Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | parDE/RelE-RHH |
Location | 1513127..1513689 | Replicon | chromosome |
Accession | NZ_CP050695 | ||
Organism | Aquisalimonas sp. 2447 |
Toxin (Protein)
Gene name | parE | Uniprot ID | - |
Locus tag | HC341_RS07135 | Protein ID | WP_167782013.1 |
Coordinates | 1513411..1513689 (+) | Length | 93 a.a. |
Antitoxin (Protein)
Gene name | parD | Uniprot ID | - |
Locus tag | HC341_RS07130 | Protein ID | WP_167782012.1 |
Coordinates | 1513127..1513411 (+) | Length | 95 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
HC341_RS07120 | 1510466..1510810 | - | 345 | WP_167782010.1 | hypothetical protein | - |
HC341_RS07125 | 1510863..1511924 | - | 1062 | WP_167782011.1 | hypothetical protein | - |
HC341_RS07130 | 1513127..1513411 | + | 285 | WP_167782012.1 | ribbon-helix-helix protein, CopG family | Antitoxin |
HC341_RS07135 | 1513411..1513689 | + | 279 | WP_167782013.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
HC341_RS07140 | 1513847..1514233 | + | 387 | WP_167782014.1 | MbcA/ParS/Xre antitoxin family protein | - |
HC341_RS07145 | 1514433..1514738 | - | 306 | WP_167782015.1 | DUF2384 domain-containing protein | - |
HC341_RS07150 | 1515263..1516057 | + | 795 | WP_167782016.1 | metallophosphoesterase | - |
HC341_RS07155 | 1516117..1516869 | + | 753 | WP_167782017.1 | metallophosphoesterase | - |
HC341_RS07160 | 1516880..1517734 | + | 855 | WP_167782018.1 | Fic family protein | - |
HC341_RS07165 | 1517734..1518543 | + | 810 | WP_167782019.1 | metallophosphoesterase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 93 a.a. Molecular weight: 10145.62 Da Isoelectric Point: 4.7440
>T153124 WP_167782013.1 NZ_CP050695:1513411-1513689 [Aquisalimonas sp. 2447]
VRIDWTLPARRSLATITEYIAQDDPVAAVALDDAILGHVAALGDHPRLGRVGRVEGTRELVIASNYLVVYCIDEESGSVW
ILQVLHAKLEWP
VRIDWTLPARRSLATITEYIAQDDPVAAVALDDAILGHVAALGDHPRLGRVGRVEGTRELVIASNYLVVYCIDEESGSVW
ILQVLHAKLEWP
Download Length: 279 bp
>T153124 NZ_CP066759:1036114-1036449 [Escherichia coli O157:H7]
ATGGTAAGCCGATACGTACCCGATATGGGCGATCTGATTTGGGTTGATTTTGACCCGACAAAAGGTAGCGAGCAAGCCGG
ACATCGTCCGGCTGTTGTCCTGAGTCCGTTCATGTACAACAACAAAACAGGTATGTGTCTGTGTGTTCCTTGTACAACGC
AATCAAAAGGATATCCGTTCGAAGTTGTTTTATCCGGTCAGGAACGTGATGGCGTAGCGTTAGCTGATCAGGTAAAAAGT
ATCGCCTGGCGGGCAAGAGGAGCAACGAAGAAAGGAACGGTTGCCCCAGAGGAATTACAACTCATTAAAGCCAAAATTAA
CGTACTGATTGGGTAG
ATGGTAAGCCGATACGTACCCGATATGGGCGATCTGATTTGGGTTGATTTTGACCCGACAAAAGGTAGCGAGCAAGCCGG
ACATCGTCCGGCTGTTGTCCTGAGTCCGTTCATGTACAACAACAAAACAGGTATGTGTCTGTGTGTTCCTTGTACAACGC
AATCAAAAGGATATCCGTTCGAAGTTGTTTTATCCGGTCAGGAACGTGATGGCGTAGCGTTAGCTGATCAGGTAAAAAGT
ATCGCCTGGCGGGCAAGAGGAGCAACGAAGAAAGGAACGGTTGCCCCAGAGGAATTACAACTCATTAAAGCCAAAATTAA
CGTACTGATTGGGTAG
Antitoxin
Download Length: 95 a.a. Molecular weight: 10740.79 Da Isoelectric Point: 4.7352
>AT153124 WP_167782012.1 NZ_CP050695:1513127-1513411 [Aquisalimonas sp. 2447]
MPDTNYTVRIDEALKERFNAAARSEHRSGSQVLRQLMTDYATAMEREVSYDRWFRDQVHEGLDALKRGDTVPQDTVADDA
AERRARLLGGEPSE
MPDTNYTVRIDEALKERFNAAARSEHRSGSQVLRQLMTDYATAMEREVSYDRWFRDQVHEGLDALKRGDTVPQDTVADDA
AERRARLLGGEPSE
Download Length: 285 bp
>AT153124 NZ_CP066759:1035866-1036114 [Escherichia coli O157:H7]
ATGATCCACAGTAGCGTAAAGCGTTGGGGAAATTCACCGGCGGTGCGGATCCCGGCTACGTTAATGCAGGCGCTCAATCT
GAATATTGATGATGAAGTGAAGATTGACCTGGTGGATGGCAAATTAATTATTGAGCCAGTGCGTAAAGAGCCCGTATTTA
CGCTTGCTGAACTGGTCAACGACATCACGCCGGAAAACCTCCACGAGAATATCGACTGGGGAGAGCCGAAAGATAAGGAA
GTCTGGTAA
ATGATCCACAGTAGCGTAAAGCGTTGGGGAAATTCACCGGCGGTGCGGATCCCGGCTACGTTAATGCAGGCGCTCAATCT
GAATATTGATGATGAAGTGAAGATTGACCTGGTGGATGGCAAATTAATTATTGAGCCAGTGCGTAAAGAGCCCGTATTTA
CGCTTGCTGAACTGGTCAACGACATCACGCCGGAAAACCTCCACGAGAATATCGACTGGGGAGAGCCGAAAGATAAGGAA
GTCTGGTAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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