Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-MqsA
Location 948597..949311 Replicon chromosome
Accession NZ_CP050854
Organism Brenneria izadpanahii strain Iran 50

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag HC231_RS04160 Protein ID WP_208229857.1
Coordinates 948597..948992 (+) Length 132 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag HC231_RS04165 Protein ID WP_208229858.1
Coordinates 948982..949311 (+) Length 110 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HC231_RS04145 (HC231_04145) 943828..945375 - 1548 WP_208229854.1 hypothetical protein -
HC231_RS04150 (HC231_04150) 945723..947279 - 1557 WP_208229855.1 methyl-accepting chemotaxis protein -
HC231_RS04155 (HC231_04155) 947801..948493 + 693 WP_208229856.1 glutamine amidotransferase -
HC231_RS04160 (HC231_04160) 948597..948992 + 396 WP_208229857.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
HC231_RS04165 (HC231_04165) 948982..949311 + 330 WP_208229858.1 helix-turn-helix domain-containing protein Antitoxin
HC231_RS04170 (HC231_04170) 949727..950554 + 828 WP_208229859.1 nitrogenase iron protein -
HC231_RS04175 (HC231_04175) 950751..952319 + 1569 WP_208229860.1 nitrogenase iron-iron protein, alpha chain -
HC231_RS04180 (HC231_04180) 952331..952681 + 351 WP_208229861.1 Fe-only nitrogenase subunit delta -
HC231_RS04185 (HC231_04185) 952694..954082 + 1389 WP_208229862.1 Fe-only nitrogenase subunit beta -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-2

(5-126)

Antitoxin

Cro/C1-type helix-turn-helix domain

(53-94)


Sequences

Toxin        


Download         Length: 132 a.a.        Molecular weight: 14802.12 Da        Isoelectric Point: 9.1075

>T153340 WP_208229857.1 NZ_CP050854:948597-948992 [Brenneria izadpanahii]
MDLAIYTTKLFDRKMKKEDVTDVDLCQAAADVMNGDFEADLGGGVLKKRLALQSGKSGGARSIIFFKKGSNVFFFDGWRK
NQITRKGAKEIEEDVLKTYKDFAEVFLQYDAAMITRLKKVKQLREVNCDGC

Download         Length: 396 bp

>T153340 NZ_CP066851:c2539805-2539521 [Salmonella enterica subsp. enterica serovar Heidelberg]
ATGACTTATAAGCTGGCATTTAACGAATCAGCACTAAAAGAGTGGAAAAAAATGGGTCATACCATACAGGAACAGTTTAA
AAAAAAGTTACGGGAACGTCTTGAAAACCCTCGGGTTCCGGCTTCGCAATTACATGGAAGAAAGGATCAGTACAAAATTA
AGCTGCGTGGTGCAGGATACAGACTGGTGTACAGCGTCGAAGATGAAATTATCACGGTAACTGTCATTGGTGTTGGAAAG
CGTGAAAATGATGCCGTCTACAAAATGACACGACACAGAAGCTAA

Antitoxin


Download         Length: 110 a.a.        Molecular weight: 12223.13 Da        Isoelectric Point: 9.6910

>AT153340 WP_208229858.1 NZ_CP050854:948982-949311 [Brenneria izadpanahii]
MAANLKELQALAQELHEHGAMPDETMSRINARVKSRELRERIAKVHIMTGTQIKSMRERYGMSQSTLAYTLGMSVESVSK
WERGEIQPSGPALRILNTIDAKGPEVFVL

Download         Length: 330 bp

>AT153340 NZ_CP066851:c2540043-2539795 [Salmonella enterica subsp. enterica serovar Heidelberg]
ATGGCATTTCAAATTTTAACGACTACTGCAGCAAGCATTACAGAACTGAAACGTGACCCAATGGGAACTTTCAATGCCGG
AGATGGCGCTCCAGTTGCCATTCTTAACCGTAATGAACCGGCTTTCTACTGTGTGCCTCCGGCACTTTATGCTCATCTTA
TGGATATTCTTGAGGATGAAGAACTCGGTCGTATTATCGATGAGCGTGCGAATGAACGCGTCATTGAGGTCAACATTGAT
GACTTATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References