153129

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-parE/ParE-RHH
Location 3434480..3435036 Replicon chromosome
Accession NZ_CP050695
Organism Aquisalimonas sp. 2447

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag HC341_RS16170 Protein ID WP_167783593.1
Coordinates 3434746..3435036 (+) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag HC341_RS16165 Protein ID WP_167783592.1
Coordinates 3434480..3434758 (+) Length 93 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HC341_RS16140 3429633..3430856 + 1224 WP_167783589.1 HDOD domain-containing protein -
HC341_RS16145 3431089..3431439 - 351 WP_167783590.1 zinc ribbon domain-containing protein -
HC341_RS16150 3431852..3432391 + 540 WP_174813765.1 DUF1614 domain-containing protein -
HC341_RS16155 3432467..3433336 + 870 WP_167784306.1 SDR family NAD(P)-dependent oxidoreductase -
HC341_RS16160 3433336..3434319 + 984 WP_167783591.1 lipid A deacylase LpxR family protein -
HC341_RS16165 3434480..3434758 + 279 WP_167783592.1 CopG family ribbon-helix-helix protein Antitoxin
HC341_RS16170 3434746..3435036 + 291 WP_167783593.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
HC341_RS16175 3435063..3436421 + 1359 WP_167783594.1 nicotinate phosphoribosyltransferase -
HC341_RS16180 3436565..3437710 + 1146 WP_167783595.1 FAD-dependent oxidoreductase -
HC341_RS16185 3437939..3439165 - 1227 WP_167783596.1 methyltransferase domain-containing protein -
HC341_RS16190 3439193..3439429 - 237 WP_167783597.1 mycothiol system anti-sigma-R factor -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-94)

Antitoxin

Ribbon-helix-helix protein, CopG

(5-42)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 10600.16 Da        Isoelectric Point: 5.1007

>T153129 WP_167783593.1 NZ_CP050695:3434746-3435036 [Aquisalimonas sp. 2447]
VSRVIFTPAAVQDLDRLKGFLQAKGPAAAEKAAQAIIQGMQAIEEMPHIGRPIEDLPPEYRDWLVDFGDSGYIARYRLDG
ETAVVLAIRHQKEVGL

Download         Length: 291 bp

>T153129 NZ_CP066759:2914777-2914884 [Escherichia coli O157:H7]
ATGACGCTCGCGCAGTTTGCCATGATTTTCTGGCACGACCTGGCAGCACCGATCCTGGCGGGAATTATTACCGCAGCGAT
TGTCGGCTGGTGGCGTAACCGGAAGTAA

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10888.16 Da        Isoelectric Point: 4.9973

>AT153129 WP_167783592.1 NZ_CP050695:3434480-3434758 [Aquisalimonas sp. 2447]
MATPTSIKLDEELKDRVQRLANSRERSAHWLMRAAIEEYVDREERREAFKREALEAWETYQATGLHVTSDEMRKWLASWG
TEDELPAPKCHE

Download         Length: 279 bp

>AT153129 NZ_CP066759:c2914724-2914663 [Escherichia coli O157:H7]
TGGTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTTTACCTCTCAACGTGCGGGGGTTTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References