Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1857641..1857786 Replicon chromosome
Accession NZ_CP050822
Organism Klebsiella pneumoniae strain Bckp091

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1857677..1857779 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1857641..1857786 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HC645_RS09220 1852771..1854831 + 2061 WP_004151449.1 oligopeptidase B -
HC645_RS09225 1854835..1855494 - 660 WP_002911407.1 exodeoxyribonuclease X -
HC645_RS09230 1855573..1855803 - 231 WP_002911406.1 DNA polymerase III subunit theta -
HC645_RS09235 1855916..1856290 + 375 WP_004151448.1 CopC domain-containing protein YobA -
HC645_RS09240 1856294..1857163 + 870 WP_159195797.1 copper homeostasis membrane protein CopD -
HC645_RS09245 1857180..1857518 + 339 WP_167803391.1 YebY family protein -
- 1857641..1857786 - 146 - - Antitoxin
- 1857677..1857779 + 103 - - Toxin
HC645_RS09250 1858154..1858297 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
HC645_RS09255 1858402..1859370 - 969 WP_004151446.1 VirK/YbjX family protein -
HC645_RS09260 1859527..1860180 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
HC645_RS09265 1860177..1860368 - 192 WP_002911395.1 YebW family protein -
HC645_RS09270 1860466..1860705 - 240 WP_002911393.1 YebV family protein -
HC645_RS09275 1860821..1862254 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T153194 NZ_CP050822:1857677-1857779 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT153194 NZ_CP050822:c1857786-1857641 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References