Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | omega-epsilon-zeta/- |
| Location | 639506..641085 | Replicon | chromosome |
| Accession | NZ_CP050849 | ||
| Organism | Xanthomonas oryzae pv. oryzicola strain GX2019 | ||
Toxin (Protein)
| Gene name | avrRxo1 | Uniprot ID | - |
| Locus tag | HED68_RS02905 | Protein ID | WP_149621311.1 |
| Coordinates | 639506..640771 (+) | Length | 422 a.a. |
Antitoxin (Protein)
| Gene name | arc1 | Uniprot ID | A0A0C5UZA4 |
| Locus tag | HED68_RS02910 | Protein ID | WP_044749828.1 |
| Coordinates | 640789..641085 (+) | Length | 99 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| HED68_RS02890 (HED68_02850) | 635499..635864 | - | 366 | WP_224229821.1 | SymE family type I addiction module toxin | - |
| HED68_RS02895 | 637576..638601 | + | 1026 | Protein_547 | hemagglutinin repeat-containing protein | - |
| HED68_RS02900 (HED68_02860) | 638601..639131 | + | 531 | Protein_548 | IS30 family transposase | - |
| HED68_RS02905 (HED68_02865) | 639506..640771 | + | 1266 | WP_149621311.1 | zeta toxin family type III secretion system effector XopAJ/AvrRxo1 | Toxin |
| HED68_RS02910 (HED68_02870) | 640789..641085 | + | 297 | WP_044749828.1 | hypothetical protein | Antitoxin |
| HED68_RS02915 (HED68_02875) | 641307..641573 | + | 267 | Protein_551 | transposase | - |
| HED68_RS02920 (HED68_02880) | 641640..642065 | - | 426 | Protein_552 | integrase core domain-containing protein | - |
| HED68_RS02925 (HED68_02885) | 642194..643235 | + | 1042 | WP_229690555.1 | IS3 family transposase | - |
| HED68_RS02930 (HED68_02890) | 643265..643342 | + | 78 | Protein_554 | anti-sigma factor antagonist | - |
| HED68_RS02935 (HED68_02895) | 643437..643612 | + | 176 | Protein_555 | HAD family hydrolase | - |
| HED68_RS02940 (HED68_02900) | 643828..644580 | - | 753 | WP_024712407.1 | YceI family protein | - |
| HED68_RS02945 (HED68_02905) | 644791..645381 | - | 591 | WP_014504809.1 | malonic semialdehyde reductase | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Genomic island | - | - | 635499..651016 | 15517 | |
| - | inside | IScluster/Tn | - | - | 633596..643235 | 9639 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 422 a.a. Molecular weight: 45201.81 Da Isoelectric Point: 6.9140
>T153336 WP_149621311.1 NZ_CP050849:639506-640771 [Xanthomonas oryzae pv. oryzicola]
MKNKTDIAGIAGLSTSHVSFDDAESKSVLDGSTQSTPEYKFQTPLDQLPARPAGPKSSNTTDAYIHESLPHSVPIAGAST
SAVTHQQATQRKGTDEIYGLGSLPSAGPERWDYLANPGNWHPERRKLHEKLLDQARSSALTLAESLESDGCQPTLFALRG
