Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/RelE-RHH
Location 1513127..1513689 Replicon chromosome
Accession NZ_CP050695
Organism Aquisalimonas sp. 2447

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag HC341_RS07135 Protein ID WP_167782013.1
Coordinates 1513411..1513689 (+) Length 93 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag HC341_RS07130 Protein ID WP_167782012.1
Coordinates 1513127..1513411 (+) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HC341_RS07120 1510466..1510810 - 345 WP_167782010.1 hypothetical protein -
HC341_RS07125 1510863..1511924 - 1062 WP_167782011.1 hypothetical protein -
HC341_RS07130 1513127..1513411 + 285 WP_167782012.1 ribbon-helix-helix protein, CopG family Antitoxin
HC341_RS07135 1513411..1513689 + 279 WP_167782013.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
HC341_RS07140 1513847..1514233 + 387 WP_167782014.1 MbcA/ParS/Xre antitoxin family protein -
HC341_RS07145 1514433..1514738 - 306 WP_167782015.1 DUF2384 domain-containing protein -
HC341_RS07150 1515263..1516057 + 795 WP_167782016.1 metallophosphoesterase -
HC341_RS07155 1516117..1516869 + 753 WP_167782017.1 metallophosphoesterase -
HC341_RS07160 1516880..1517734 + 855 WP_167782018.1 Fic family protein -
HC341_RS07165 1517734..1518543 + 810 WP_167782019.1 metallophosphoesterase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-88)

Antitoxin

Ribbon-helix-helix protein, CopG

(7-40)


Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 10145.62 Da        Isoelectric Point: 4.7440

>T153124 WP_167782013.1 NZ_CP050695:1513411-1513689 [Aquisalimonas sp. 2447]
VRIDWTLPARRSLATITEYIAQDDPVAAVALDDAILGHVAALGDHPRLGRVGRVEGTRELVIASNYLVVYCIDEESGSVW
ILQVLHAKLEWP

Download         Length: 279 bp

>T153124 NZ_CP066759:1036114-1036449 [Escherichia coli O157:H7]
ATGGTAAGCCGATACGTACCCGATATGGGCGATCTGATTTGGGTTGATTTTGACCCGACAAAAGGTAGCGAGCAAGCCGG
ACATCGTCCGGCTGTTGTCCTGAGTCCGTTCATGTACAACAACAAAACAGGTATGTGTCTGTGTGTTCCTTGTACAACGC
AATCAAAAGGATATCCGTTCGAAGTTGTTTTATCCGGTCAGGAACGTGATGGCGTAGCGTTAGCTGATCAGGTAAAAAGT
ATCGCCTGGCGGGCAAGAGGAGCAACGAAGAAAGGAACGGTTGCCCCAGAGGAATTACAACTCATTAAAGCCAAAATTAA
CGTACTGATTGGGTAG

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 10740.79 Da        Isoelectric Point: 4.7352

>AT153124 WP_167782012.1 NZ_CP050695:1513127-1513411 [Aquisalimonas sp. 2447]
MPDTNYTVRIDEALKERFNAAARSEHRSGSQVLRQLMTDYATAMEREVSYDRWFRDQVHEGLDALKRGDTVPQDTVADDA
AERRARLLGGEPSE

Download         Length: 285 bp

>AT153124 NZ_CP066759:1035866-1036114 [Escherichia coli O157:H7]
ATGATCCACAGTAGCGTAAAGCGTTGGGGAAATTCACCGGCGGTGCGGATCCCGGCTACGTTAATGCAGGCGCTCAATCT
GAATATTGATGATGAAGTGAAGATTGACCTGGTGGATGGCAAATTAATTATTGAGCCAGTGCGTAAAGAGCCCGTATTTA
CGCTTGCTGAACTGGTCAACGACATCACGCCGGAAAACCTCCACGAGAATATCGACTGGGGAGAGCCGAAAGATAAGGAA
GTCTGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References