Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1898817..1898962 Replicon chromosome
Accession NZ_CP050843
Organism Klebsiella pneumoniae strain Bckp186

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1898853..1898955 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1898817..1898962 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HC697_RS09405 1893947..1896007 + 2061 WP_004148850.1 oligopeptidase B -
HC697_RS09410 1896011..1896670 - 660 WP_002911407.1 exodeoxyribonuclease X -
HC697_RS09415 1896749..1896979 - 231 WP_002911406.1 DNA polymerase III subunit theta -
HC697_RS09420 1897092..1897466 + 375 WP_023285314.1 CopC domain-containing protein YobA -
HC697_RS09425 1897470..1898339 + 870 WP_023285313.1 copper homeostasis membrane protein CopD -
HC697_RS09430 1898356..1898694 + 339 WP_002911404.1 YebY family protein -
- 1898817..1898962 - 146 - - Antitoxin
- 1898853..1898955 + 103 - - Toxin
HC697_RS09435 1899330..1899473 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
HC697_RS09440 1899578..1900546 - 969 WP_004151446.1 VirK/YbjX family protein -
HC697_RS09445 1900703..1901356 + 654 WP_023280291.1 protein-serine/threonine phosphatase -
HC697_RS09450 1901353..1901544 - 192 WP_002911395.1 YebW family protein -
HC697_RS09455 1901642..1901881 - 240 WP_002911393.1 YebV family protein -
HC697_RS09460 1901997..1903430 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T153303 NZ_CP050843:1898853-1898955 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT153303 NZ_CP050843:c1898962-1898817 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References