Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-Phd
Location 3601396..3601976 Replicon chromosome
Accession NZ_CP050695
Organism Aquisalimonas sp. 2447

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag HC341_RS16995 Protein ID WP_167783739.1
Coordinates 3601674..3601976 (+) Length 101 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag HC341_RS16990 Protein ID WP_167783738.1
Coordinates 3601396..3601677 (+) Length 94 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HC341_RS16970 3597439..3599175 - 1737 WP_167783734.1 type VI secretion system tip protein VgrG -
HC341_RS16975 3599309..3599875 - 567 WP_167783735.1 DUF2452 domain-containing protein -
HC341_RS16980 3600052..3600951 + 900 WP_167783736.1 SMP-30/gluconolactonase/LRE family protein -
HC341_RS16985 3600964..3601161 + 198 WP_167783737.1 DUF2905 domain-containing protein -
HC341_RS16990 3601396..3601677 + 282 WP_167783738.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
HC341_RS16995 3601674..3601976 + 303 WP_167783739.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
HC341_RS17000 3602571..3603803 + 1233 WP_167783740.1 porin -
HC341_RS17005 3603965..3604588 + 624 WP_167783741.1 porin family protein -
HC341_RS17010 3604664..3605614 + 951 WP_167783742.1 hypothetical protein -
HC341_RS17015 3605833..3606318 + 486 WP_167783743.1 transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-88)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(8-74)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11313.89 Da        Isoelectric Point: 4.7064

>T153130 WP_167783739.1 NZ_CP050695:3601674-3601976 [Aquisalimonas sp. 2447]
VKIVWSPLALERVEDIARYIAEDNPDAAVRWVEELFATVERLADSPKSGRVVPEVGSPRIRELMYGAYRVIYGARDQVDI
LTVRRSSQLLRLSELGDEAT

Download         Length: 303 bp

>T153130 NZ_CP066759:c3175375-3175001 [Escherichia coli O157:H7]
ATGAAAACATTATCCGACACACATGTACGGGAGGTATCTCGCTGCCCGTCTCCCGTCACCATCTGGCAGACACTGCTCAT
CCGACTGCTGGACCAGCATTATGGCCTCACACTGAATGACACACCGTTTGCCGATGAACGTGTGATTGAGCAGCATATTG
AGGCAGGCATTTCACTGTGTGATGCAGTTAATTTTCTCGTGGAAAAATACGCGCTGGTGCGTACCGACCAGCCGGGATTC
AGCACCTGTCCCCGCTCTCAGTTAATAAACAGTATTGATATCCTCCGGGCTCGCCGGGCGACCGGCCTGATGACCCGCGA
CAATTACAGAACGGTAAATAACATTACCCTGGGTAAGTATCCGGAGGCGAAATGA

Antitoxin


Download         Length: 94 a.a.        Molecular weight: 10659.16 Da        Isoelectric Point: 6.2387

>AT153130 WP_167783738.1 NZ_CP050695:3601396-3601677 [Aquisalimonas sp. 2447]
MSRVRVDEDIRPLSEFRAGVATFVKQLHETRRPMVLTQRGRGVAVLVDVHEYEKMQERLEILEEVYKAEEQIASGEGIAH
EDAKAQVLSGLRR

Download         Length: 282 bp

>AT153130 NZ_CP066759:c3175796-3175422 [Escherichia coli O157:H7]
GTGTCAGACAAACTCTCCGGGATAACTCATCCCGATGACAATCACGACCGCCCCTGGTGGGGGCTTCCCTGCACAGTGAG
GCCCTGTTTTGGCGCTCGTCTGGTGCAAGAGGGTAACCGCCTGCATTACCTTGCCGACCGCGCCGGTATCAGAGGCCGCT
TCAGCGACGCAGATGCATACCATCTGGACCAGGCCTTTCCGCTGCTGATGAAACAACTGGAACTCATGCTCACCAGCGGT
GAACTGAATCCCCGATATCAGCATACCGTCACGCTGAATGCAAAAGGGCTGACCTGCGAAGCCGACACCCTCGGCTCCTG
TGGTTACGTTTATCTGGCTGTTTATCCGACACCAGCACCCGCAACCACCTCATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References