Detailed information of TA system TA153337

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): pmenTA/darT(toxin)
• Location: 927001..928631
• Replicon: chromosome
• Accession: NZ_CP050849
• Organism: Xanthomonas oryzae pv. oryzicola strain GX2019

Toxin (Protein)

• Gene name: pmenT
• Uniprot ID: -
• Locus tag: HED68_RS04240
• Protein ID: WP_263433147.1
• Coordinates: 928071..928631 (-)
• Length: 187 a.a.

Antitoxin (Protein)

• Gene name: pmenA
• Uniprot ID: -
• Locus tag: HED68_RS04235
• Protein ID: WP_149621355.1
• Coordinates: 927001..928074 (-)
• Length: 358 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
HED68_RS04215 (HED68_04185)	922876..923202	-	327	WP_024710580.1	hypothetical protein	-
HED68_RS04220 (HED68_04190)	923506..924786	-	1281	WP_024710581.1	amidohydrolase family protein	-
HED68_RS04225 (HED68_04195)	924783..926192	-	1410	WP_024710582.1	amidohydrolase	-
HED68_RS04230 (HED68_04200)	926332..926892	+	561	WP_044750878.1	DUF924 family protein	-
HED68_RS04235 (HED68_04205)	927001..928074	-	1074	WP_149621355.1	macro domain-containing protein	Antitoxin
HED68_RS04240 (HED68_04210)	928071..928631	-	561	WP_263433147.1	DUF4433 domain-containing protein	Toxin
HED68_RS04245 (HED68_04215)	929055..929981	-	927	WP_024710586.1	Grx4 family monothiol glutaredoxin	-
HED68_RS04250 (HED68_04220)	930027..930818	+	792	WP_024710587.1	polysaccharide deacetylase family protein	-
HED68_RS04260 (HED68_04230)	931122..931793	-	672	WP_024745633.1	class I SAM-dependent methyltransferase	-
HED68_RS04265 (HED68_04235)	932116..932766	-	651	WP_024710589.1	SGNH/GDSL hydrolase family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• ssDNA thymidine ADP-ribosyltransferase, DarT (5-185)

Antitoxin

• Macro domain (18-129)

Sequences

Toxin

Protein

• Length: 187 a.a.
• Molecular weight: 21601.45 Da
• Isoelectric Point: 7.5411

>T153337 WP_263433147.1 NZ_CP050849:c928631-928071 [Xanthomonas oryzae pv. oryzicola]
MHCGNAAVQSSSWVSIGNPELIDKRSSHPVPRPPGGFSNDYVPFYFTPFLPMLRNIHTAWGGIQRRPNEDIVILVSSLHH
VAERRWPFLFTDSHAYCQLASFYSDLSDLDKIDWPLLQARDFRRDPDDPAKFERYQAEALIHRHVPLDGLRGIVCHTDGL
QQTIERQLQERNLKLPVHTRTGWYFR

Nucleotide

• Length: 561 bp

>T153337 NZ_CP066851:840579-840866 [Salmonella enterica subsp. enterica serovar Heidelberg]
ATGCCGATGGAGTTTGAATGGGATGCGAACAAGGCTAAAAGCAACCTGAGGAAGCACGGTGTCCGTTTTGAGGATGCGGT
ACTGGTGTTTGACGATCCCCGACACCTGTCACGTCAGGAGCGTTATGAGAATGGAGAATATCGTTGGCAGACCCTCGGCC
TTGTTCATGGCATTGTGGTCATTCTGGTTGCTCATAGCGTTCGGTTCGAAAGTGGTTTTGAAGTTATCCGTATCATCAGC
GCCCGCAAGGCAGACAGAAAAGAGAGGAATCGTTATGAGCATGGTTAA

Antitoxin

Protein

• Length: 358 a.a.
• Molecular weight: 40084.13 Da
• Isoelectric Point: 6.0089

>AT153337 WP_149621355.1 NZ_CP050849:c928074-927001 [Xanthomonas oryzae pv. oryzicola]
MITFTQGNLLESGAEALVNTVNTVGVMGKGIALMFKERFKENFLRYAAACKDNQVRIGKIFVTEVNELDGPRWIINFPTK
QHWRGDSRIEWITEGLQDLHRFLIENKVKSIAIPPLGAGNGGLDRADVRPLIEEVLAGLDTDILVFEPTLKYQNVAKRSG
VEKLTPARALIAELVRRYWVLGMECGLLEIQKLAWFLERNIERAGLPELDLRFSAHKYGPYADRLRHLLNGLDGSYLHCD
KRISDADPLDVIWFDDNRKSFVQTYLLKSEAKQYIPALEATAALIDGFESPFGMELLATVDWLIVQEGISAQVADVREGI
RHWPGDQEAAARKDRLFDDRALGIALKRLASGAIAVA

Nucleotide

• Length: 1074 bp

>AT153337 NZ_CP066851:840853-841155 [Salmonella enterica subsp. enterica serovar Heidelberg]
ATGAGCATGGTTAAACATAAACGCGGCAACGCATCCGCGCTGAGTGCTCAGCATGAGGCTGAACTGAAGGCGCTGGCGAA
AAAATCAGATGATGAGATTGATTACAGCGACATTCCCGCTTCGGAGGATGGGCAGTGGTCTGAAGCAGTGCGTGGTAAGT
TTTTTCGCCCGTTAAAAACTCAGGCCTCGGTGCGTATTGACGCCGATGTGATGGAGTGGCTGAAACGGCCAGGAAAAGGC
TACCAGACGCGGCTCAATGCCATTCTGCGCGAGGCGATGCTGCGCGAGCAAAATAAGAAATAG