Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1826529..1826674 Replicon chromosome
Accession NZ_CP050826
Organism Klebsiella pneumoniae strain Bckp212

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1826565..1826667 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1826529..1826674 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HC649_RS09045 1821659..1823719 + 2061 WP_004151449.1 oligopeptidase B -
HC649_RS09050 1823723..1824382 - 660 WP_002911407.1 exodeoxyribonuclease X -
HC649_RS09055 1824461..1824691 - 231 WP_002911406.1 DNA polymerase III subunit theta -
HC649_RS09060 1824804..1825178 + 375 WP_004151448.1 CopC domain-containing protein YobA -
HC649_RS09065 1825182..1826051 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
HC649_RS09070 1826068..1826406 + 339 WP_016529031.1 YebY family protein -
- 1826529..1826674 - 146 - - Antitoxin
- 1826565..1826667 + 103 - - Toxin
HC649_RS09075 1827042..1827185 - 144 WP_065518782.1 Ecr family regulatory small membrane protein -
HC649_RS09080 1827290..1828258 - 969 WP_004151446.1 VirK/YbjX family protein -
HC649_RS09085 1828415..1829068 + 654 WP_065518783.1 protein-serine/threonine phosphatase -
HC649_RS09090 1829065..1829256 - 192 WP_002911395.1 YebW family protein -
HC649_RS09095 1829354..1829593 - 240 WP_002911393.1 YebV family protein -
HC649_RS09100 1829709..1831142 - 1434 WP_167812973.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T153214 NZ_CP050826:1826565-1826667 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT153214 NZ_CP050826:c1826674-1826529 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References