Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | EcnAB/- |
Location | 402638..402999 | Replicon | chromosome |
Accession | NZ_CP050849 | ||
Organism | Xanthomonas oryzae pv. oryzicola strain GX2019 |
Toxin (Protein)
Gene name | EcnB | Uniprot ID | G7TLC7 |
Locus tag | HED68_RS01785 | Protein ID | WP_011257368.1 |
Coordinates | 402865..402999 (+) | Length | 45 a.a. |
Antitoxin (Protein)
Gene name | EcnA | Uniprot ID | G7TLC8 |
Locus tag | HED68_RS01780 | Protein ID | WP_011407410.1 |
Coordinates | 402638..402790 (+) | Length | 51 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
HED68_RS01755 (HED68_01725) | 398982..399665 | - | 684 | WP_014505034.1 | dTMP kinase | - |
HED68_RS01760 (HED68_01730) | 400145..400680 | - | 536 | Protein_333 | GTPase | - |
HED68_RS01765 (HED68_01735) | 400677..401075 | - | 399 | Protein_334 | hypothetical protein | - |
HED68_RS01770 | 401067..401285 | - | 219 | Protein_335 | hypothetical protein | - |
HED68_RS01775 (HED68_01740) | 401607..402530 | + | 924 | WP_014505030.1 | arginase | - |
HED68_RS01780 (HED68_01745) | 402638..402790 | + | 153 | WP_011407410.1 | entericidin A/B family lipoprotein | Antitoxin |
HED68_RS01785 (HED68_01750) | 402865..402999 | + | 135 | WP_011257368.1 | entericidin A/B family lipoprotein | Toxin |
HED68_RS01790 (HED68_01755) | 403242..403451 | + | 210 | WP_011407411.1 | CsbD family protein | - |
HED68_RS01795 (HED68_01760) | 403620..404909 | + | 1290 | WP_024711517.1 | tryptophan--tRNA ligase | - |
HED68_RS01800 (HED68_01765) | 405040..405984 | + | 945 | WP_044749698.1 | MBL fold metallo-hydrolase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 45 a.a. Molecular weight: 4457.33 Da Isoelectric Point: 10.2040
>T153335 WP_011257368.1 NZ_CP050849:402865-402999 [Xanthomonas oryzae pv. oryzicola]
MKRAIVLLVLSMLSVGLLSGCNTVAGAGKDVKGAGEKVEDAARK
MKRAIVLLVLSMLSVGLLSGCNTVAGAGKDVKGAGEKVEDAARK
Download Length: 135 bp
>T153335 NZ_CP066851:364503-364778 [Salmonella enterica subsp. enterica serovar Heidelberg]
ATGGGGCAAAGGGAAATTGAATATTCGGGACAGTTCCAGAAAGATGTAAAACGGGCACAAAAGCGTCATAAGGATGTCGG
CAAACTTAAAACACTTATGACGCTTCTGATTCACCACCCTTTTCCCCTTCCTGCCATTTATAAAGATCACCCGTTACAAG
GTTCATATAGCGGATACCGGGATGCCCATATTGGGCCTGACTGGATTCTTGTTGATAAGATAACGGATGAATGCCTGCGA
TTTGAACGAACAGGAACGCATGCCGATTTATTTTAA
ATGGGGCAAAGGGAAATTGAATATTCGGGACAGTTCCAGAAAGATGTAAAACGGGCACAAAAGCGTCATAAGGATGTCGG
CAAACTTAAAACACTTATGACGCTTCTGATTCACCACCCTTTTCCCCTTCCTGCCATTTATAAAGATCACCCGTTACAAG
GTTCATATAGCGGATACCGGGATGCCCATATTGGGCCTGACTGGATTCTTGTTGATAAGATAACGGATGAATGCCTGCGA
TTTGAACGAACAGGAACGCATGCCGATTTATTTTAA
Antitoxin
Download Length: 51 a.a. Molecular weight: 5046.99 Da Isoelectric Point: 8.7942
>AT153335 WP_011407410.1 NZ_CP050849:402638-402790 [Xanthomonas oryzae pv. oryzicola]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDLQGAGGKVEKTAEKCSDGKC
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDLQGAGGKVEKTAEKCSDGKC
Download Length: 153 bp
>AT153335 NZ_CP066851:364240-364500 [Salmonella enterica subsp. enterica serovar Heidelberg]
ATGGCTGCAAATGCGCTTGTTCGTGCCCGTATCGACGAAACGCTGAAGAATCAGGCGGCAGATGTCCTGGCTGAAATGGG
GTTAACCATTTCTGATTTGATACGGATTACACTGACTAAAGTTGCGCGTGAAAAGGCATTGCCTTTTGATTTGCGGATAC
CCAATGAGTTAACGTCCCGAACGATAGAAAATAGCGAAGCTGGCGTTGACATTCATAAAGCCAAAGATGCTGATGATTTG
TTTGACCAGTTAGGGATCTGA
ATGGCTGCAAATGCGCTTGTTCGTGCCCGTATCGACGAAACGCTGAAGAATCAGGCGGCAGATGTCCTGGCTGAAATGGG
GTTAACCATTTCTGATTTGATACGGATTACACTGACTAAAGTTGCGCGTGAAAAGGCATTGCCTTTTGATTTGCGGATAC
CCAATGAGTTAACGTCCCGAACGATAGAAAATAGCGAAGCTGGCGTTGACATTCATAAAGCCAAAGATGCTGATGATTTG
TTTGACCAGTTAGGGATCTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A0C5UG40 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A0C5V759 |