NTATGKTRIATKKIPVLAAALKKTGGKGCVNPDVFKSSLAKSEAGAKIFSSAQVHSESSFLADRFEGGLRSQKTGSGAIA
SIVVDKRLSRAYEIDSYIQLAKETGRKVELCDIDAPLENSLVGVLQRKPEGEDPRPPYPVVSSGFVAVRSNRMYVIDRFI
ADPSLGNYRLFGTAEDGEKVMVATVIGGEFSVENAELYEKITSPQLSVTGDLADKVIDKELIDRLKNNIADPERAAKTQA
ALEKYSGKSWSAALAAHSELI
MKNKTDIAGIAGLSTSHVSFDDAESKSVLDGSTQSTPEYKFQTPLDQLPARPAGPKSSNTTDAYIHESLPHSVPIAGAST
SAVTHQQATQRKGTDEIYGLGSLPSAGPERWDYLANPGNWHPERRKLHEKLLDQARSSALTLAESLESDGCQPTLFALRG
NTATGKTRIATKKIPVLAAALKKTGGKGCVNPDVFKSSLAKSEAGAKIFSSAQVHSESSFLADRFEGGLRSQKTGSGAIA
SIVVDKRLSRAYEIDSYIQLAKETGRKVELCDIDAPLENSLVGVLQRKPEGEDPRPPYPVVSSGFVAVRSNRMYVIDRFI
ADPSLGNYRLFGTAEDGEKVMVATVIGGEFSVENAELYEKITSPQLSVTGDLADKVIDKELIDRLKNNIADPERAAKTQA
ALEKYSGKSWSAALAAHSELI
Download Length: 1266 bp
>T153336 NZ_CP066851:746176-746460 [Salmonella enterica subsp. enterica serovar Heidelberg]
ATGACTTATGAACTGGAATTCGACCCGAGGGCCTTAAAAGAGTGGCATAAGCTGGGCGATACGGTGAAAGCTCAGCTTAA
GAAAAAGTTGGCTGATGTGCTATTGAACCCCAGAATCGACTCTGCCCGTTTAAACGATCTTCCTGACTGCTATAAAATTA
AGCTTAAATCGTCCGGTTATCGCTTGGTGTACCAGGTTCGGGATGACGTTGTGATTGTGTTTGTTGTCGCGGTCGGTAAG
CGAGAACATTCAGCCGTCTATCACGATGCAAACAAACGGCTTTAG
ATGACTTATGAACTGGAATTCGACCCGAGGGCCTTAAAAGAGTGGCATAAGCTGGGCGATACGGTGAAAGCTCAGCTTAA
GAAAAAGTTGGCTGATGTGCTATTGAACCCCAGAATCGACTCTGCCCGTTTAAACGATCTTCCTGACTGCTATAAAATTA
AGCTTAAATCGTCCGGTTATCGCTTGGTGTACCAGGTTCGGGATGACGTTGTGATTGTGTTTGTTGTCGCGGTCGGTAAG
CGAGAACATTCAGCCGTCTATCACGATGCAAACAAACGGCTTTAG
Antitoxin
Download Length: 99 a.a. Molecular weight: 11327.83 Da Isoelectric Point: 5.2138
>AT153336 WP_044749828.1 NZ_CP050849:640789-641085 [Xanthomonas oryzae pv. oryzicola]
MKTLTGADALEFHKKLKERNKALHASDLELALVHADAVGKERFDLEELEKICDTSDAGRLTDAKERHDIYERMYYVEYPN
VMTLKEFAHIVETLSSWS
MKTLTGADALEFHKKLKERNKALHASDLELALVHADAVGKERFDLEELEKICDTSDAGRLTDAKERHDIYERMYYVEYPN
VMTLKEFAHIVETLSSWS
Download Length: 297 bp
>AT153336 NZ_CP066851:745944-746186 [Salmonella enterica subsp. enterica serovar Heidelberg]
ATGGCCACGCTGAACGTCCGTCTGGATGACAAACTCAAAAATGAGGCTTATGCCGTGCTGGAAAAACTGAACATTACTCC
AACGGAAGCCGTGCGATTACTGTTCCAGTACGTCGCGGAAACGGGGCGCATGCCAGTGAAAACCGTCACTCTTAGCGACA
GTGAAGATGCATTGATTCAGACAGTTCGGGAGAGGCTGTCTAGTCCGCAAAAGGGAATCAAGGTTAGTCTGGATGACTTA
TGA
ATGGCCACGCTGAACGTCCGTCTGGATGACAAACTCAAAAATGAGGCTTATGCCGTGCTGGAAAAACTGAACATTACTCC
AACGGAAGCCGTGCGATTACTGTTCCAGTACGTCGCGGAAACGGGGCGCATGCCAGTGAAAACCGTCACTCTTAGCGACA
GTGAAGATGCATTGATTCAGACAGTTCGGGAGAGGCTGTCTAGTCCGCAAAAGGGAATCAAGGTTAGTCTGGATGACTTA
TGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|