp)
Type: Others
Protein ID: WP_208229861.1
Location: 952694..954082 (1389 bp)
Type: Others
Protein ID: WP_208229862.1
Location: 943828..945375 (1548 bp)
Type: Others
Protein ID: WP_208229854.1
Location: 945723..947279 (1557 bp)
Type: Others
Protein ID: WP_208229855.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
HC231_RS04145 (HC231_04145)943828..945375-1548WP_208229854.1hypothetical protein-
HC231_RS04150 (HC231_04150)945723..947279-1557WP_208229855.1methyl-accepting chemotaxis protein-
HC231_RS04155 (HC231_04155)947801..948493+693WP_208229856.1glutamine amidotransferase-
HC231_RS04160 (HC231_04160)948597..948992+396WP_208229857.1type II toxin-antitoxin system RelE/ParE family toxinToxin
HC231_RS04165 (HC231_04165)948982..949311+330WP_208229858.1helix-turn-helix domain-containing proteinAntitoxin
HC231_RS04170 (HC231_04170)949727..950554+828WP_208229859.1nitrogenase iron protein-
HC231_RS04175 (HC231_04175)950751..952319+1569WP_208229860.1nitrogenase iron-iron protein, alpha chain-
HC231_RS04180 (HC231_04180)952331..952681+351WP_208229861.1Fe-only nitrogenase subunit delta-
HC231_RS04185 (HC231_04185)952694..954082+1389WP_208229862.1Fe-only nitrogenase subunit beta-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-2

(5-126)

Antitoxin

Cro/C1-type helix-turn-helix domain

(53-94)


Sequences

Toxin        


Download         Length: 132 a.a.        Molecular weight: 14802.12 Da        Isoelectric Point: 9.1075

>T153340 WP_208229857.1 NZ_CP050854:948597-948992 [Brenneria izadpanahii]
MDLAIYTTKLFDRKMKKEDVTDVDLCQAAADVMNGDFEADLGGGVLKKRLALQSGKSGGARSIIFFKKGSNVFFFDGWRK
NQITRKGAKEIEEDVLKTYKDFAEVFLQYDAAMITRLKKVKQLREVNCDGC

Download         Length: 396 bp

>T153340 NZ_CP066851:c2539805-2539521 [Salmonella enterica subsp. enterica serovar Heidelberg]
ATGACTTATAAGCTGGCATTTAACGAATCAGCACTAAAAGAGTGGAAAAAAATGGGTCATACCATACAGGAACAGTTTAA
AAAAAAGTTACGGGAACGTCTTGAAAACCCTCGGGTTCCGGCTTCGCAATTACATGGAAGAAAGGATCAGTACAAAATTA
AGCTGCGTGGTGCAGGATACAGACTGGTGTACAGCGTCGAAGATGAAATTATCACGGTAACTGTCATTGGTGTTGGAAAG
CGTGAAAATGATGCCGTCTACAAAATGACACGACACAGAAGCTAA

Antitoxin


Download         Length: 110 a.a.        Molecular weight: 12223.13 Da        Isoelectric Point: 9.6910

>AT153340 WP_208229858.1 NZ_CP050854:948982-949311 [Brenneria izadpanahii]
MAANLKELQALAQELHEHGAMPDETMSRINARVKSRELRERIAKVHIMTGTQIKSMRERYGMSQSTLAYTLGMSVESVSK
WERGEIQPSGPALRILNTIDAKGPEVFVL

Download         Length: 330 bp

>AT153340 NZ_CP066851:c2540043-2539795 [Salmonella enterica subsp. enterica serovar Heidelberg]
ATGGCATTTCAAATTTTAACGACTACTGCAGCAAGCATTACAGAACTGAAACGTGACCCAATGGGAACTTTCAATGCCGG
AGATGGCGCTCCAGTTGCCATTCTTAACCGTAATGAACCGGCTTTCTACTGTGTGCCTCCGGCACTTTATGCTCATCTTA
TGGATATTCTTGAGGATGAAGAACTCGGTCGTATTATCGATGAGCGTGCGAATGAACGCGTCATTGAGGTCAACATTGAT
GACTTATAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References