153335

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) EcnAB/-
Location 402638..402999 Replicon chromosome
Accession NZ_CP050849
Organism Xanthomonas oryzae pv. oryzicola strain GX2019

Toxin (Protein)


Gene name EcnB Uniprot ID G7TLC7
Locus tag HED68_RS01785 Protein ID WP_011257368.1
Coordinates 402865..402999 (+) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID G7TLC8
Locus tag HED68_RS01780 Protein ID WP_011407410.1
Coordinates 402638..402790 (+) Length 51 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HED68_RS01755 (HED68_01725) 398982..399665 - 684 WP_014505034.1 dTMP kinase -
HED68_RS01760 (HED68_01730) 400145..400680 - 536 Protein_333 GTPase -
HED68_RS01765 (HED68_01735) 400677..401075 - 399 Protein_334 hypothetical protein -
HED68_RS01770 401067..401285 - 219 Protein_335 hypothetical protein -
HED68_RS01775 (HED68_01740) 401607..402530 + 924 WP_014505030.1 arginase -
HED68_RS01780 (HED68_01745) 402638..402790 + 153 WP_011407410.1 entericidin A/B family lipoprotein Antitoxin
HED68_RS01785 (HED68_01750) 402865..402999 + 135 WP_011257368.1 entericidin A/B family lipoprotein Toxin
HED68_RS01790 (HED68_01755) 403242..403451 + 210 WP_011407411.1 CsbD family protein -
HED68_RS01795 (HED68_01760) 403620..404909 + 1290 WP_024711517.1 tryptophan--tRNA ligase -
HED68_RS01800 (HED68_01765) 405040..405984 + 945 WP_044749698.1 MBL fold metallo-hydrolase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(23-42)

Antitoxin

(23-42)


Sequences


Toxin        


Download         Length: 45 a.a.        Molecular weight: 4457.33 Da        Isoelectric Point: 10.2040

>T153335 WP_011257368.1 NZ_CP050849:402865-402999 [Xanthomonas oryzae pv. oryzicola]
MKRAIVLLVLSMLSVGLLSGCNTVAGAGKDVKGAGEKVEDAARK

Download         Length: 135 bp

>T153335 NZ_CP066851:364503-364778 [Salmonella enterica subsp. enterica serovar Heidelberg]
ATGGGGCAAAGGGAAATTGAATATTCGGGACAGTTCCAGAAAGATGTAAAACGGGCACAAAAGCGTCATAAGGATGTCGG
CAAACTTAAAACACTTATGACGCTTCTGATTCACCACCCTTTTCCCCTTCCTGCCATTTATAAAGATCACCCGTTACAAG
GTTCATATAGCGGATACCGGGATGCCCATATTGGGCCTGACTGGATTCTTGTTGATAAGATAACGGATGAATGCCTGCGA
TTTGAACGAACAGGAACGCATGCCGATTTATTTTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5046.99 Da        Isoelectric Point: 8.7942

>AT153335 WP_011407410.1 NZ_CP050849:402638-402790 [Xanthomonas oryzae pv. oryzicola]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDLQGAGGKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT153335 NZ_CP066851:364240-364500 [Salmonella enterica subsp. enterica serovar Heidelberg]
ATGGCTGCAAATGCGCTTGTTCGTGCCCGTATCGACGAAACGCTGAAGAATCAGGCGGCAGATGTCCTGGCTGAAATGGG
GTTAACCATTTCTGATTTGATACGGATTACACTGACTAAAGTTGCGCGTGAAAAGGCATTGCCTTTTGATTTGCGGATAC
CCAATGAGTTAACGTCCCGAACGATAGAAAATAGCGAAGCTGGCGTTGACATTCATAAAGCCAAAGATGCTGATGATTTG
TTTGACCAGTTAGGGATCTGA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure
AlphaFold DB A0A0C5UG40


Antitoxin

Source ID Structure
AlphaFold DB A0A0C5V759

References