Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3425442..3425587 Replicon chromosome
Accession NZ_CP050834
Organism Klebsiella pneumoniae strain Bckp021

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3425449..3425551 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3425442..3425587 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HC680_RS16935 3420973..3422406 + 1434 WP_032447684.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
HC680_RS16940 3422522..3422761 + 240 WP_002911393.1 YebV family protein -
HC680_RS16945 3422859..3423050 + 192 WP_002911395.1 YebW family protein -
HC680_RS16950 3423047..3423700 - 654 WP_032447686.1 protein-serine/threonine phosphatase -
HC680_RS16955 3423857..3424825 + 969 WP_074185275.1 DUF535 family protein -
HC680_RS16960 3424930..3425073 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 3425442..3425587 + 146 - - Antitoxin
- 3425449..3425551 - 103 - - Toxin
HC680_RS16965 3425710..3426048 - 339 WP_016529031.1 YebY family protein -
HC680_RS16970 3426065..3426934 - 870 WP_004189267.1 copper homeostasis membrane protein CopD -
HC680_RS16975 3426938..3427312 - 375 WP_004151448.1 CopC domain-containing protein YobA -
HC680_RS16980 3427425..3427655 + 231 WP_002911406.1 DNA polymerase III subunit theta -
HC680_RS16985 3427734..3428393 + 660 WP_002911407.1 exodeoxyribonuclease X -
HC680_RS16990 3428397..3430457 - 2061 WP_004151449.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T153264 NZ_CP050834:c3425551-3425449 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT153264 NZ_CP050834:3425442-3425587 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References