Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1921787..1921932 Replicon chromosome
Accession NZ_CP050829
Organism Klebsiella pneumoniae strain Bckp067

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1921823..1921925 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1921787..1921932 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HC709_RS09510 1916917..1918977 + 2061 WP_004151449.1 oligopeptidase B -
HC709_RS09515 1918981..1919640 - 660 WP_002911407.1 exodeoxyribonuclease X -
HC709_RS09520 1919719..1919949 - 231 WP_002911406.1 DNA polymerase III subunit theta -
HC709_RS09525 1920062..1920436 + 375 WP_004151448.1 CopC domain-containing protein YobA -
HC709_RS09530 1920440..1921309 + 870 WP_004175431.1 copper homeostasis membrane protein CopD -
HC709_RS09535 1921326..1921664 + 339 WP_002911404.1 YebY family protein -
- 1921787..1921932 - 146 - - Antitoxin
- 1921823..1921925 + 103 - - Toxin
HC709_RS09540 1922299..1922442 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
HC709_RS09545 1922547..1923515 - 969 WP_004151446.1 VirK/YbjX family protein -
HC709_RS09550 1923672..1924325 + 654 WP_004175436.1 protein-serine/threonine phosphatase -
HC709_RS09555 1924322..1924513 - 192 WP_002911395.1 YebW family protein -
HC709_RS09560 1924611..1924850 - 240 WP_002911393.1 YebV family protein -
HC709_RS09565 1924966..1926399 - 1434 WP_064156927.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T153236 NZ_CP050829:1921823-1921925 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT153236 NZ_CP050829:c1921932-1921787 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACACGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References