Detailed information of TA system TA153125

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): yoeB-relB/YoeB-YefM
• Location: 2445638..2446140
• Replicon: chromosome
• Accession: NZ_CP050695
• Organism: Aquisalimonas sp. 2447

Toxin (Protein)

• Gene name: yoeB
• Uniprot ID: -
• Locus tag: HC341_RS11460
• Protein ID: WP_167782775.1
• Coordinates: 2445886..2446140 (+)
• Length: 85 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: HC341_RS11455
• Protein ID: WP_167782774.1
• Coordinates: 2445638..2445889 (+)
• Length: 84 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
HC341_RS11440	2443421..2444449	+	1029	WP_167782771.1	AraC family transcriptional regulator	-
HC341_RS11445	2444912..2445175	-	264	WP_167782772.1	Txe/YoeB family addiction module toxin	-
HC341_RS11450	2445172..2445414	-	243	WP_167782773.1	type II toxin-antitoxin system Phd/YefM family antitoxin	-
HC341_RS11455	2445638..2445889	+	252	WP_167782774.1	type II toxin-antitoxin system prevent-host-death family antitoxin	Antitoxin
HC341_RS11460	2445886..2446140	+	255	WP_167782775.1	Txe/YoeB family addiction module toxin	Toxin
HC341_RS11465	2446370..2447179	-	810	WP_167782776.1	ABC transporter permease	-
HC341_RS11470	2447176..2448138	-	963	WP_167782777.1	ATP-binding cassette domain-containing protein	-
HC341_RS11475	2448228..2449430	-	1203	WP_167784227.1	molybdopterin molybdotransferase MoeA	-
HC341_RS11480	2449480..2449911	-	432	WP_167782778.1	hypothetical protein	-
HC341_RS11485	2449921..2450694	-	774	WP_167782779.1	peptidylprolyl isomerase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin YoeB (5-84)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-73)

Sequences

Toxin

Protein

• Length: 85 a.a.
• Molecular weight: 10054.66 Da
• Isoelectric Point: 10.0163

>T153125 WP_167782775.1 NZ_CP050695:2445886-2446140 [Aquisalimonas sp. 2447]
MKLIFSENAWEDYLYWQKTDKKILHRINKLISETKRQPFGGIGKPEPLKHSLAGYWSRRITEEDRMVYKVADGALLIAQL
RYHY

Nucleotide

• Length: 255 bp

>T153125 NZ_CP066759:2153747-2153850 [Escherichia coli O157:H7]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin

Protein

• Length: 84 a.a.
• Molecular weight: 9339.59 Da
• Isoelectric Point: 4.5052

>AT153125 WP_167782774.1 NZ_CP050695:2445638-2445889 [Aquisalimonas sp. 2447]
MDAISYTAARTNLAKTMEQVCEDHSPVIITRSKARSVVMISLEDYEALQETAYLLRAPKNARRLLESVAELEQDGGQEKE
LLE

Nucleotide

• Length: 252 bp

>AT153125 NZ_CP066759:c2153888-2153617 [Escherichia coli O157:H7]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT