Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1986618..1986762 Replicon chromosome
Accession NZ_CP050680
Organism Klebsiella variicola strain SHET-01

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1986654..1986756 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1986618..1986762 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HCO75_RS09650 (HCO75_09750) 1981748..1983808 + 2061 WP_012541258.1 oligopeptidase B -
HCO75_RS09655 (HCO75_09755) 1983812..1984471 - 660 WP_012541259.1 exodeoxyribonuclease X -
HCO75_RS09660 (HCO75_09760) 1984550..1984780 - 231 WP_012541260.1 DNA polymerase III subunit theta -
HCO75_RS09665 (HCO75_09765) 1984894..1985268 + 375 WP_012541261.1 CopC domain-containing protein YobA -
HCO75_RS09670 (HCO75_09770) 1985272..1986141 + 870 WP_039103972.1 copper homeostasis membrane protein CopD -
HCO75_RS09675 (HCO75_09775) 1986158..1986496 + 339 WP_008804271.1 YebY family protein -
- 1986618..1986762 - 145 - - Antitoxin
- 1986654..1986756 + 103 - - Toxin
HCO75_RS09680 (HCO75_09780) 1987141..1987284 - 144 WP_048268691.1 Ecr family regulatory small membrane protein -
HCO75_RS09685 (HCO75_09785) 1987388..1988356 - 969 WP_162493241.1 VirK/YbjX family protein -
HCO75_RS09690 (HCO75_09790) 1988513..1989166 + 654 WP_008804273.1 protein-serine/threonine phosphatase -
HCO75_RS09695 (HCO75_09795) 1989163..1989354 - 192 WP_002911395.1 YebW family protein -
HCO75_RS09700 (HCO75_09800) 1989452..1989691 - 240 WP_002911393.1 YebV family protein -
HCO75_RS09705 (HCO75_09805) 1989807..1991240 - 1434 WP_012541265.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T153079 NZ_CP050680:1986654-1986756 [Klebsiella variicola]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 145 bp

>AT153079 NZ_CP050680:c1986762-1986618 [Klebsiella variicola]
ACCGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGT
TGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References